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Compile Data Set for Download or QSAR

Found 337 hits Enz. Inhib. hit(s) with Target = 'Angiotensin II type 1a (AT-1a) receptor' AND taxid = 9913   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029907
PNG
(4'-(1-Benzyl-4-butyl-6-oxo-1,6-dihydro-pyrimidin-5...)
Show SMILES CCCCc1ncn(Cc2ccccc2)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C29H28N2O3/c1-2-3-13-27-26(28(32)31(20-30-27)19-22-9-5-4-6-10-22)18-21-14-16-23(17-15-21)24-11-7-8-12-25(24)29(33)34/h4-12,14-17,20H,2-3,13,18-19H2,1H3,(H,33,34)
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>4n/an/an/an/an/an/an/an/a



Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029909
PNG
(4'-[4-Butyl-1-(2-carboxy-benzyl)-6-oxo-1,6-dihydro...)
Show SMILES CCCCc1ncn(Cc2ccccc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C30H28N2O5/c1-2-3-12-27-26(28(33)32(19-31-27)18-22-8-4-5-10-24(22)29(34)35)17-20-13-15-21(16-14-20)23-9-6-7-11-25(23)30(36)37/h4-11,13-16,19H,2-3,12,17-18H2,1H3,(H,34,35)(H,36,37)
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>4n/an/an/an/an/an/an/an/a



Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029911
PNG
(2-{4-Butyl-2-methyl-6-oxo-5-[2'-(1H-tetrazol-5-yl)...)
Show SMILES CCCCc1nc(C)n(Cc2ccccc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C31H30N6O3/c1-3-4-13-28-27(30(38)37(20(2)32-28)19-23-9-5-6-11-25(23)31(39)40)18-21-14-16-22(17-15-21)24-10-7-8-12-26(24)29-33-35-36-34-29/h5-12,14-17H,3-4,13,18-19H2,1-2H3,(H,39,40)(H,33,34,35,36)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029903
PNG
(3-Benzyl-6-butyl-2-methyl-5-[2'-(1H-tetrazol-5-yl)...)
Show SMILES CCCCc1nc(C)n(Cc2ccccc2)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C30H30N6O/c1-3-4-14-28-27(30(37)36(21(2)31-28)20-23-10-6-5-7-11-23)19-22-15-17-24(18-16-22)25-12-8-9-13-26(25)29-32-34-35-33-29/h5-13,15-18H,3-4,14,19-20H2,1-2H3,(H,32,33,34,35)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029896
PNG
(4'-(2-Butyl-6-oxo-6H-pyrimidin-1-ylmethyl)-bipheny...)
Show SMILES CCCCc1nccc(=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C22H22N2O3/c1-2-3-8-20-23-14-13-21(25)24(20)15-16-9-11-17(12-10-16)18-6-4-5-7-19(18)22(26)27/h4-7,9-14H,2-3,8,15H2,1H3,(H,26,27)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50241491
PNG
(2-{4-Butyl-2-methyl-6-oxo-5-[2'-(1H-tetrazol-5-yl)...)
Show SMILES CCCCc1nc(C)n(Cc2sccc2C(=O)OC)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C30H30N6O3S/c1-4-5-10-26-25(29(37)36(19(2)31-26)18-27-24(15-16-40-27)30(38)39-3)17-20-11-13-21(14-12-20)22-8-6-7-9-23(22)28-32-34-35-33-28/h6-9,11-16H,4-5,10,17-18H2,1-3H3,(H,32,33,34,35)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50241501
PNG
(6-Butyl-2-methyl-5-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES CCCCc1nc(C)n(Cc2cccs2)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C28H28N6OS/c1-3-4-11-26-25(28(35)34(19(2)29-26)18-22-8-7-16-36-22)17-20-12-14-21(15-13-20)23-9-5-6-10-24(23)27-30-32-33-31-27/h5-10,12-16H,3-4,11,17-18H2,1-2H3,(H,30,31,32,33)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029892
PNG
(2-{4-Butyl-2-methyl-6-oxo-5-[2'-(1H-tetrazol-5-yl)...)
Show SMILES CCCCc1nc(C)n(Cc2sccc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C29H28N6O3S/c1-3-4-9-25-24(28(36)35(18(2)30-25)17-26-23(29(37)38)14-15-39-26)16-19-10-12-20(13-11-19)21-7-5-6-8-22(21)27-31-33-34-32-27/h5-8,10-15H,3-4,9,16-17H2,1-2H3,(H,37,38)(H,31,32,33,34)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029901
PNG
(2-{4-Butyl-2-methyl-6-oxo-5-[2'-(1H-tetrazol-5-yl)...)
Show SMILES CCCCc1nc(C)n(Cc2occc2C(=O)OC)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C30H30N6O4/c1-4-5-10-26-25(29(37)36(19(2)31-26)18-27-24(15-16-40-27)30(38)39-3)17-20-11-13-21(14-12-20)22-8-6-7-9-23(22)28-32-34-35-33-28/h6-9,11-16H,4-5,10,17-18H2,1-3H3,(H,32,33,34,35)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029897
PNG
(4'-[4-Butyl-1-(4-carboxy-benzyl)-6-oxo-1,6-dihydro...)
Show SMILES CCCCc1ncn(Cc2ccc(cc2)C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C30H28N2O5/c1-2-3-8-27-26(28(33)32(19-31-27)18-21-11-15-23(16-12-21)29(34)35)17-20-9-13-22(14-10-20)24-6-4-5-7-25(24)30(36)37/h4-7,9-16,19H,2-3,8,17-18H2,1H3,(H,34,35)(H,36,37)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029902
PNG
(6-Butyl-2-methyl-5-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H24N6O/c1-3-4-9-21-20(23(30)25-15(2)24-21)14-16-10-12-17(13-11-16)18-7-5-6-8-19(18)22-26-28-29-27-22/h5-8,10-13H,3-4,9,14H2,1-2H3,(H,24,25,30)(H,26,27,28,29)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029904
PNG
(4'-[4-Butyl-1-(2-carboxy-benzyl)-2-methyl-6-oxo-1,...)
Show SMILES CCCCc1nc(C)n(Cc2ccccc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C31H30N2O5/c1-3-4-13-28-27(18-21-14-16-22(17-15-21)24-10-7-8-12-26(24)31(37)38)29(34)33(20(2)32-28)19-23-9-5-6-11-25(23)30(35)36/h5-12,14-17H,3-4,13,18-19H2,1-2H3,(H,35,36)(H,37,38)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029894
PNG
(4'-(4-Butyl-2-methyl-6-oxo-1,6-dihydro-pyrimidin-5...)
Show SMILES CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C23H24N2O3/c1-3-4-9-21-20(22(26)25-15(2)24-21)14-16-10-12-17(13-11-16)18-7-5-6-8-19(18)23(27)28/h5-8,10-13H,3-4,9,14H2,1-2H3,(H,27,28)(H,24,25,26)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029895
PNG
(2-{4-Butyl-2-methyl-6-oxo-5-[2'-(1H-tetrazol-5-yl)...)
Show SMILES CCCCc1nc(C)n(Cc2occc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C29H28N6O4/c1-3-4-9-25-24(28(36)35(18(2)30-25)17-26-23(29(37)38)14-15-39-26)16-19-10-12-20(13-11-19)21-7-5-6-8-22(21)27-31-33-34-32-27/h5-8,10-15H,3-4,9,16-17H2,1-2H3,(H,37,38)(H,31,32,33,34)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029905
PNG
(4'-(2-Butyl-4-methyl-6-oxo-6H-pyrimidin-1-ylmethyl...)
Show SMILES CCCCc1nc(C)cc(=O)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C23H24N2O3/c1-3-4-9-21-24-16(2)14-22(26)25(21)15-17-10-12-18(13-11-17)19-7-5-6-8-20(19)23(27)28/h5-8,10-14H,3-4,9,15H2,1-2H3,(H,27,28)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029899
PNG
(3-{4-Butyl-2-methyl-6-oxo-5-[2'-(1H-tetrazol-5-yl)...)
Show SMILES CCCCc1nc(C)n(Cc2ccsc2C(=O)OC)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C30H30N6O3S/c1-4-5-10-26-25(29(37)36(19(2)31-26)18-22-15-16-40-27(22)30(38)39-3)17-20-11-13-21(14-12-20)23-8-6-7-9-24(23)28-32-34-35-33-28/h6-9,11-16H,4-5,10,17-18H2,1-3H3,(H,32,33,34,35)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029908
PNG
(4'-(4-Butyl-6-oxo-1-thiophen-2-ylmethyl-1,6-dihydr...)
Show SMILES CCCCc1ncn(Cc2cccs2)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C27H26N2O3S/c1-2-3-10-25-24(26(30)29(18-28-25)17-21-7-6-15-33-21)16-19-11-13-20(14-12-19)22-8-4-5-9-23(22)27(31)32/h4-9,11-15,18H,2-3,10,16-17H2,1H3,(H,31,32)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029893
PNG
(2-[4-Butyl-5-(2'-carboxy-biphenyl-4-ylmethyl)-2-me...)
Show SMILES CCCCc1nc(C)n(Cc2occc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C29H28N2O6/c1-3-4-9-25-24(27(32)31(18(2)30-25)17-26-23(29(35)36)14-15-37-26)16-19-10-12-20(13-11-19)21-7-5-6-8-22(21)28(33)34/h5-8,10-15H,3-4,9,16-17H2,1-2H3,(H,33,34)(H,35,36)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029906
PNG
(2-[4-Butyl-5-(2'-carboxy-biphenyl-4-ylmethyl)-2-me...)
Show SMILES CCCCc1nc(C)n(Cc2sccc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C29H28N2O5S/c1-3-4-9-25-24(27(32)31(18(2)30-25)17-26-23(29(35)36)14-15-37-26)16-19-10-12-20(13-11-19)21-7-5-6-8-22(21)28(33)34/h5-8,10-15H,3-4,9,16-17H2,1-2H3,(H,33,34)(H,35,36)
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Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50029910
PNG
(4'-(4-Butyl-6-oxo-1,6-dihydro-pyrimidin-5-ylmethyl...)
Show SMILES CCCCc1nc[nH]c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C22H22N2O3/c1-2-3-8-20-19(21(25)24-14-23-20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22(26)27/h4-7,9-12,14H,2-3,8,13H2,1H3,(H,26,27)(H,23,24,25)
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>4n/an/an/an/an/an/an/an/a



Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive


J Med Chem 38: 4806-20 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50292633
PNG
(4'-{[2-n-propyl-4-methyl-6-(1-methylbenzoimidazol-...)
Show SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C1=NCCN1)-c1nc2ccccc2n1C
Show InChI InChI=1S/C35H34N6/c1-4-9-32-39-33-23(2)20-26(35-38-29-12-7-8-13-30(29)40(35)3)21-31(33)41(32)22-24-14-16-25(17-15-24)27-10-5-6-11-28(27)34-36-18-19-37-34/h5-8,10-17,20-21H,4,9,18-19,22H2,1-3H3,(H,36,37)
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n/an/a 2.90n/an/an/an/an/an/a



The M. S. University of Baroda

Curated by ChEMBL


Assay Description
Displacement of radiolabeled angiotensin 2 from angiotensin AT1 receptor in bovine adrenal cortex membranes


Bioorg Med Chem 18: 8418-56 (2010)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50282823
PNG
(2-Butyl-6-(1-hydroxy-1-methyl-2-pyrrolidin-2-yl-et...)
Show SMILES CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(O)C[C@H]1CCCN1
Show InChI InChI=1S/C33H37N7O2/c1-3-4-11-30-35-29-17-16-24(33(2,42)20-25-8-7-18-34-25)19-28(29)32(41)40(30)21-22-12-14-23(15-13-22)26-9-5-6-10-27(26)31-36-38-39-37-31/h5-6,9-10,12-17,19,25,34,42H,3-4,7-8,11,18,20-21H2,1-2H3,(H,36,37,38,39)/t25-,33?/m1/s1
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n/an/a 3.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for in vitro for AII receptor antagonistic activity in bovine adrenal cortex.


Bioorg Med Chem Lett 4: 1709-1714 (1994)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50285173
PNG
(2-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-...)
Show SMILES CCCc1cc(=O)n(CCN2C(=O)c3ccccc3C2=O)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C31H27N7O4/c1-2-7-22-18-27(39)36(16-17-37-29(40)25-10-5-6-11-26(25)30(37)41)31(42)38(22)19-20-12-14-21(15-13-20)23-8-3-4-9-24(23)28-32-34-35-33-28/h3-6,8-15,18H,2,7,16-17,19H2,1H3,(H,32,33,34,35)
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n/an/a 4.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex


