Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 10'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50262191 ({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-methyloxo...) Show SMILES C[C@H]1O[C@H](C[C@@H]1OP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)n1cnc2c(N)ncnc12 Show InChI InChI=1/C10H16N5O11P3/c1-5-6(24-28(19,20)26-29(21,22)25-27(16,17)18)2-7(23-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7H,2H2,1H3,(H,19,20)(H,21,22)(H2,11,12,13)(H2,16,17,18)/p-3/t5-,6+,7-/s2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Ruhr-University Bochum Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble adenylyl cyclase				J Med Chem 51: 4456-64 (2008) Article DOI: 10.1021/jm800481q BindingDB Entry DOI: 10.7270/Q22N5355
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50158383 (2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,...) Show SMILES C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1/C27H33BrO5S/c1-26-13-11-19(29)15-17(26)3-8-21-22-9-10-24(27(22,2)14-12-23(21)26)25(30)16-33-34(31,32)20-6-4-18(28)5-7-20/h4-7,15,21-24H,3,8-14,16H2,1-2H3/t21-,22-,23-,24+,26-,27-/s2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ruhr-University Bochum Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble adenylyl cyclase				J Med Chem 51: 4456-64 (2008) Article DOI: 10.1021/jm800481q BindingDB Entry DOI: 10.7270/Q22N5355
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50262140 ((17beta)-estra-1,3,5(10)-triene-2,3,17-triol | 2-O...) Show SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)c(O)cc34)[C@@H]1CC[C@@H]2O Show InChI InChI=1/C18H24O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,17,19-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/s2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ruhr-University Bochum Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble adenylyl cyclase				J Med Chem 51: 4456-64 (2008) Article DOI: 10.1021/jm800481q BindingDB Entry DOI: 10.7270/Q22N5355
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50198305 (1,2,3,4,5,6,7,8,13,13,14,14-dodecachloro-1,4,4a,4b...) Show SMILES OC(=O)c1cc2C3C(C4C(c2cc1S(O)(=O)=O)C1(Cl)C(Cl)=C(Cl)C4(Cl)C1(Cl)Cl)C1(Cl)C(Cl)=C(Cl)C3(Cl)C1(Cl)Cl Show InChI InChI=1/C21H8Cl12O5S/c22-11-13(24)18(28)9-7(16(11,26)20(18,30)31)3-1-5(15(34)35)6(39(36,37)38)2-4(3)8-10(9)19(29)14(25)12(23)17(8,27)21(19,32)33/h1-2,7-10H,(H,34,35)(H,36,37,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ruhr-University Bochum Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble adenylyl cyclase				J Med Chem 51: 4456-64 (2008) Article DOI: 10.1021/jm800481q BindingDB Entry DOI: 10.7270/Q22N5355
					More data for this Ligand-Target Pair