Compile Data Set for Download or QSAR

Found 2296 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50016673 (CHEMBL52896 | N-Hydroxy-N-methyl-2-[4-(quinolin-2-...) Show SMILES CN(O)C(=O)Cc1ccc(OCc2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C19H18N2O3/c1-21(23)19(22)12-14-6-10-17(11-7-14)24-13-16-9-8-15-4-2-3-5-18(15)20-16/h2-11,23H,12-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) Article DOI: 10.1021/jm00128a027 BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50043670 (2-{(S)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...) Show SMILES CC[C@@](OC)(c1nccs1)c1cc(F)cc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C24H22FNO2S/c1-3-24(27-2,23-26-10-11-29-23)20-13-21(25)15-22(14-20)28-16-17-8-9-18-6-4-5-7-19(18)12-17/h4-15H,3,16H2,1-2H3/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from mouse macrophage				J Med Chem 37: 113-24 (1994) Article DOI: 10.1021/jm00027a014 BindingDB Entry DOI: 10.7270/Q2JW8CZP
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50043682 ((R)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...) Show SMILES CC[C@](OC)(C(=O)OC)c1cc(F)cc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C23H23FO4/c1-4-23(27-3,22(25)26-2)19-12-20(24)14-21(13-19)28-15-16-9-10-17-7-5-6-8-18(17)11-16/h5-14H,4,15H2,1-3H3/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from mouse macrophage				J Med Chem 37: 113-24 (1994) Article DOI: 10.1021/jm00027a014 BindingDB Entry DOI: 10.7270/Q2JW8CZP
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50406364 (CHEMBL173711) Show SMILES CC(C)Cc1ccc(cc1)C(Cc1ccccc1)C(=O)N(C)O Show InChI InChI=1S/C20H25NO2/c1-15(2)13-17-9-11-18(12-10-17)19(20(22)21(3)23)14-16-7-5-4-6-8-16/h4-12,15,19,23H,13-14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)				J Med Chem 33: 992-8 (1990) Article DOI: 10.1021/jm00165a017 BindingDB Entry DOI: 10.7270/Q2WW7GNM
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50406363 (CHEMBL69795) Show SMILES CC(C)Cc1ccc(cc1)C(C(C)C)C(=O)N(C)O Show InChI InChI=1S/C16H25NO2/c1-11(2)10-13-6-8-14(9-7-13)15(12(3)4)16(18)17(5)19/h6-9,11-12,15,19H,10H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)				J Med Chem 33: 992-8 (1990) Article DOI: 10.1021/jm00165a017 BindingDB Entry DOI: 10.7270/Q2WW7GNM
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50043669 (6-[3-Fluoro-5-((S)-1-methoxy-1-thiazol-2-yl-propyl...) Show SMILES CC[C@@](OC)(c1nccs1)c1cc(F)cc(OCc2ccc3n(C)c(=O)ccc3c2)c1 Show InChI InChI=1S/C24H23FN2O3S/c1-4-24(29-3,23-26-9-10-31-23)18-12-19(25)14-20(13-18)30-15-16-5-7-21-17(11-16)6-8-22(28)27(21)2/h5-14H,4,15H2,1-3H3/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from mouse macrophage				J Med Chem 37: 113-24 (1994) Article DOI: 10.1021/jm00027a014 BindingDB Entry DOI: 10.7270/Q2JW8CZP
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042977 (1-(2,5-Diethoxy-phenyl)-3-(3,4-dihydroxy-phenyl)-p...) Show SMILES CCOc1ccc(OCC)c(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C19H20O5/c1-3-23-14-7-10-19(24-4-2)15(12-14)16(20)8-5-13-6-9-17(21)18(22)11-13/h5-12,21-22H,3-4H2,1-2H3/b8-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042951 (3-(3,4-Dihydroxy-phenyl)-1-(5-ethoxy-2-methoxy-phe...) Show SMILES CCOc1ccc(OC)c(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H18O5/c1-3-23-13-6-9-18(22-2)14(11-13)15(19)7-4-12-5-8-16(20)17(21)10-12/h4-11,20-21H,3H2,1-2H3/b7-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042962 ((E)-3-(3,4-Dihydroxy-phenyl)-1-(4-hydroxy-phenyl)-...) Show SMILES Oc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H12O4/c16-12-5-3-11(4-6-12)13(17)7-1-10-2-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042981 (3-(3,4-Dihydroxy-phenyl)-1-(2-hydroxy-5-isopropyl-...) Show SMILES CC(C)c1ccc(O)c(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H18O4/c1-11(2)13-5-8-16(20)14(10-13)15(19)6-3-12-4-7-17(21)18(22)9-12/h3-11,20-22H,1-2H3/b6-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042962 ((E)-3-(3,4-Dihydroxy-phenyl)-1-(4-hydroxy-phenyl)-...) Show SMILES Oc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H12O4/c16-12-5-3-11(4-6-12)13(17)7-1-10-2-8-14(18)15(19)9-10/h1-9,16,18-19H/b7-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 5-lipoxygenase in rat RBL1 cells				Citation and Details Article DOI: 10.1007/s00044-013-0745-7 BindingDB Entry DOI: 10.7270/Q22N53QB
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042979 (3-(3,4-Dihydroxy-phenyl)-1-(3-hydroxy-phenyl)-prop...) Show SMILES Oc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H12O4/c16-12-3-1-2-11(9-12)13(17)6-4-10-5-7-14(18)15(19)8-10/h1-9,16,18-19H/b6-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042979 (3-(3,4-Dihydroxy-phenyl)-1-(3-hydroxy-phenyl)-prop...) Show SMILES Oc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H12O4/c16-12-3-1-2-11(9-12)13(17)6-4-10-5-7-14(18)15(19)8-10/h1-9,16,18-19H/b6-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 5-lipoxygenase in rat RBL1 cells				Citation and Details Article DOI: 10.1007/s00044-013-0745-7 BindingDB Entry DOI: 10.7270/Q22N53QB
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50406422 (CHEMBL2115381) Show SMILES CCCCCCCCCCCCCCCCCCOC1C(=O)O[C@H](C(O)CO)C1=O Show InChI InChI=1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-29-23-21(27)22(20(26)19-25)30-24(23)28/h20,22-23,25-26H,2-19H2,1H3/t20?,22-,23?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description Reduction of lipid peroxide formed in rat brain homogenates.				J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042949 ((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...) Show SMILES Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1 Show InChI InChI=1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042949 ((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...) Show SMILES Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1 Show InChI InChI=1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 5-lipoxygenase in rat RBL1 cells				Citation and Details Article DOI: 10.1007/s00044-013-0745-7 BindingDB Entry DOI: 10.7270/Q22N53QB
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042964 (3-(3,4-Dihydroxy-phenyl)-1-(4-dimethylamino-phenyl...) Show SMILES CN(C)c1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H17NO3/c1-18(2)14-7-5-13(6-8-14)15(19)9-3-12-4-10-16(20)17(21)11-12/h3-11,20-21H,1-2H3/b9-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50043677 ((S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...) Show SMILES CC[C@@](OC)(C(=O)OC)c1cc(F)cc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C23H23FO4/c1-4-23(27-3,22(25)26-2)19-12-20(24)14-21(13-19)28-15-16-9-10-17-7-5-6-8-18(17)11-16/h5-14H,4,15H2,1-3H3/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from mouse macrophage				J Med Chem 37: 113-24 (1994) Article DOI: 10.1021/jm00027a014 BindingDB Entry DOI: 10.7270/Q2JW8CZP