Bioorg Med Chem Lett 5: 2071-2076 (1995)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049128
PNG
(5-(1-Hydroxy-ethyl)-2-propyl-3-[2'-(2H-tetrazol-5-...)
Show SMILES CCCc1nc(C(C)O)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H24N6O3/c1-3-6-19-24-20(14(2)30)21(23(31)32)29(19)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)22-25-27-28-26-22/h4-5,7-12,14,30H,3,6,13H2,1-2H3,(H,31,32)(H,25,26,27,28)
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n/an/a 4.90n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049118
PNG
(2-Ethyl-5-(1-hydroxy-1-methyl-ethyl)-3-[2'-(2H-tet...)
Show SMILES CCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O
Show InChI InChI=1S/C23H24N6O3/c1-4-18-24-20(23(2,3)32)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-7-5-6-8-17(16)21-25-27-28-26-21/h5-12,32H,4,13H2,1-3H3,(H,30,31)(H,25,26,27,28)
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n/an/a 5.30n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50209823
PNG
(3-(4-(2-(1H-tetrazol-5-yl)-1H-pyrrol-1-yl)benzyl)-...)
Show SMILES CCCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-n1cccc1-c1nnn[nH]1
Show InChI InChI=1S/C24H23N7O2/c1-2-3-9-21-25-19-7-4-6-18(24(32)33)22(19)31(21)15-16-10-12-17(13-11-16)30-14-5-8-20(30)23-26-28-29-27-23/h4-8,10-14H,2-3,9,15H2,1H3,(H,32,33)(H,26,27,28,29)
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n/an/a 6.90n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]angiotensin-2 from bovine adrenal cortex AT1 receptor


Bioorg Med Chem Lett 17: 2921-6 (2007)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049123
PNG
(5-Hydroxymethyl-2-propyl-3-[2'-(2H-tetrazol-5-yl)-...)
Show SMILES CCCc1nc(CO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C22H22N6O3/c1-2-5-19-23-18(13-29)20(22(30)31)28(19)12-14-8-10-15(11-9-14)16-6-3-4-7-17(16)21-24-26-27-25-21/h3-4,6-11,29H,2,5,12-13H2,1H3,(H,30,31)(H,24,25,26,27)
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n/an/a 6.90n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50241364
PNG
(4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-te...)
Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O
Show InChI InChI=1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)
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n/an/a 7.70n/an/an/an/an/an/a



The M. S. University of Baroda

Curated by ChEMBL


Assay Description
Displacement of radiolabeled angiotensin 2 from angiotensin AT1 receptor in bovine adrenal cortex membranes


Bioorg Med Chem 18: 8418-56 (2010)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50241364
PNG
(4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-te...)
Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O
Show InChI InChI=1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)
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n/an/a 8.10n/an/an/an/an/an/a



The M. S. University of Baroda

Curated by ChEMBL


Assay Description
Binding affinity to angiotensin AT1 receptor in bovine adrenal cortex membranes


Bioorg Med Chem 18: 8418-56 (2010)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50241364
PNG
(4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-te...)
Show SMILES CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O
Show InChI InChI=1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)
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n/an/a 8.10n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387812
PNG
(CHEMBL2058372)
Show SMILES CCCCc1nc2ccc(OC)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C30H32N4O4S/c1-5-6-11-29-31-26-17-16-24(37-4)18-27(26)34(29)19-22-12-14-23(15-13-22)25-9-7-8-10-28(25)39(35,36)33-30-20(2)21(3)32-38-30/h7-10,12-18,33H,5-6,11,19H2,1-4H3
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n/an/a 8.5n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387811
PNG
(CHEMBL2058371)
Show SMILES CCCCc1nc2ccc(C)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C30H32N4O3S/c1-5-6-11-29-31-26-17-12-20(2)18-27(26)34(29)19-23-13-15-24(16-14-23)25-9-7-8-10-28(25)38(35,36)33-30-21(3)22(4)32-37-30/h7-10,12-18,33H,5-6,11,19H2,1-4H3
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n/an/a 9.10n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049107
PNG
(2-Propyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Show SMILES CCCc1ncc(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C21H20N6O2/c1-2-5-19-22-12-18(21(28)29)27(19)13-14-8-10-15(11-9-14)16-6-3-4-7-17(16)20-23-25-26-24-20/h3-4,6-12H,2,5,13H2,1H3,(H,28,29)(H,23,24,25,26)
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n/an/a 9.10n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50285171
PNG
(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-bip...)
Show SMILES CCCc1cc(=O)n(CC(=O)N(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H27N7O3/c1-4-7-19-14-22(33)32(16-23(34)30(2)3)25(35)31(19)15-17-10-12-18(13-11-17)20-8-5-6-9-21(20)24-26-28-29-27-24/h5-6,8-14H,4,7,15-16H2,1-3H3,(H,26,27,28,29)
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n/an/a 9.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex


Bioorg Med Chem Lett 5: 2071-2076 (1995)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049109
PNG
(2-Butyl-5-(1-hydroxy-1-methyl-ethyl)-3-[2'-(2H-tet...)
Show SMILES CCCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O
Show InChI InChI=1S/C25H28N6O3/c1-4-5-10-20-26-22(25(2,3)34)21(24(32)33)31(20)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)23-27-29-30-28-23/h6-9,11-14,34H,4-5,10,15H2,1-3H3,(H,32,33)(H,27,28,29,30)
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n/an/a 9.5n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50209824
PNG
(CHEMBL245444 | methyl 3-(4-(2-(1H-tetrazol-5-yl)-1...)
Show SMILES CCCCc1nc2cccc(C(=O)OC)c2n1Cc1ccc(cc1)-n1cccc1-c1nnn[nH]1
Show InChI InChI=1S/C25H25N7O2/c1-3-4-10-22-26-20-8-5-7-19(25(33)34-2)23(20)32(22)16-17-11-13-18(14-12-17)31-15-6-9-21(31)24-27-29-30-28-24/h5-9,11-15H,3-4,10,16H2,1-2H3,(H,27,28,29,30)
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n/an/a 9.80n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]angiotensin-2 from bovine adrenal cortex AT1 receptor


Bioorg Med Chem Lett 17: 2921-6 (2007)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387805
PNG
(CHEMBL2058373)
Show SMILES CCCCc1nc2ccc(Cl)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C29H29ClN4O3S/c1-4-5-10-28-31-25-16-15-23(30)17-26(25)34(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)38(35,36)33-29-19(2)20(3)32-37-29/h6-9,11-17,33H,4-5,10,18H2,1-3H3
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n/an/a 9.80n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387810
PNG
(CHEMBL2058370)
Show SMILES CCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C29H30N4O3S/c1-4-5-14-28-30-25-11-7-8-12-26(25)33(28)19-22-15-17-23(18-16-22)24-10-6-9-13-27(24)37(34,35)32-29-20(2)21(3)31-36-29/h6-13,15-18,32H,4-5,14,19H2,1-3H3
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n/an/a 9.90n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387813
PNG
(CHEMBL2058374)
Show SMILES CCCCc1nc2ccc(Br)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C29H29BrN4O3S/c1-4-5-10-28-31-25-16-15-23(30)17-26(25)34(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)38(35,36)33-29-19(2)20(3)32-37-29/h6-9,11-17,33H,4-5,10,18H2,1-3H3
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n/an/a 10n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387814
PNG
(CHEMBL2058375)
Show SMILES CCCCc1nc2ccc(F)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C29H29FN4O3S/c1-4-5-10-28-31-25-16-15-23(30)17-26(25)34(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)38(35,36)33-29-19(2)20(3)32-37-29/h6-9,11-17,33H,4-5,10,18H2,1-3H3
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n/an/a 10.5n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049200
PNG
(2-Ethyl-5,7-dimethyl-3-[9-(1H-tetrazol-5-ylmethyl)...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc-2c(c1)C(Cc1nnn[nH]1)c1ccccc-21
Show InChI InChI=1S/C26H25N7/c1-4-24-28-25-15(2)11-16(3)27-26(25)33(24)14-17-9-10-20-18-7-5-6-8-19(18)22(21(20)12-17)13-23-29-31-32-30-23/h5-12,22H,4,13-14H2,1-3H3,(H,29,30,31,32)
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n/an/a 11n/an/an/an/an/an/a



The M. S. University of Baroda

Curated by ChEMBL


Assay Description
Binding affinity to angiotensin AT1 receptor in bovine adrenal cortex membranes


Bioorg Med Chem 18: 8418-56 (2010)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387815
PNG
(CHEMBL2058376)
Show SMILES CCCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)C(F)(F)F
Show InChI InChI=1S/C30H29F3N4O3S/c1-4-5-10-28-34-25-16-15-23(30(31,32)33)17-26(25)37(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)41(38,39)36-29-19(2)20(3)35-40-29/h6-9,11-17,36H,4-5,10,18H2,1-3H3
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n/an/a 11n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049200
PNG
(2-Ethyl-5,7-dimethyl-3-[9-(1H-tetrazol-5-ylmethyl)...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc-2c(c1)C(Cc1nnn[nH]1)c1ccccc-21
Show InChI InChI=1S/C26H25N7/c1-4-24-28-25-15(2)11-16(3)27-26(25)33(24)14-17-9-10-20-18-7-5-6-8-19(18)22(21(20)12-17)13-23-29-31-32-30-23/h5-12,22H,4,13-14H2,1-3H3,(H,29,30,31,32)
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n/an/a 11n/an/an/an/an/an/a



