Compile Data Set for Download or QSAR

Found 945 hits Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253625 (US9701672, 56) Show SMILES FC(F)(F)CCCOc1ccc(c(Cl)c1)[C@@]1(CC(c2ccc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253635 (US9701672, 66) Show SMILES CCc1cnc(s1)C1=C(c2nnn[nH]2)C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM403547 (US10335401, No. I-57) Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cn1 Show InChI InChI=1S/C26H25F8N3O6S/c1-44(40,41)14-21(38)36-13-19-18(20-8-7-17(12-35-20)43-23(27)28)11-24(26(32,33)34,37-22(19)39)15-3-5-16(6-4-15)42-10-2-9-25(29,30)31/h3-8,12,23H,2,9-11,13-14H2,1H3,(H,36,38)(H,37,39)/t24-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd US Patent					Assay Description A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...				US Patent US10335401 (2019) BindingDB Entry DOI: 10.7270/Q2JM2D0H
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253632 (US9701672, 63) Show SMILES FC(F)(F)CCCCCOc1ccc(c(Cl)c1)[C@@]1(CC(c2ncc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM403538 (US10335401, No. I-47) Show SMILES CC(C)(O)c1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C28H31F6N3O6S/c1-25(2,40)18-7-10-22(35-14-18)20-13-26(28(32,33)34,37-24(39)21(20)15-36-23(38)16-44(3,41)42)17-5-8-19(9-6-17)43-12-4-11-27(29,30)31/h5-10,14,40H,4,11-13,15-16H2,1-3H3,(H,36,38)(H,37,39)/t26-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd US Patent					Assay Description A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...				US Patent US10335401 (2019) BindingDB Entry DOI: 10.7270/Q2JM2D0H
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM247150 ((S,E)-2-Methyl-N-(2,2,2-trifluoro-1-(4-((5,5,5-tri...) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM403534 (US10335401, No. I-43) Show SMILES CC(C)c1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C28H31F6N3O5S/c1-17(2)18-5-10-23(35-14-18)21-13-26(28(32,33)34,37-25(39)22(21)15-36-24(38)16-43(3,40)41)19-6-8-20(9-7-19)42-12-4-11-27(29,30)31/h5-10,14,17H,4,11-13,15-16H2,1-3H3,(H,36,38)(H,37,39)/t26-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd US Patent					Assay Description A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...				US Patent US10335401 (2019) BindingDB Entry DOI: 10.7270/Q2JM2D0H
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201358 (US9187424, 122) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(O)cc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C30H26F6N2O4/c1-18-3-5-19(6-4-18)24-17-28(30(34,35)36,20-7-13-23(14-8-20)42-16-2-15-29(31,32)33)38-27(41)25(24)26(40)37-21-9-11-22(39)12-10-21/h3-14,39H,2,15-17H2,1H3,(H,37,40)(H,38,41)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201322 (US9187424, 86) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(cc2)C(F)(F)F)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C31H25F9N2O3/c1-18-3-5-19(6-4-18)24-17-28(31(38,39)40,20-9-13-23(14-10-20)45-16-2-15-29(32,33)34)42-27(44)25(24)26(43)41-22-11-7-21(8-12-22)30(35,36)37/h3-14H,2,15-17H2,1H3,(H,41,43)(H,42,44)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201319 (US9187424, 83) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C31H25F9N2O4/c1-18-3-5-19(6-4-18)24-17-28(30(35,36)37,20-7-11-22(12-8-20)45-16-2-15-29(32,33)34)42-27(44)25(24)26(43)41-21-9-13-23(14-10-21)46-31(38,39)40/h3-14H,2,15-17H2,1H3,(H,41,43)(H,42,44)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201365 (US9187424, 130) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccno2)C(=O)NC(C1)(c1ccc(OCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C26H21F6N3O4/c1-15-2-4-16(5-3-15)19-14-24(26(30,31)32,17-6-8-18(9-7-17)38-13-11-25(27,28)29)35-23(37)21(19)22(36)34-20-10-12-33-39-20/h2-10,12H,11,13-14H2,1H3,(H,34,36)(H,35,37)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM50090510 (CHEMBL3581716) Show SMILES CC(=O)Nc1cc(cc2CCN(CCc3ccccc3)c12)S(=O)(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C24H23F2N3O3S/c1-16(30)27-23-15-20(33(31,32)28-22-8-7-19(25)14-21(22)26)13-18-10-12-29(24(18)23)11-9-17-5-3-2-4-6-17/h2-8,13-15,28H,9-12H2,1H3,(H,27,30)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description In vitro inhibition of full length human MGAT2 transfected in FreeStyle293 cells assessed as dioleoylglycerol by RapidFire/MS assay				J Med Chem 58: 3892-909 (2015) Article DOI: 10.1021/acs.jmedchem.5b00178 BindingDB Entry DOI: 10.7270/Q2XK8H94
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235245 (US9365558, 68 | US9822074, 68) Show SMILES CS(=O)(=O)NC(=O)C1=C(C[C@](NC1=O)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F)c1ccc(cc1)C1CC1 Show InChI InChI=1S/C29H29F7N2O5S/c1-44(41,42)38-26(40)24-21(19-9-7-18(8-10-19)17-5-6-17)16-27(29(34,35)36,37-25(24)39)22-12-11-20(15-23(22)30)43-14-4-2-3-13-28(31,32)33/h7-12,15,17H,2-6,13-14,16H2,1H3,(H,37,39)(H,38,40)/t27-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235244 (US9365558, 67 | US9822074, 67) Show SMILES CS(=O)(=O)NC(=O)C1=C(C[C@](NC1=O)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F)c1ccc(cc1)C(F)F Show InChI InChI=1S/C27H25F9N2O5S/c1-44(41,42)38-24(40)21-18(15-5-7-16(8-6-15)22(29)30)14-25(27(34,35)36,37-23(21)39)19-10-9-17(13-20(19)28)43-12-4-2-3-11-26(31,32)33/h5-10,13,22H,2-4,11-12,14H2,1H3,(H,37,39)(H,38,40)/t25-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201507 (US9187424, 274) Show SMILES FC(F)Oc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235245 (US9365558, 68 | US9822074, 68) Show SMILES CS(=O)(=O)NC(=O)C1=C(C[C@](NC1=O)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F)c1ccc(cc1)C1CC1 Show InChI InChI=1S/C29H29F7N2O5S/c1-44(41,42)38-26(40)24-21(19-9-7-18(8-10-19)17-5-6-17)16-27(29(34,35)36,37-25(24)39)22-12-11-20(15-23(22)30)43-14-4-2-3-13-28(31,32)33/h7-12,15,17H,2-6,13-14,16H2,1H3,(H,37,39)(H,38,40)/t27-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235244 (US9365558, 67 | US9822074, 67) Show SMILES CS(=O)(=O)NC(=O)C1=C(C[C@](NC1=O)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F)c1ccc(cc1)C(F)F Show InChI InChI=1S/C27H25F9N2O5S/c1-44(41,42)38-24(40)21-18(15-5-7-16(8-6-15)22(29)30)14-25(27(34,35)36,37-23(21)39)19-10-9-17(13-20(19)28)43-12-4-2-3-11-26(31,32)33/h5-10,13,22H,2-4,11-12,14H2,1H3,(H,37,39)(H,38,40)/t25-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM403562 (US10335401, No. I-72) Show SMILES CC(=C)c1ccc(nc1)C1=C(CNC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C28H29F6N3O5S/c1-17(2)18-5-10-23(35-14-18)21-13-26(28(32,33)34,37-25(39)22(21)15-36-24(38)16-43(3,40)41)19-6-8-20(9-7-19)42-12-4-11-27(29,30)31/h5-10,14H,1,4,11-13,15-16H2,2-3H3,(H,36,38)(H,37,39)/t26-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd US Patent					Assay Description A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...				US Patent US10335401 (2019) BindingDB Entry DOI: 10.7270/Q2JM2D0H
