BindingDB PrimarySearch

Found 40 hits Enz. Inhib. hit(s) with Target = 'Acetylcholine receptor protein alpha/beta/delta/gamma chain'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency for Nicotinic acetylcholine receptor alpha-7 (rat brain)				J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50038413 (CHEMBL136284 \| N,N'-(2,3-dihydroxylbenzyl)-N,N,N',...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Binding affinity against nicotinic acetylcholine receptor (nAChR)				J Med Chem 37: 4417-20 (1995) Checked by Author Article DOI: 10.1021/jm00051a021 BindingDB Entry DOI: 10.7270/Q24F1PS9
University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50143282 ((-)-cytisine \| (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...) Show SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplax				J Med Chem 48: 3474-7 (2005) Article DOI: 10.1021/jm050069n BindingDB Entry DOI: 10.7270/Q2N87BJ7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50061562 ((12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	314	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Affinity for Nicotinic acetylcholine receptor alpha4-beta2 in rat brain				J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50166909 (10-Aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien...) Show SMILES C1C2CNCC1c1ccccc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplax				J Med Chem 48: 3474-7 (2005) Article DOI: 10.1021/jm050069n BindingDB Entry DOI: 10.7270/Q2N87BJ7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50166907 (4-nitro-10-azatricyclo[6.3.1.02,7]dodeca-2(7),3,5-...) Show SMILES [O-][N+](=O)c1ccc2C3CC(CNC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplax				J Med Chem 48: 3474-7 (2005) Article DOI: 10.1021/jm050069n BindingDB Entry DOI: 10.7270/Q2N87BJ7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50038415 ((2,3-Dihydroxy-benzyl)-trimethyl-ammonium; bromide...) Show SMILES C[N+](C)(C)Cc1cccc(O)c1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Binding affinity against nicotinic acetylcholine receptor (nAChR)				J Med Chem 37: 4417-20 (1995) Checked by Author Article DOI: 10.1021/jm00051a021 BindingDB Entry DOI: 10.7270/Q24F1PS9
University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50166908 (5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca...) Show SMILES C1C2CNCC1c1cc3nccnc3cc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	3.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplax				J Med Chem 48: 3474-7 (2005) Article DOI: 10.1021/jm050069n BindingDB Entry DOI: 10.7270/Q2N87BJ7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	6.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [125I]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha1 beta gamma delta of electroplax				J Med Chem 48: 3474-7 (2005) Article DOI: 10.1021/jm050069n BindingDB Entry DOI: 10.7270/Q2N87BJ7
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency for Nicotinic acetylcholine receptor alpha4-beta2 (rat brain)				J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50035398 ((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...) Show SMILES CN1CCC[C@H]1c1cc(C)no1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Affinity for Nicotinic acetylcholine receptor alpha4-beta2 in rat brain				J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089157 ((3R,5S,7aR)-3-Heptyl-5-methyl-hexahydro-pyrrolizin...) Show SMILES CCCCCCC[C@@H]1CC[C@H]2CC[C@H](C)N12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089159 ((3R,5S)-3,5-Dibutyl-octahydro-indolizine \| CHEMBL2...) Show SMILES CCCC[C@@H]1CCC2CCC[C@H](CCCC)N12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089158 ((3R,5R)-3,5-Dibutyl-octahydro-indolizine \| CHEMBL2...) Show SMILES CCCC[C@@H]1CCC2CCC[C@@H](CCCC)N12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089162 (7-((3R,5S,7aR)-5-Propyl-hexahydro-pyrrolizin-3-yl)...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089163 ((R)-7-((3R,5S,7aR)-5-Propyl-hexahydro-pyrrolizin-3...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089164 ((S)-7-((3R,5S,7aR)-5-Propyl-hexahydro-pyrrolizin-3...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089160 ((S)-7-((3R,5S,7aR)-5-Methyl-hexahydro-pyrrolizin-3...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50089161 ((R)-7-((3R,5S,7aR)-5-Methyl-hexahydro-pyrrolizin-3...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californica				Bioorg Med Chem Lett 10: 1293-5 (2000) Article DOI: 10.1016/s0960-894x(00)00221-3 BindingDB Entry DOI: 10.7270/Q2JH3KCV