DuPont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
In vitro antagonistic potency against Angiotensin II receptor, type 1 in rat adrenal cortex


J Med Chem 39: 625-56 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049124
PNG
(5-Methyl-2-propyl-3-[2'-(1H-tetrazol-5-yl)-bipheny...)
Show SMILES CCCc1nc(C)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C22H22N6O2/c1-3-6-19-23-14(2)20(22(29)30)28(19)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)21-24-26-27-25-21/h4-5,7-12H,3,6,13H2,1-2H3,(H,29,30)(H,24,25,26,27)
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n/an/a 11n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387816
PNG
(CHEMBL2058377)
Show SMILES CCCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)[N+]([O-])=O
Show InChI InChI=1S/C29H29N5O5S/c1-4-5-10-28-30-25-16-15-23(34(35)36)17-26(25)33(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)40(37,38)32-29-19(2)20(3)31-39-29/h6-9,11-17,32H,4-5,10,18H2,1-3H3
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n/an/a 12n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50049116
PNG
(5-Ethyl-2-propyl-3-(2'-tetrazol-1-yl-biphenyl-4-yl...)
Show SMILES CCCc1nc(CC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H24N6O2/c1-3-7-20-24-19(4-2)21(23(30)31)29(20)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-25-27-28-26-22/h5-6,8-13H,3-4,7,14H2,1-2H3,(H,30,31)(H,25,26,27,28)
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n/an/a 12n/an/an/an/an/an/a



Sankyo Company, Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortex


J Med Chem 39: 323-38 (1996)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50285170
PNG
(CHEMBL62314 | N-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-t...)
Show SMILES CCCc1cc(=O)n(CCNC(=O)C(c2ccccc2)c2ccccc2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C37H35N7O3/c1-2-11-30-24-33(45)43(23-22-38-36(46)34(28-12-5-3-6-13-28)29-14-7-4-8-15-29)37(47)44(30)25-26-18-20-27(21-19-26)31-16-9-10-17-32(31)35-39-41-42-40-35/h3-10,12-21,24,34H,2,11,22-23,25H2,1H3,(H,38,46)(H,39,40,41,42)
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n/an/a 14n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for binding affinity against angiotensin II receptor in rat adrenal cortex


Bioorg Med Chem Lett 5: 2071-2076 (1995)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50285172
PNG
(3-Butyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Show SMILES CCCCn1c(=O)cc(CCC)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=O
Show InChI InChI=1S/C25H28N6O2/c1-3-5-15-30-23(32)16-20(8-4-2)31(25(30)33)17-18-11-13-19(14-12-18)21-9-6-7-10-22(21)24-26-28-29-27-24/h6-7,9-14,16H,3-5,8,15,17H2,1-2H3,(H,26,27,28,29)
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n/an/a 16n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for binding affinity against angiotensin II receptor in bovine adrenal cortex


Bioorg Med Chem Lett 5: 2071-2076 (1995)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50387809
PNG
(CHEMBL2058369)
Show SMILES CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C
Show InChI InChI=1S/C28H28N4O3S/c1-4-9-27-29-24-11-6-7-12-25(24)32(27)18-21-14-16-22(17-15-21)23-10-5-8-13-26(23)36(33,34)31-28-19(2)20(3)30-35-28/h5-8,10-17,31H,4,9,18H2,1-3H3
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n/an/a 16n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]AngII from type 1 angiotensin 2 receptor in bovine adrenal cortex


Bioorg Med Chem 20: 4661-7 (2012)

More data for this
Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50209827
PNG
(3-(4-(2-(1H-tetrazol-5-yl)-1H-pyrrol-1-yl)benzyl)-...)
Show SMILES CCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-n1cccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H21N7O2/c1-2-5-20-24-18-7-3-6-17(23(31)32)21(18)30(20)14-15-9-11-16(12-10-15)29-13-4-8-19(29)22-25-27-28-26-22/h3-4,6-13H,2,5,14H2,1H3,(H,31,32)(H,25,26,27,28)
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n/an/a 16n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Displacement of [125I]angiotensin-2 from bovine adrenal cortex AT1 receptor


Bioorg Med Chem Lett 17: 2921-6 (2007)

More data for this
Ligand-Target Pair
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