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201537 (US9187424, 304 | US9187424, 309) Show SMILES Fc1cc(ccc1OCCCCCC(F)(F)F)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc2ccccc2c1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM247150 ((S,E)-2-Methyl-N-(2,2,2-trifluoro-1-(4-((5,5,5-tri...) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253633 (US9701672, 64) Show SMILES FC(F)(F)CCCOc1ccc(c(Cl)c1)[C@@]1(CC(c2ncc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM403549 (US10335401, No. I-59) Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F Show InChI InChI=1S/C26H25F8N3O5S/c1-43(40,41)14-21(38)36-13-19-18(20-8-3-15(12-35-20)22(27)28)11-24(26(32,33)34,37-23(19)39)16-4-6-17(7-5-16)42-10-2-9-25(29,30)31/h3-8,12,22H,2,9-11,13-14H2,1H3,(H,36,38)(H,37,39)/t24-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd US Patent					Assay Description A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...				US Patent US10335401 (2019) BindingDB Entry DOI: 10.7270/Q2JM2D0H
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM50090666 (CHEMBL3581717) Show SMILES CC(=O)Nc1cc(cc2CCN(CCc3ccc(F)cc3)c12)S(=O)(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C24H22F3N3O3S/c1-15(31)28-23-14-20(34(32,33)29-22-7-6-19(26)13-21(22)27)12-17-9-11-30(24(17)23)10-8-16-2-4-18(25)5-3-16/h2-7,12-14,29H,8-11H2,1H3,(H,28,31)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description In vitro inhibition of full length human MGAT2 transfected in FreeStyle293 cells assessed as dioleoylglycerol by RapidFire/MS assay				J Med Chem 58: 3892-909 (2015) Article DOI: 10.1021/acs.jmedchem.5b00178 BindingDB Entry DOI: 10.7270/Q2XK8H94
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM247168 (1-(5-Cyclopropylthiazol-2-yl)ethanone | US9701672,...) Show SMILES FC(F)(F)CCCCc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CC3)n2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253628 (US9701672, 59) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ncc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253626 (US9701672, 57) Show SMILES COc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253649 ((S)—N-(4-(5-Ethylthiophen-2-yl)-2-oxo-6-(4-((...) Show SMILES CCc1ccc(s1)C1=C(NC(=O)CS(C)(=O)=O)C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C27H30F6N2O5S2/c1-3-19-11-12-21(41-19)20-15-25(27(31,32)33,35-24(37)23(20)34-22(36)16-42(2,38)39)17-7-9-18(10-8-17)40-14-6-4-5-13-26(28,29)30/h7-12H,3-6,13-16H2,1-2H3,(H,34,36)(H,35,37)/t25-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM247154 (1-(5-Methylthiazol-2-yl)ethanone | US9701672, 8) Show SMILES FC(F)(F)CCCCCOc1ccc(cc1)[C@@]1(CC(c2ccc(s2)C2CC2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM50433276 (CHEMBL2376316) Show SMILES CCC1(CC)CNc2ccc(cc2C(=O)N1)S(=O)(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C19H21F2N3O3S/c1-3-19(4-2)11-22-16-8-6-13(10-14(16)18(25)23-19)28(26,27)24-17-7-5-12(20)9-15(17)21/h5-10,22,24H,3-4,11H2,1-2H3,(H,23,25)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...				Bioorg Med Chem Lett 23: 2721-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.084 BindingDB Entry DOI: 10.7270/Q2GB25DM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM272063 (US10065945, Example 57) Show SMILES C[C@@H](N1CCc2ccc(cc2C1)S(=O)(=O)Nc1nc(no1)C(=O)N1CCCC1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C24H25F2N5O4S/c1-15(17-10-19(25)13-20(26)11-17)31-9-6-16-4-5-21(12-18(16)14-31)36(33,34)29-24-27-22(28-35-24)23(32)30-7-2-3-8-30/h4-5,10-13,15H,2-3,6-9,14H2,1H3,(H,27,28,29)/t15-/m1/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	25
Merck Sharp & Dohme Corp US Patent					Assay Description A solution of 1 M LiHMDS in THF (51.7 ml, 51.7 mmol) was added dropwise to a mixture of Intermediate 3 (7.5 g, 17.2 mmol) and 5-(tert-butyl)-4-methyl...				US Patent US10065945 (2018) BindingDB Entry DOI: 10.7270/Q24X59TJ