					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023331 ((+)-pyrido[3,4-b]homotropane \| (+/-)-pyrido[3,4-b]...) Show SMILES C1CC2NC1CCc1ccncc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023330 (1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone \| 1...) Show SMILES CC(=O)C1=CCCC2CCC1N2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023331 ((+)-pyrido[3,4-b]homotropane \| (+/-)-pyrido[3,4-b]...) Show SMILES C1CC2NC1CCc1ccncc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023330 (1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone \| 1...) Show SMILES CC(=O)C1=CCCC2CCC1N2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023328 (3-Pyrrolidin-2-yl-pyridine \| CHEMBL1132 \| Nornicot...) Show SMILES C1CNC(C1)c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to torpedo electroplax membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023327 (3-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca-...) Show SMILES Cc1nccc2CCC3CCC(N3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023327 (3-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca-...) Show SMILES Cc1nccc2CCC3CCC(N3)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023328 (3-Pyrrolidin-2-yl-pyridine \| CHEMBL1132 \| Nornicot...) Show SMILES C1CNC(C1)c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023329 (13-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca...) Show SMILES CN1C2CCC1c1cnccc1CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of (-)-[3H]-nicotine binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50023329 (13-Methyl-4,13-diaza-tricyclo[8.2.1.02,7]trideca...) Show SMILES CN1C2CCC1c1cnccc1CC2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stauffer Chemical Company Curated by ChEMBL					Assay Description Inhibition of [3H]-MCC binding to rat brain membranes				J Med Chem 31: 506-9 (1988) Article DOI: 10.1021/jm00398a004 BindingDB Entry DOI: 10.7270/Q2B27T8K
Stauffer Chemical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50125936 (3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibition of currents when compound wascoapplied with acetylcholine to recombinant Torpedo nAcChoR (from 6 oocytes)				J Med Chem 46: 1257-65 (2003) Article DOI: 10.1021/jm020465v BindingDB Entry DOI: 10.7270/Q24J0FVZ
Massachusetts General Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50125935 ((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...) Show SMILES CCOC(=O)c1cncn1[C@H](C)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description In vitro inhibition of 5-[125I]-A-85,380 binding to alpha2 beta4 nicotinic acetylcholine receptor (nAChR) in rat brain				J Med Chem 46: 1257-65 (2003) Article DOI: 10.1021/jm020465v BindingDB Entry DOI: 10.7270/Q24J0FVZ
Massachusetts General Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against Nicotinic Acetylcholine Receptor was determined by measuring the displacement of [3H]-cytisine from a preparation of whole r...				J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50000690 (10,25-dimethoxy-15,15,30-trimethyl-(1S,16R)-7,23-d...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20E+6	n/a	n/a	n/a	n/a
University of California-San Diego Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit the binding of [125I]-alpha-bungarotoxin to nicotinic acetylcholine receptor on membranes prepared from t...				J Med Chem 34: 1798-804 (1991) Article DOI: 10.1021/jm00110a007 BindingDB Entry DOI: 10.7270/Q2TX3DBZ
University of California-San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50038416 ((1,6-trimethyl ammonium)hexane; dibromide \| CHEMBL...) Show SMILES C[N+](C)(C)CCCCCC[N+](C)(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Compound was evaluated for the binding constant for association with nicotinic acetylcholine receptor (nAChR)				J Med Chem 37: 4417-20 (1995) Checked by Author Article DOI: 10.1021/jm00051a021 BindingDB Entry DOI: 10.7270/Q24F1PS9
University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50038414 (CHEMBL138569 \| N,N'-(2,3-dihydroxylbenzyl)-N,N,N',...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Compound was evaluated for the binding constant for association with nicotinic acetylcholine receptor (nAChR)				J Med Chem 37: 4417-20 (1995) Checked by Author Article DOI: 10.1021/jm00051a021 BindingDB Entry DOI: 10.7270/Q24F1PS9
University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50038413 (CHEMBL136284 \| N,N'-(2,3-dihydroxylbenzyl)-N,N,N',...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Compound was evaluated for the binding constant for association with nicotinic acetylcholine receptor (nAChR)				J Med Chem 37: 4417-20 (1995) Checked by Author Article DOI: 10.1021/jm00051a021 BindingDB Entry DOI: 10.7270/Q24F1PS9
University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)				J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine receptor protein alpha/beta/delta/gamma chain (Torpedo californica)	BDBM50035398 ((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...) Show SMILES CN1CCC[C@H]1c1cc(C)no1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.11E+5	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency for Nicotinic acetylcholine receptor alpha4-beta2 (rat brain)				J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair