BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' AND taxid = 9541   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264141
PNG
(1-Benzyl-1H-benzoimidazole-2-carboxylic acid {2-[6...)
Show SMILES O=C(CCNC(=O)c1nc2ccccc2n1Cc1ccccc1)Nc1ccc(nc1)C1=NCCN1
Show InChI InChI=1S/C26H25N7O2/c34-23(31-19-10-11-21(30-16-19)24-27-14-15-28-24)12-13-29-26(35)25-32-20-8-4-5-9-22(20)33(25)17-18-6-2-1-3-7-18/h1-11,16H,12-15,17H2,(H,27,28)(H,29,35)(H,31,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264298
PNG
(CHEMBL490201 | N-(2-((4-(4,5-dihydro-1H-imidazol-2...)
Show SMILES CN(Cc1ccc(cc1)C1=NCCN1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H28N6O2/c1-33(18-21-11-13-22(14-12-21)26-29-15-16-30-26)25(35)17-31-28(36)27-32-23-9-5-6-10-24(23)34(27)19-20-7-3-2-4-8-20/h2-14H,15-19H2,1H3,(H,29,30)(H,31,36)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264140
PNG
(CHEMBL492211 | N-(2-((4-(4,5-dihydro-1H-imidazol-2...)
Show SMILES CCN(CC(=O)N(C)Cc1ccc(cc1)C1=NCCN1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C30H32N6O2/c1-3-35(21-27(37)34(2)19-23-13-15-24(16-14-23)28-31-17-18-32-28)30(38)29-33-25-11-7-8-12-26(25)36(29)20-22-9-5-4-6-10-22/h4-16H,3,17-21H2,1-2H3,(H,31,32)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264589
PNG
(CHEMBL489191 | N-(2-((4-(1-methyl-4,5-dihydro-1H-i...)
Show SMILES CN(Cc1ccc(cc1)C1=NCCN1C)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C29H30N6O2/c1-33-17-16-30-27(33)23-14-12-22(13-15-23)19-34(2)26(36)18-31-29(37)28-32-24-10-6-7-11-25(24)35(28)20-21-8-4-3-5-9-21/h3-15H,16-20H2,1-2H3,(H,31,37)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264368
PNG
(1-benzyl-N-ethyl-N-(2-(4-(1-methylpiperidin-4-yl)p...)
Show SMILES CCN(CC(=O)N1CCN(CC1)C1CCN(C)CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C29H38N6O2/c1-3-32(22-27(36)34-19-17-33(18-20-34)24-13-15-31(2)16-14-24)29(37)28-30-25-11-7-8-12-26(25)35(28)21-23-9-5-4-6-10-23/h4-12,24H,3,13-22H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264370
PNG
(1-benzyl-N-(2-(4-(1-methylpiperidin-4-yl)piperazin...)
Show SMILES CCCN(CC(=O)N1CCN(CC1)C1CCN(C)CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C30H40N6O2/c1-3-15-35(23-28(37)34-20-18-33(19-21-34)25-13-16-32(2)17-14-25)30(38)29-31-26-11-7-8-12-27(26)36(29)22-24-9-5-4-6-10-24/h4-12,25H,3,13-23H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264446
PNG
(CHEMBL489203 | N-(3-((4-(4,5-dihydro-1H-imidazol-2...)
Show SMILES CN(Cc1ccc(cc1)C1=NCCN1)C(=O)CCNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C29H30N6O2/c1-34(19-22-11-13-23(14-12-22)27-30-17-18-31-27)26(36)15-16-32-29(37)28-33-24-9-5-6-10-25(24)35(28)20-21-7-3-2-4-8-21/h2-14H,15-20H2,1H3,(H,30,31)(H,32,37)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264497
PNG
(1-(1-Benzyl-1H-benzoimidazole-2-carbonyl)-piperidi...)
Show SMILES CN(Cc1ccc(cc1)C1=NCCN1)C(=O)C1CCN(CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C32H34N6O2/c1-36(21-24-11-13-25(14-12-24)29-33-17-18-34-29)31(39)26-15-19-37(20-16-26)32(40)30-35-27-9-5-6-10-28(27)38(30)22-23-7-3-2-4-8-23/h2-14,26H,15-22H2,1H3,(H,33,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 188n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264632
PNG
(CHEMBL489810 | N-(2-((4-(piperidin-1-ylmethyl)benz...)
Show SMILES CN(Cc1ccc(CN2CCCCC2)cc1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C31H35N5O2/c1-34(21-25-14-16-26(17-15-25)22-35-18-8-3-9-19-35)29(37)20-32-31(38)30-33-27-12-6-7-13-28(27)36(30)23-24-10-4-2-5-11-24/h2,4-7,10-17H,3,8-9,18-23H2,1H3,(H,32,38)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 196n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264331
PNG
(1-benzyl-N-methyl-N-(2-(4-(1-methylpiperidin-4-yl)...)
Show SMILES CN(CC(=O)N1CCN(CC1)C1CCN(C)CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H36N6O2/c1-30-14-12-23(13-15-30)32-16-18-33(19-17-32)26(35)21-31(2)28(36)27-29-24-10-6-7-11-25(24)34(27)20-22-8-4-3-5-9-22/h3-11,23H,12-21H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 268n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264332
PNG
(1-benzyl-N-ethyl-N-(2-oxo-2-(4-(pyridin-4-yl)piper...)
Show SMILES CCN(CC(=O)N1CCN(CC1)c1ccncc1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H30N6O2/c1-2-31(21-26(35)33-18-16-32(17-19-33)23-12-14-29-15-13-23)28(36)27-30-24-10-6-7-11-25(24)34(27)20-22-8-4-3-5-9-22/h3-15H,2,16-21H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 278n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264296
PNG
(1-benzyl-N-(2-oxo-2-(4-(pyridin-4-yl)piperazin-1-y...)
Show SMILES O=C(CNC(=O)c1nc2ccccc2n1Cc1ccccc1)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C26H26N6O2/c33-24(31-16-14-30(15-17-31)21-10-12-27-13-11-21)18-28-26(34)25-29-22-8-4-5-9-23(22)32(25)19-20-6-2-1-3-7-20/h1-13H,14-19H2,(H,28,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264631
PNG
(CHEMBL522789 | N-(2-((4-(pyrimidin-2-yl)benzyl)(me...)
Show SMILES CN(Cc1ccc(cc1)-c1ncccn1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C29H26N6O2/c1-34(19-22-12-14-23(15-13-22)27-30-16-7-17-31-27)26(36)18-32-29(37)28-33-24-10-5-6-11-25(24)35(28)20-21-8-3-2-4-9-21/h2-17H,18-20H2,1H3,(H,32,37)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264369
PNG
(1-benzyl-N-(2-oxo-2-(4-(pyridin-4-yl)piperazin-1-y...)
Show SMILES CCCN(CC(=O)N1CCN(CC1)c1ccncc1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C29H32N6O2/c1-2-16-34(22-27(36)33-19-17-32(18-20-33)24-12-14-30-15-13-24)29(37)28-31-25-10-6-7-11-26(25)35(28)21-23-8-4-3-5-9-23/h3-15H,2,16-22H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 355n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264630
PNG
(CHEMBL490827 | N-(2-((4-(pyridin-2-yl)benzyl)(meth...)
Show SMILES CN(Cc1ccc(cc1)-c1ccccn1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C30H27N5O2/c1-34(20-23-14-16-24(17-15-23)25-11-7-8-18-31-25)28(36)19-32-30(37)29-33-26-12-5-6-13-27(26)35(29)21-22-9-3-2-4-10-22/h2-18H,19-21H2,1H3,(H,32,37)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 407n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264400
PNG
(1-benzyl-N-isopropyl-N-(2-(4-(1-methylpiperidin-4-...)
Show SMILES CC(C)N(CC(=O)N1CCN(CC1)C1CCN(C)CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C30H40N6O2/c1-23(2)35(22-28(37)34-19-17-33(18-20-34)25-13-15-32(3)16-14-25)30(38)29-31-26-11-7-8-12-27(26)36(29)21-24-9-5-4-6-10-24/h4-12,23,25H,13-22H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 465n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264399
PNG
(1-Benzyl-1H-benzoimidazole-2-carboxylic acid [2-(1...)
Show SMILES O=C(CCNC(=O)c1nc2ccccc2n1Cc1ccccc1)Nc1ccc2cn[nH]c2c1
Show InChI InChI=1S/C25H22N6O2/c32-23(28-19-11-10-18-15-27-30-21(18)14-19)12-13-26-25(33)24-29-20-8-4-5-9-22(20)31(24)16-17-6-2-1-3-7-17/h1-11,14-15H,12-13,16H2,(H,26,33)(H,27,30)(H,28,32)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 524n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264445
PNG
(1-benzyl-N-(3-(4-(1-methylpiperidin-4-yl)piperazin...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)CCNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H36N6O2/c1-31-15-12-23(13-16-31)32-17-19-33(20-18-32)26(35)11-14-29-28(36)27-30-24-9-5-6-10-25(24)34(27)21-22-7-3-2-4-8-22/h2-10,23H,11-21H2,1H3,(H,29,36)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 601n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264591
PNG
(CHEMBL489389 | N-(2-((4-(1H-imidazol-1-yl)benzyl)(...)