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM403570 (US10335401, No. I-86) Show SMILES CS(=O)(=O)CC(=O)NCC1=C(C[C@](NC1=O)(c1ccc(CCC(F)(F)F)cc1)C(F)(F)F)c1ccc(cn1)C(F)F Show InChI InChI=1S/C25H23F8N3O4S/c1-41(39,40)13-20(37)35-12-18-17(19-7-4-15(11-34-19)21(26)27)10-23(25(31,32)33,36-22(18)38)16-5-2-14(3-6-16)8-9-24(28,29)30/h2-7,11,21H,8-10,12-13H2,1H3,(H,35,37)(H,36,38)/t23-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd US Patent					Assay Description A full-length human MGAT2 gene to which a Flag-tag had been added at the N-terminal was inserted into pFastBac (from Invitrogen). A recombinant bacul...				US Patent US10335401 (2019) BindingDB Entry DOI: 10.7270/Q2JM2D0H
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM38199 (US10093650, Example 7 | US10329273, Example 22) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(n2)C2CC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F Show InChI InChI=1S/C12H17O3P/c1-11(2)9-12(3,13)16(14,15-11)10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US10329273 (2019) BindingDB Entry DOI: 10.7270/Q2MP55KP
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201531 (US9187424, 298) Show SMILES CCCCCCC#CC1(CC(=C(NC(=O)CNS(C)(=O)=O)C(=O)N1)c1ccc(C)cc1)C(F)(F)F Show InChI InChI=1S/C24H30F3N3O4S/c1-4-5-6-7-8-9-14-23(24(25,26)27)15-19(18-12-10-17(2)11-13-18)21(22(32)30-23)29-20(31)16-28-35(3,33)34/h10-13,28H,4-8,15-16H2,1-3H3,(H,29,31)(H,30,32)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235259 (US9365558, 82 | US9822074, 82) Show SMILES CCc1ccc(cc1)C1=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N[C@@](C)(C1)c1ccc(OCCCC(F)(F)F)cc1 Show InChI InChI=1S/C28H31F3N2O5S/c1-3-18-5-7-19(8-6-18)23-17-27(2,20-9-11-21(12-10-20)38-16-4-15-28(29,30)31)32-25(34)24(23)26(35)33-39(36,37)22-13-14-22/h5-12,22H,3-4,13-17H2,1-2H3,(H,32,34)(H,33,35)/t27-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201529 (US9187424, 296) Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2F)cc1 Show InChI InChI=1S/C31H27F7N2O4/c1-18-4-13-23(25(32)16-18)24-17-29(31(36,37)38,19-5-9-22(10-6-19)44-15-3-14-30(33,34)35)40-28(42)26(24)27(41)39-20-7-11-21(43-2)12-8-20/h4-13,16H,3,14-15,17H2,1-2H3,(H,39,41)(H,40,42)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201513 (US9187424, 280) Show SMILES FC(F)Oc1ccc(cc1)C1=C(C(=O)Nc2cccnc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C29H23F8N3O4/c30-26(31)44-21-8-4-17(5-9-21)22-15-27(29(35,36)37,18-6-10-20(11-7-18)43-14-2-12-28(32,33)34)40-25(42)23(22)24(41)39-19-3-1-13-38-16-19/h1,3-11,13,16,26H,2,12,14-15H2,(H,39,41)(H,40,42)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201512 (US9187424, 279) Show SMILES Cc1ccc(cc1)C1=C(NC(=O)CS(C)(=O)=O)C(=O)NC(C1)(c1ccc(OCc2ccccc2)cc1)C(F)(F)F Show InChI InChI=1S/C29H27F3N2O5S/c1-19-8-10-21(11-9-19)24-16-28(29(30,31)32,34-27(36)26(24)33-25(35)18-40(2,37)38)22-12-14-23(15-13-22)39-17-20-6-4-3-5-7-20/h3-15H,16-18H2,1-2H3,(H,33,35)(H,34,36)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201511 (US9187424, 278) Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCCC(F)(F)F)cc1F)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201510 (US9187424, 277) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(CC2CC2)cc1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201317 (US9187424, 81 | US9187424, 91) Show SMILES