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50000832 (2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...) Show SMILES COC(C)(c1nccs1)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in mouse macrophages.				J Med Chem 34: 2176-86 (1991) Article DOI: 10.1021/jm00111a038 BindingDB Entry DOI: 10.7270/Q2S46QX6
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50006805 (3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...) Show SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c2c1 Show InChI InChI=1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description The compound was tested for inhibitory activity against 5-lipoxygenase translocation inhibitor in rat RBL-2H3 cells				J Med Chem 35: 2501-24 (1992) Article DOI: 10.1021/jm00092a001 BindingDB Entry DOI: 10.7270/Q23B60R4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50283416 (4-[7-(2,3-Dihydroxy-phenyl)-heptyloxy]-2-hydroxy-3...) Show SMILES CCCc1c(O)c(ccc1OCCCCCCCc1cccc(O)c1O)C(O)=O Show InChI InChI=1S/C23H30O6/c1-2-9-17-20(14-13-18(22(17)26)23(27)28)29-15-7-5-3-4-6-10-16-11-8-12-19(24)21(16)25/h8,11-14,24-26H,2-7,9-10,15H2,1H3,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells				Bioorg Med Chem Lett 4: 339-344 (1994) Article DOI: 10.1016/S0960-894X(01)80140-2 BindingDB Entry DOI: 10.7270/Q2W095WT
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042971 (3-(3,4-Dihydroxy-phenyl)-1-(5-ethoxy-2-hydroxy-phe...) Show SMILES CCOc1ccc(O)c(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H16O5/c1-2-22-12-5-8-15(19)13(10-12)14(18)6-3-11-4-7-16(20)17(21)9-11/h3-10,19-21H,2H2,1H3/b6-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50007052 (1-[3-(3-Phenyl-allyloxy)-phenyl]-1-thiazol-2-yl-pr...) Show SMILES CCC(O)(c1nccs1)c1cccc(OC\C=C\c2ccccc2)c1 Show InChI InChI=1S/C21H21NO2S/c1-2-21(23,20-22-13-15-25-20)18-11-6-12-19(16-18)24-14-7-10-17-8-4-3-5-9-17/h3-13,15-16,23H,2,14H2,1H3/b10-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in mouse macrophages.				J Med Chem 34: 2176-86 (1991) Article DOI: 10.1021/jm00111a038 BindingDB Entry DOI: 10.7270/Q2S46QX6
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50283408 (4-[5-(2,3-Dihydroxy-phenyl)-pentyloxy]-2-hydroxy-3...) Show SMILES CCCc1c(O)c(ccc1OCCCCCc1cccc(O)c1O)C(O)=O Show InChI InChI=1S/C21H26O6/c1-2-7-15-18(12-11-16(20(15)24)21(25)26)27-13-5-3-4-8-14-9-6-10-17(22)19(14)23/h6,9-12,22-24H,2-5,7-8,13H2,1H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells				Bioorg Med Chem Lett 4: 339-344 (1994) Article DOI: 10.1016/S0960-894X(01)80140-2 BindingDB Entry DOI: 10.7270/Q2W095WT
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042945 (3-(3,4-Dihydroxy-phenyl)-1-(3-methoxy-phenyl)-prop...) Show SMILES COc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14O4/c1-20-13-4-2-3-12(10-13)14(17)7-5-11-6-8-15(18)16(19)9-11/h2-10,18-19H,1H3/b7-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50004679 (2-Benzyl-naphthalen-1-ol | 2-Benzyl-naphthalen-1-o...) Show SMILES Oc1c(Cc2ccccc2)ccc2ccccc12 Show InChI InChI=1S/C17H14O/c18-17-15(12-13-6-2-1-3-7-13)11-10-14-8-4-5-9-16(14)17/h1-11,18H,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042968 (3-(3,4-Dihydroxy-phenyl)-1-(2,5-dimethoxy-phenyl)-...) Show SMILES COc1ccc(OC)c(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H16O5/c1-21-12-5-8-17(22-2)13(10-12)14(18)6-3-11-4-7-15(19)16(20)9-11/h3-10,19-20H,1-2H3/b6-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50010968 (3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...) Show SMILES CCOC(=O)C=Cc1c(O)c(=C)c(Cc2cccnc2)c(O)c1=C Show InChI InChI=1S/C19H19NO4/c1-4-24-17(21)8-7-15-12(2)19(23)16(13(3)18(15)22)10-14-6-5-9-20-11-14/h5-9,11,22-23H,2-4,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries, Ltd. Curated by ChEMBL					Assay Description The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells				J Med Chem 34: 267-76 (1991) Article DOI: 10.1021/jm00105a042 BindingDB Entry DOI: 10.7270/Q2SN07X9
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50000534 (2-Phenethyl-6-[3-(pyridin-4-ylsulfanyl)-propyl]-2,...) Show SMILES Oc1cc2CC(CCc3ccccc3)Oc2cc1CCCSc1ccncc1 Show InChI InChI=1S/C24H25NO2S/c26-23-16-20-15-21(9-8-18-5-2-1-3-6-18)27-24(20)17-19(23)7-4-14-28-22-10-12-25-13-11-22/h1-3,5-6,10-13,16-17,21,26H,4,7-9,14-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL					Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.				J Med Chem 35: 1299-318 (1992) Article DOI: 10.1021/jm00085a019 BindingDB Entry DOI: 10.7270/Q25X27WS
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50000857 (2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...) Show SMILES CCC(OC)(c1nccs1)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-13-14-28-23)21-9-6-10-22(16-21)27-17-18-11-12-19-7-4-5-8-20(19)15-18/h4-16H,3,17H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in mouse macrophages.				J Med Chem 34: 2176-86 (1991) Article DOI: 10.1021/jm00111a038 BindingDB Entry DOI: 10.7270/Q2S46QX6
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042973 (1-(4-Chloro-phenyl)-3-(3,4-dihydroxy-phenyl)-prope...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(Cl)cc2)cc1O Show InChI InChI=1S/C15H11ClO3/c16-12-5-3-11(4-6-12)13(17)7-1-10-2-8-14(18)15(19)9-10/h1-9,18-19H/b7-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50025312 (2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-6-(3-...) Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OCCC(C)C)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C21H22O7/c1-11(2)6-7-27-21-18(26-3)10-17-19(20(21)25)15(24)9-16(28-17)12-4-5-13(22)14(23)8-12/h4-5,8-11,22-23,25H,6-7H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells.				J Med Chem 29: 2256-62 (1986) Article DOI: 10.1021/jm00161a021 BindingDB Entry DOI: 10.7270/Q2M907P5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042991 (3-(3,4-Dihydroxy-phenyl)-1-(4-hydroxy-3-methoxy-ph...) Show SMILES COc1cc(ccc1O)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H14O5/c1-21-16-9-11(4-7-14(16)19)12(17)5-2-10-3-6-13(18)15(20)8-10/h2-9,18-20H,1H3/b5-2+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50043666 ((R)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...) Show SMILES CC[C@](OC)(C(=O)OC)c1cc(F)cc(OCc2ccc3n(C)c(=O)ccc3c2)c1 Show InChI InChI=1S/C23H24FNO5/c1-5-23(29-4,22(27)28-3)17-11-18(24)13-19(12-17)30-14-15-6-8-20-16(10-15)7-9-21(26)25(20)2/h6-13H,5,14H2,1-4H3/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from mouse macrophage				J Med Chem 37: 113-24 (1994) Article DOI: 10.1021/jm00027a014 BindingDB Entry DOI: 10.7270/Q2JW8CZP
