Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acid-sensing ion channel 1/2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid-sensing ion channel 1/2 (Mus musculus)	BDBM50510034 (CHEMBL4593063) Show SMILES Cc1nn(c(C)c1-c1cccc(F)c1)-c1ccc(CN)cc1 Show InChI InChI=1S/C18H18FN3/c1-12-18(15-4-3-5-16(19)10-15)13(2)22(21-12)17-8-6-14(11-20)7-9-17/h3-10H,11,20H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Promidis Curated by ChEMBL					Assay Description Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence...				ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591
					More data for this Ligand-Target Pair