COc1ccc(C2=C(C#N)C(=O)NC(C2)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C24H19F7N2O3/c1-35-16-7-8-17(20(25)11-16)18-12-22(24(29,30)31,33-21(34)19(18)13-32)14-3-5-15(6-4-14)36-10-2-9-23(26,27)28/h3-8,11H,2,9-10,12H2,1H3,(H,33,34)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201320 (US9187424, 84) Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1F Show InChI InChI=1S/C31H27F7N2O4/c1-18-4-6-19(7-5-18)23-17-29(31(36,37)38,20-8-11-22(12-9-20)44-15-3-14-30(33,34)35)40-28(42)26(23)27(41)39-21-10-13-25(43-2)24(32)16-21/h4-13,16H,3,14-15,17H2,1-2H3,(H,39,41)(H,40,42)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201318 (US9187424, 82) Show SMILES Cc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C31H28F6N2O3/c1-19-4-8-21(9-5-19)25-18-29(31(35,36)37,22-10-14-24(15-11-22)42-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-23-12-6-20(2)7-13-23/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201239 (US9187424, 6-2) Show SMILES COc1ccc(NC(=O)C2=C(C[C@](NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C31H28F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)/t29-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201444 (US9187424, 210) Show SMILES FC(F)(F)CCCOc1ccc(cc1)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc2CCCCc2c1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201401 (US9187424, 167) Show SMILES FC(F)Oc1ccc(cc1)C1=C(NC(=O)c2ccno2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C27H21F8N3O5/c28-24(29)42-18-6-2-15(3-7-18)19-14-25(27(33,34)35,38-23(40)21(19)37-22(39)20-10-12-36-43-20)16-4-8-17(9-5-16)41-13-1-11-26(30,31)32/h2-10,12,24H,1,11,13-14H2,(H,37,39)(H,38,40)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201509 (US9187424, 276) Show SMILES Fc1cc(OCCCCCC(F)(F)F)ccc1C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc2ccccc2c1)C(F)(F)F Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201508 (US9187424, 275) Show SMILES FC(F)Oc1ccc(cc1)C1=C(NC(=O)c2ccncc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F Show InChI InChI=1S/C29H23F8N3O4/c30-26(31)44-21-6-2-17(3-7-21)22-16-27(29(35,36)37,19-4-8-20(9-5-19)43-15-1-12-28(32,33)34)40-25(42)23(22)39-24(41)18-10-13-38-14-11-18/h2-11,13-14,26H,1,12,15-16H2,(H,39,41)(H,40,42)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235217 (US9365558, 40 | US9822074, 40) Show SMILES CCCCCCCc1cnc(s1)[C@@]1(CC(=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)c1ccc(C)cc1)C(F)(F)F Show InChI InChI=1S/C27H32F3N3O4S2/c1-3-4-5-6-7-8-19-16-31-25(38-19)26(27(28,29)30)15-21(18-11-9-17(2)10-12-18)22(23(34)32-26)24(35)33-39(36,37)20-13-14-20/h9-12,16,20H,3-8,13-15H2,1-2H3,(H,32,34)(H,33,35)/t26-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235247 (US9365558, 70 | US9822074, 70) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ncc(s2)C2CC2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F Show InChI InChI=1S/C26H24F7N3O5S2/c27-18-10-14(41-9-1-8-25(28,29)30)4-7-17(18)24(26(31,32)33)11-16(23-34-12-19(42-23)13-2-3-13)20(21(37)35-24)22(38)36-43(39,40)15-5-6-15/h4,7,10,12-13,15H,1-3,5-6,8-9,11H2,(H,35,37)(H,36,38)/t24-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235250 (US9365558, 73 | US9822074, 73) Show SMILES FC(F)(F)CCCCc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F Show InChI InChI=1S/C28H30F6N4O4S/c29-27(30,31)13-2-1-3-17-6-8-19(9-7-17)26(28(32,33)34)15-21(22-12-14-38(36-22)16-18-4-5-18)23(24(39)35-26)25(40)37-43(41,42)20-10-11-20/h6-9,12,14,18,20H,1-5,10-11,13,15-16H2,(H,35,39)(H,37,40)/t26-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair

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