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042960 (3-(3,4-Dihydroxy-phenyl)-1-(3-dimethylamino-phenyl...) Show SMILES CN(C)c1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H17NO3/c1-18(2)14-5-3-4-13(11-14)15(19)8-6-12-7-9-16(20)17(21)10-12/h3-11,20-21H,1-2H3/b8-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50076649 (CHEMBL369848 | N-{1-methyl-3-[1-(4-methoxyphenyl)-...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(N)=O Show InChI InChI=1S/C21H19ClN4O3/c1-14(26(28)21(23)27)3-8-17-13-20(15-4-6-16(22)7-5-15)25(24-17)18-9-11-19(29-2)12-10-18/h4-7,9-14,28H,1-2H3,(H2,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) Article DOI: 10.1016/s0960-894x(99)00117-1 BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM22372 (4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...) Show SMILES C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells				Bioorg Med Chem Lett 4: 339-344 (1994) Article DOI: 10.1016/S0960-894X(01)80140-2 BindingDB Entry DOI: 10.7270/Q2W095WT
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042950 (3-(3,4-Dihydroxy-phenyl)-1-(2,4-dimethoxy-phenyl)-...) Show SMILES COc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(OC)c1 Show InChI InChI=1S/C17H16O5/c1-21-12-5-6-13(17(10-12)22-2)14(18)7-3-11-4-8-15(19)16(20)9-11/h3-10,19-20H,1-2H3/b7-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50048999 (CHEMBL82292 | N-Hydroxy-N-methyl-3-(11-oxo-6,11-di...) Show SMILES CN(O)C(=O)CCc1ccc2OCc3ccccc3C(=O)c2c1 Show InChI InChI=1S/C18H17NO4/c1-19(22)17(20)9-7-12-6-8-16-15(10-12)18(21)14-5-3-2-4-13(14)11-23-16/h2-6,8,10,22H,7,9,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant				J Med Chem 39: 246-52 (1996) Article DOI: 10.1021/jm950563z BindingDB Entry DOI: 10.7270/Q22806PF
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Rattus norvegicus)	BDBM50052018 (3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...) Show SMILES CC(C)(C)Sc1c(CC(C)(C)C([O-])=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12 Show InChI InChI=1S/C34H35ClN2O3S/c1-33(2,3)41-31-27-18-26(40-21-25-15-12-23-8-6-7-9-28(23)36-25)16-17-29(27)37(20-22-10-13-24(35)14-11-22)30(31)19-34(4,5)32(38)39/h6-18H,19-21H2,1-5H3,(H,38,39)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amira Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of FLAP in rat whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 4 hrs by ELISA				J Med Chem 54: 8013-29 (2011) Article DOI: 10.1021/jm2008369 BindingDB Entry DOI: 10.7270/Q269740W
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50025315 (2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-6-oct...) Show SMILES CCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C24H28O7/c1-3-4-5-6-7-8-11-30-24-21(29-2)14-20-22(23(24)28)18(27)13-19(31-20)15-9-10-16(25)17(26)12-15/h9-10,12-14,25-26,28H,3-8,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells.				J Med Chem 29: 2256-62 (1986) Article DOI: 10.1021/jm00161a021 BindingDB Entry DOI: 10.7270/Q2M907P5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012730 (5-(1-Hydroxy-naphthalen-2-yl)-pentanoic acid ethyl...) Show SMILES CCOC(=O)CCCCc1ccc2ccccc2c1O Show InChI InChI=1S/C17H20O3/c1-2-20-16(18)10-6-4-8-14-12-11-13-7-3-5-9-15(13)17(14)19/h3,5,7,9,11-12,19H,2,4,6,8,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
E. I. du Pont de Nemours and Company, Inc. Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell line				J Med Chem 33: 360-70 (1990) Article DOI: 10.1021/jm00163a058 BindingDB Entry DOI: 10.7270/Q2513ZSJ
