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Found 55 hits Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, tissue-nonspecific isozyme' AND taxid = 9913   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068225
PNG
(CHEMBL3403324)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H16N2O4S2/c1-11-2-6-14(7-3-11)22(19,20)16-10-12-4-8-13(9-5-12)21(15,17)18/h2-9,16H,10H2,1H3,(H2,15,17,18)
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50n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068229
PNG
(CHEMBL3403327)
Show SMILES NS(=O)(=O)c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1
Show InChI InChI=1S/C12H11FN2O4S2/c13-9-4-6-11(7-5-9)21(18,19)15-10-2-1-3-12(8-10)20(14,16)17/h1-8,15H,(H2,14,16,17)
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60n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50428400
PNG
(CHEMBL182659 | [(4-Methylphenyl)Sulfonyl]Phenylami...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C13H13NO2S/c1-11-7-9-13(10-8-11)17(15,16)14-12-5-3-2-4-6-12/h2-10,14H,1H3
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70n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068230
PNG
(CHEMBL3403329)
Show SMILES CCOc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C15H17NO3S/c1-3-19-14-8-6-13(7-9-14)16-20(17,18)15-10-4-12(2)5-11-15/h4-11,16H,3H2,1-2H3
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128n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437935
PNG
(CHEMBL2408701)
Show SMILES Brc1ccc2occ(C3Nc4ccccc4S(=O)(=O)N3)c(=O)c2c1
Show InChI InChI=1S/C16H11BrN2O4S/c17-9-5-6-13-10(7-9)15(20)11(8-23-13)16-18-12-3-1-2-4-14(12)24(21,22)19-16/h1-8,16,18-19H
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130n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437931
PNG
(CHEMBL2408705)
Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1
Show InChI InChI=1S/C21H20N4O5S2/c1-3-29-20-17(19(26)16-6-4-5-7-18(16)30-20)12-22-14-8-10-15(11-9-14)32(27,28)25-21-24-23-13(2)31-21/h4-12,20,22H,3H2,1-2H3,(H,24,25)
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250n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068220
PNG
(CHEMBL3403320)
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C14H13FN2O3S/c15-12-5-3-11(4-6-12)14(18)17-9-10-1-7-13(8-2-10)21(16,19)20/h1-8H,9H2,(H,17,18)(H2,16,19,20)
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299n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068228
PNG
(CHEMBL3403317)
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-11(7-9-13)10-16-14(17)12-4-2-1-3-5-12/h1-9H,10H2,(H,16,17)(H2,15,18,19)
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918n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068227
PNG
(CHEMBL3403325)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C13H14N2O4S2/c1-10-5-7-12(8-6-10)21(18,19)15-11-3-2-4-13(9-11)20(14,16)17/h2-9,15H,1H3,(H2,14,16,17)
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950n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50247721
PNG
(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Show SMILES NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C13H13FN2O4S2/c14-11-3-7-13(8-4-11)22(19,20)16-9-10-1-5-12(6-2-10)21(15,17)18/h1-8,16H,9H2,(H2,15,17,18)
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1.25E+3n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM16661
PNG
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C12H11FN2O4S2/c13-9-1-5-12(6-2-9)21(18,19)15-10-3-7-11(8-4-10)20(14,16)17/h1-8,15H,(H2,14,16,17)
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1.39E+3n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50241179
PNG
((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1
Show InChI InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
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1.81E+3n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068218
PNG
(CHEMBL3403318)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-12(7-9-14)10-11-17-15(18)13-4-2-1-3-5-13/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)
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3.96E+3n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068221
PNG
(CHEMBL3403321)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C15H15FN2O3S/c16-13-5-3-12(4-6-13)15(19)18-10-9-11-1-7-14(8-2-11)22(17,20)21/h1-8H,9-10H2,(H,18,19)(H2,17,20,21)
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4.51E+3n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437947
PNG
(CHEMBL1814391)
Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H18N2O5S/c1-2-24-18-15(17(21)14-5-3-4-6-16(14)25-18)11-20-12-7-9-13(10-8-12)26(19,22)23/h3-11,18,20H,2H2,1H3,(H2,19,22,23)
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6.80E+3n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068222
PNG
(CHEMBL3403322)
Show SMILES NS(=O)(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1
Show InChI InChI=1S/C13H11FN2O3S/c14-10-6-4-9(5-7-10)13(17)16-11-2-1-3-12(8-11)20(15,18)19/h1-8H,(H,16,17)(H2,15,18,19)
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1.62E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM16652
PNG
(4-Benzoylamino-benzenesulfonamide | CHEMBL23559 | ...)
Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C13H12N2O3S/c14-19(17,18)12-8-6-11(7-9-12)15-13(16)10-4-2-1-3-5-10/h1-9H,(H,15,16)(H2,14,17,18)
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1.66E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437938
PNG
(CHEMBL1814400)
Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C20H22N2O5S/c1-3-13-8-9-18-16(10-13)19(23)17(20(27-18)26-4-2)12-22-14-6-5-7-15(11-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)
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1.68E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068226
PNG
(CHEMBL1607835)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H18N2O4S2/c1-12-2-6-15(7-3-12)23(20,21)17-11-10-13-4-8-14(9-5-13)22(16,18)19/h2-9,17H,10-11H2,1H3,(H2,16,18,19)
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1.76E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437941
PNG
(CHEMBL1814397)
Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C18H17FN2O5S/c1-2-25-18-15(17(22)14-8-11(19)6-7-16(14)26-18)10-21-12-4-3-5-13(9-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)
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1.80E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437932
PNG
(CHEMBL2408704)
Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1
Show InChI InChI=1S/C21H19FN4O5S2/c1-3-30-20-17(19(27)16-10-13(22)4-9-18(16)31-20)11-23-14-5-7-15(8-6-14)33(28,29)26-21-25-24-12(2)32-21/h4-11,20,23H,3H2,1-2H3,(H,25,26)
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2.10E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437929
PNG
(CHEMBL2408560)
Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1
Show InChI InChI=1S/C23H21N3O5S/c1-2-30-23-19(22(27)18-7-3-4-8-20(18)31-23)15-25-16-10-12-17(13-11-16)32(28,29)26-21-9-5-6-14-24-21/h3-15,23,25H,2H2,1H3,(H,24,26)
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2.20E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437927
PNG
(CHEMBL2408698)
Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1cc(OC)nc(OC)n1
Show InChI InChI=1S/C24H24N4O7S/c1-4-34-23-18(22(29)17-7-5-6-8-19(17)35-23)14-25-15-9-11-16(12-10-15)36(30,31)28-20-13-21(32-2)27-24(26-20)33-3/h5-14,23,25H,4H2,1-3H3,(H,26,27,28)
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2.30E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068219
PNG
(CHEMBL3403319)
Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C13H11FN2O3S/c14-10-3-1-9(2-4-10)13(17)16-11-5-7-12(8-6-11)20(15,18)19/h1-8H,(H,16,17)(H2,15,18,19)
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2.51E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437939
PNG
(CHEMBL1814399)
Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-14(9-22-11-4-3-5-12(8-11)28(21,24)25)16(23)13-6-10(19)7-15(20)17(13)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)
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2.60E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437937
PNG
(CHEMBL2408699)
Show SMILES O=c1c(coc2ccccc12)C1Nc2ccccc2S(=O)(=O)N1
Show InChI InChI=1S/C16H12N2O4S/c19-15-10-5-1-3-7-13(10)22-9-11(15)16-17-12-6-2-4-8-14(12)23(20,21)18-16/h1-9,16-18H
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2.70E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437933
PNG
(CHEMBL2408703)
Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O
Show InChI InChI=1S/C20H22N2O5S/c1-3-13-9-10-17-14(11-13)19(23)15(20(27-17)26-4-2)12-22-16-7-5-6-8-18(16)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)
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2.90E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437934
PNG
(CHEMBL2408702)
Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O
Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-12(9-22-14-5-3-4-6-15(14)28(21,24)25)16(23)11-7-10(19)8-13(20)17(11)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)
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2.90E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437928
PNG
(CHEMBL2408697)
Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccc(OC)nn1
Show InChI InChI=1S/C23H22N4O6S/c1-3-32-23-18(22(28)17-6-4-5-7-19(17)33-23)14-24-15-8-10-16(11-9-15)34(29,30)27-20-12-13-21(31-2)26-25-20/h4-14,23-24H,3H2,1-2H3,(H,25,27)
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3.80E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437942
PNG
(CHEMBL1814396)
Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C18H18N2O5S/c1-2-24-18-15(17(21)14-8-3-4-9-16(14)25-18)11-20-12-6-5-7-13(10-12)26(19,22)23/h3-11,18,20H,2H2,1H3,(H2,19,22,23)
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4.10E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437936
PNG
(CHEMBL2408700)
Show SMILES Fc1ccc2occ(C3Nc4ccccc4S(=O)(=O)N3)c(=O)c2c1
Show InChI InChI=1S/C16H11FN2O4S/c17-9-5-6-13-10(7-9)15(20)11(8-23-13)16-18-12-3-1-2-4-14(12)24(21,22)19-16/h1-8,16,18-19H
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4.30E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437940
PNG
(CHEMBL1814398)
Show SMILES CCOC1Oc2ccc(Br)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C18H17BrN2O5S/c1-2-25-18-15(17(22)14-8-11(19)6-7-16(14)26-18)10-21-12-4-3-5-13(9-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)
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4.40E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437945
PNG
(CHEMBL1814393)
Show SMILES CCOC1Oc2ccc(Br)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H17BrN2O5S/c1-2-25-18-15(17(22)14-9-11(19)3-8-16(14)26-18)10-21-12-4-6-13(7-5-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)
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4.80E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437943
