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Compile Data Set for Download or QSAR

Found 18 hits Enz. Inhib. hit(s) with Target = 'Alpha-glucosidase' AND taxid = 9913   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-glucosidase


(Bos taurus)
BDBM18351
PNG
((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
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n/an/a 400n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver


J Med Chem 37: 3701-6 (1994)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283602
PNG
(6a-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro...)
Show SMILES OCC12OC(Nc3ccccc3)=NC1C(O)C(O)C2O
Show InChI InChI=1S/C13H16N2O5/c16-6-13-10(8(17)9(18)11(13)19)15-12(20-13)14-7-4-2-1-3-5-7/h1-5,8-11,16-19H,6H2,(H,14,15)
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n/an/a 571n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283603
PNG
(4-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro-...)
Show SMILES OCC1C(O)C(O)C2OC(Nc3ccccc3)=NC12
Show InChI InChI=1S/C13H16N2O4/c16-6-8-9-12(11(18)10(8)17)19-13(15-9)14-7-4-2-1-3-5-7/h1-5,8-12,16-18H,6H2,(H,14,15)
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n/an/a 3.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM18351
PNG
((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
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n/an/a 2.10E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver


J Med Chem 37: 3701-6 (1994)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283599
PNG
(5,7a-Bis-hydroxymethyl-3-phenylamino-2,4a,5,6,7,7a...)
Show SMILES OCC1(O)C(O)C(O)C2(CO)OCC(Nc3ccccc3)=NC12
Show InChI InChI=1S/C15H20N2O6/c18-7-14(22)11(20)12(21)15(8-19)13(14)17-10(6-23-15)16-9-4-2-1-3-5-9/h1-5,11-13,18-22H,6-8H2,(H,16,17)
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n/an/a 2.39E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 4.69E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283602
PNG
(6a-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro...)
Show SMILES OCC12OC(Nc3ccccc3)=NC1C(O)C(O)C2O
Show InChI InChI=1S/C13H16N2O5/c16-6-13-10(8(17)9(18)11(13)19)15-12(20-13)14-7-4-2-1-3-5-7/h1-5,8-11,16-19H,6H2,(H,14,15)
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n/an/a 5.17E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50407255
PNG
(CHEMBL2114189)
Show SMILES CC[C@H]1NC[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO2/c1-2-4-6(9)5(8)3-7-4/h4-9H,2-3H2,1H3/t4-,5-,6-/m1/s1
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n/an/a 8.90E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver


J Med Chem 37: 3701-6 (1994)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283604
PNG
(6-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro-...)
Show SMILES OCC1(O)C(O)C(O)C2N=C(Nc3ccccc3)OC12
Show InChI InChI=1S/C13H16N2O5/c16-6-13(19)10(18)9(17)8-11(13)20-12(15-8)14-7-4-2-1-3-5-7/h1-5,8-11,16-19H,6H2,(H,14,15)
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n/an/a 1.53E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50037814
PNG
(2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol | CHEMB...)
Show SMILES OCC1NC(CO)C(O)C1O
Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2
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n/an/a 1.70E+5n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver


J Med Chem 37: 3701-6 (1994)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283600
PNG
(5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120)
Show SMILES NC1C(O)C(O)C(O)C1O
Show InChI InChI=1S/C5H11NO4/c6-1-2(7)4(9)5(10)3(1)8/h1-5,7-10H,6H2
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n/an/a 2.41E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283601
PNG
(2-Phenylamino-4,5,6,6a-tetrahydro-3aH-cyclopentaox...)
Show SMILES OC1C(O)C2OC(Nc3ccccc3)=NC2C1O
Show InChI InChI=1S/C12H14N2O4/c15-8-7-11(10(17)9(8)16)18-12(14-7)13-6-4-2-1-3-5-6/h1-5,7-11,15-17H,(H,13,14)
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283598
PNG
(5-Amino-1-hydroxymethyl-cyclopentane-1,2,3,4-tetra...)
Show SMILES NC1C(O)C(O)C(O)C1(O)CO
Show InChI InChI=1S/C6H13NO5/c7-4-2(9)3(10)5(11)6(4,12)1-8/h2-5,8-12H,1,7H2
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283601
PNG
(2-Phenylamino-4,5,6,6a-tetrahydro-3aH-cyclopentaox...)
Show SMILES OC1C(O)C2OC(Nc3ccccc3)=NC2C1O
Show InChI InChI=1S/C12H14N2O4/c15-8-7-11(10(17)9(8)16)18-12(14-7)13-6-4-2-1-3-5-6/h1-5,7-11,15-17H,(H,13,14)
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM18351
PNG
((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50283598
PNG
(5-Amino-1-hydroxymethyl-cyclopentane-1,2,3,4-tetra...)
Show SMILES NC1C(O)C(O)C(O)C1(O)CO
Show InChI InChI=1S/C6H13NO5/c7-4-2(9)3(10)5(11)6(4,12)1-8/h2-5,8-12H,1,7H2
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n/an/a 3.63E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity was determined against bovine liver beta galactosidase


Citation and Details
More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50240725
PNG
((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol | C...)
Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5-,6-/m1/s1
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n/an/a 5.20E+5n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver


J Med Chem 37: 3701-6 (1994)

More data for this
Ligand-Target Pair
Alpha-glucosidase


(Bos taurus)
BDBM50403869
PNG
(CHEMBL2115197)
Show SMILES CC[C@H]1NC[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO2/c1-2-4-6(9)5(8)3-7-4/h4-9H,2-3H2,1H3/t4-,5+,6-/m1/s1
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n/an/a 5.40E+5n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver


J Med Chem 37: 3701-6 (1994)

More data for this
Ligand-Target Pair