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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acid-sensing ion channel 1/2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acid-sensing ion channel 1/2


(Mus musculus)
BDBM50510034
PNG
(CHEMBL4593063)
Show SMILES Cc1nn(c(C)c1-c1cccc(F)c1)-c1ccc(CN)cc1
Show InChI InChI=1S/C18H18FN3/c1-12-18(15-4-3-5-16(19)10-15)13(2)22(21-12)17-8-6-14(11-20)7-9-17/h3-10H,11,20H2,1-2H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Promidis

Curated by ChEMBL


Assay Description
Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence...


ACS Med Chem Lett 10: 627-632 (2019)


Article DOI: 10.1021/acsmedchemlett.8b00591
More data for this
Ligand-Target Pair