PNG
(CHEMBL1814395)
Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C20H22N2O5S/c1-3-13-5-10-18-16(11-13)19(23)17(20(27-18)26-4-2)12-22-14-6-8-15(9-7-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)
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6.00E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437944
PNG
(CHEMBL1814394)
Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-14(9-22-11-3-5-12(6-4-11)28(21,24)25)16(23)13-7-10(19)8-15(20)17(13)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)
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6.30E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437930
PNG
(CHEMBL2408706)
Show SMILES CCOC1Oc2ccc(Br)cc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1
Show InChI InChI=1S/C23H20BrN3O5S/c1-2-31-23-19(22(28)18-13-15(24)6-11-20(18)32-23)14-26-16-7-9-17(10-8-16)33(29,30)27-21-5-3-4-12-25-21/h3-14,23,26H,2H2,1H3,(H,25,27)
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7.40E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068223
PNG
(CHEMBL3403323)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C13H14N2O4S2/c1-10-2-6-13(7-3-10)21(18,19)15-11-4-8-12(9-5-11)20(14,16)17/h2-9,15H,1H3,(H2,14,16,17)
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9.19E+4n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50437946
PNG
(CHEMBL1814392)
Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H17FN2O5S/c1-2-25-18-15(17(22)14-9-11(19)3-8-16(14)26-18)10-21-12-4-6-13(7-5-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)
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2.20E+5n/an/an/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068225
PNG
(CHEMBL3403324)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H16N2O4S2/c1-11-2-6-14(7-3-11)22(19,20)16-10-12-4-8-13(9-5-12)21(15,17)18/h2-9,16H,10H2,1H3,(H2,15,17,18)
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n/an/a 115n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068229
PNG
(CHEMBL3403327)
Show SMILES NS(=O)(=O)c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1
Show InChI InChI=1S/C12H11FN2O4S2/c13-9-4-6-11(7-5-9)21(18,19)15-10-2-1-3-12(8-10)20(14,16)17/h1-8,15H,(H2,14,16,17)
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n/an/a 150n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50428400
PNG
(CHEMBL182659 | [(4-Methylphenyl)Sulfonyl]Phenylami...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C13H13NO2S/c1-11-7-9-13(10-8-11)17(15,16)14-12-5-3-2-4-6-12/h2-10,14H,1H3
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n/an/a 180n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068230
PNG
(CHEMBL3403329)
Show SMILES CCOc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C15H17NO3S/c1-3-19-14-8-6-13(7-9-14)16-20(17,18)15-10-4-12(2)5-11-15/h4-11,16H,3H2,1-2H3
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n/an/a 310n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068220
PNG
(CHEMBL3403320)
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C14H13FN2O3S/c15-12-5-3-11(4-6-12)14(18)17-9-10-1-7-13(8-2-10)21(16,19)20/h1-8H,9H2,(H,17,18)(H2,16,19,20)
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n/an/a 613n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068227
PNG
(CHEMBL3403325)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C13H14N2O4S2/c1-10-5-7-12(8-6-10)21(18,19)15-11-3-2-4-13(9-11)20(14,16)17/h2-9,15H,1H3,(H2,14,16,17)
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n/an/a 2.24E+3n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068228
PNG
(CHEMBL3403317)
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-11(7-9-13)10-16-14(17)12-4-2-1-3-5-12/h1-9H,10H2,(H,16,17)(H2,15,18,19)
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n/an/a 2.87E+3n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50247721
PNG
(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Show SMILES NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C13H13FN2O4S2/c14-11-3-7-13(8-4-11)22(19,20)16-9-10-1-5-12(6-2-10)21(15,17)18/h1-8,16H,9H2,(H2,15,17,18)
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n/an/a 2.94E+3n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM16661
PNG
(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C12H11FN2O4S2/c13-9-1-5-12(6-2-9)21(18,19)15-10-3-7-11(8-4-10)20(14,16)17/h1-8,15H,(H2,14,16,17)
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n/an/a 3.26E+3n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


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Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068218
PNG
(CHEMBL3403318)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-12(7-9-14)10-11-17-15(18)13-4-2-1-3-5-13/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)
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n/an/a 1.03E+4n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50241179
PNG
((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Show SMILES C1CN2C[C@@H](N=C2S1)c1ccccc1
Show InChI InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
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n/an/a 1.92E+4n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus)
BDBM50068221
PNG
(CHEMBL3403321)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C15H15FN2O3S/c16-13-5-3-12(4-6-13)15(19)18-10-9-11-1-7-14(8-2-11)22(17,20)21/h1-8H,9-10H2,(H,18,19)(H2,17,20,21)
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n/an/a 2.25E+4n/an/an/an/an/an/a



Forman Christian College (A Chartered University)

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...


Citation and Details
More data for this
Ligand-Target Pair
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