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042952 (3-(3,4-Dihydroxy-phenyl)-1-(2-hydroxy-5-isopropoxy...) Show SMILES CC(C)Oc1ccc(O)c(c1)C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H18O5/c1-11(2)23-13-5-8-16(20)14(10-13)15(19)6-3-12-4-7-17(21)18(22)9-12/h3-11,20-22H,1-2H3/b6-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50025322 (6-Decyloxy-2-(3,4-dihydroxy-phenyl)-5-hydroxy-7-me...) Show SMILES CCCCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C26H32O7/c1-3-4-5-6-7-8-9-10-13-32-26-23(31-2)16-22-24(25(26)30)20(29)15-21(33-22)17-11-12-18(27)19(28)14-17/h11-12,14-16,27-28,30H,3-10,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells.				J Med Chem 29: 2256-62 (1986) Article DOI: 10.1021/jm00161a021 BindingDB Entry DOI: 10.7270/Q2M907P5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50043678 ((S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...) Show SMILES CC[C@@](OC)(C(=O)OC)c1cc(F)cc(OCc2ccc3n(C)c(=O)ccc3c2)c1 Show InChI InChI=1S/C23H24FNO5/c1-5-23(29-4,22(27)28-3)17-11-18(24)13-19(12-17)30-14-15-6-8-20-16(10-15)7-9-21(26)25(20)2/h6-13H,5,14H2,1-4H3/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from mouse macrophage				J Med Chem 37: 113-24 (1994) Article DOI: 10.1021/jm00027a014 BindingDB Entry DOI: 10.7270/Q2JW8CZP
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50025291 (2-(3,4-Dihydroxy-phenyl)-6-hexyloxy-5,7-dimethoxy-...) Show SMILES CCCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C23H26O7/c1-4-5-6-7-10-29-22-20(27-2)13-19-21(23(22)28-3)17(26)12-18(30-19)14-8-9-15(24)16(25)11-14/h8-9,11-13,24-25H,4-7,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells.				J Med Chem 29: 2256-62 (1986) Article DOI: 10.1021/jm00161a021 BindingDB Entry DOI: 10.7270/Q2M907P5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042953 (3-(3,4-Dihydroxy-phenyl)-1-(5-isopropoxy-2-methoxy...) Show SMILES COc1ccc(OC(C)C)cc1C(=O)\C=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C19H20O5/c1-12(2)24-14-6-9-19(23-3)15(11-14)16(20)7-4-13-5-8-17(21)18(22)10-13/h4-12,21-22H,1-3H3/b7-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50007040 (2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...) Show SMILES COC1(CCc2ccc(OCc3ccc4ccccc4c3)cc12)c1nccs1 Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.				J Med Chem 34: 2176-86 (1991) Article DOI: 10.1021/jm00111a038 BindingDB Entry DOI: 10.7270/Q2S46QX6
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50025286 (2-(3,4-Dihydroxy-phenyl)-5-hexyloxy-6,7-dimethoxy-...) Show SMILES CCCCCCOc1c(OC)c(OC)cc2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C23H26O7/c1-4-5-6-7-10-29-23-21-17(26)12-18(14-8-9-15(24)16(25)11-14)30-19(21)13-20(27-2)22(23)28-3/h8-9,11-13,24-25H,4-7,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells.				J Med Chem 29: 2256-62 (1986) Article DOI: 10.1021/jm00161a021 BindingDB Entry DOI: 10.7270/Q2M907P5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50042972 (3-(3,4-Dihydroxy-phenyl)-1-(2-hydroxy-4-methoxy-ph...) Show SMILES COc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1 Show InChI InChI=1S/C16H14O5/c1-21-11-4-5-12(15(19)9-11)13(17)6-2-10-3-7-14(18)16(20)8-10/h2-9,18-20H,1H3/b6-2+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Tokushima Bunri University Curated by ChEMBL					Assay Description In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined				J Med Chem 36: 3904-9 (1994) Article DOI: 10.1021/jm00076a019 BindingDB Entry DOI: 10.7270/Q2MS3RT4
					More data for this Ligand-Target Pair

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