Show SMILES CN(Cc1ccc(cc1)-n1ccnc1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H26N6O2/c1-32(18-22-11-13-23(14-12-22)33-16-15-29-20-33)26(35)17-30-28(36)27-31-24-9-5-6-10-25(24)34(27)19-21-7-3-2-4-8-21/h2-16,20H,17-19H2,1H3,(H,30,36)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 626n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264297
PNG
(1-benzyl-N-(2-(4-(1-methylpiperidin-4-yl)piperazin...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C27H34N6O2/c1-30-13-11-22(12-14-30)31-15-17-32(18-16-31)25(34)19-28-27(35)26-29-23-9-5-6-10-24(23)33(26)20-21-7-3-2-4-8-21/h2-10,22H,11-20H2,1H3,(H,28,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 686n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264590
PNG
(CHEMBL489192 | N-(2-((4-(5-methyl-1,2,4-oxadiazol-...)
Show SMILES CN(Cc1ccc(cc1)-c1noc(C)n1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H26N6O3/c1-19-30-26(32-37-19)22-14-12-21(13-15-22)17-33(2)25(35)16-29-28(36)27-31-23-10-6-7-11-24(23)34(27)18-20-8-4-3-5-9-20/h3-15H,16-18H2,1-2H3,(H,29,36)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 718n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264715
PNG
(CHEMBL483653 | N-(3-(3H-benzo[d]imidazol-5-ylamino...)
Show SMILES O=C(CCNC(=O)c1nc2ccccc2n1Cc1ccccc1)Nc1ccc2nc[nH]c2c1
Show InChI InChI=1S/C25H22N6O2/c32-23(29-18-10-11-19-21(14-18)28-16-27-19)12-13-26-25(33)24-30-20-8-4-5-9-22(20)31(24)15-17-6-2-1-3-7-17/h1-11,14,16H,12-13,15H2,(H,26,33)(H,27,28)(H,29,32)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 744n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264531
PNG
((1-Benzyl-1H-benzoimidazol-2-yl)-{(S)-2-[4-(1-meth...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)[C@@H]1CCCN1C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C30H38N6O2/c1-32-16-13-24(14-17-32)33-18-20-34(21-19-33)29(37)27-12-7-15-35(27)30(38)28-31-25-10-5-6-11-26(25)36(28)22-23-8-3-2-4-9-23/h2-6,8-11,24,27H,7,12-22H2,1H3/t27-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 884n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264401
PNG
(1-benzyl-N-(3-oxo-3-(4-(pyridin-4-yl)piperazin-1-y...)
Show SMILES O=C(CCNC(=O)c1nc2ccccc2n1Cc1ccccc1)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C27H28N6O2/c34-25(32-18-16-31(17-19-32)22-10-13-28-14-11-22)12-15-29-27(35)26-30-23-8-4-5-9-24(23)33(26)20-21-6-2-1-3-7-21/h1-11,13-14H,12,15-20H2,(H,29,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 962n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264268
PNG
(CHEMBL523773 | N-(4-(4,5-dihydro-1H-imidazol-2-yl)...)
Show SMILES CN(Cc1ccc(cc1)C1=NCCN1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C26H25N5O/c1-30(17-20-11-13-21(14-12-20)24-27-15-16-28-24)26(32)25-29-22-9-5-6-10-23(22)31(25)18-19-7-3-2-4-8-19/h2-14H,15-18H2,1H3,(H,27,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.02E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264677
PNG
(CHEMBL491041 | N-(2-((4-(thiazol-2-yl)benzyl)(meth...)
Show SMILES CN(Cc1ccc(cc1)-c1nccs1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H25N5O2S/c1-32(18-21-11-13-22(14-12-21)28-29-15-16-36-28)25(34)17-30-27(35)26-31-23-9-5-6-10-24(23)33(26)19-20-7-3-2-4-8-20/h2-16H,17-19H2,1H3,(H,30,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.17E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264330
PNG
(1-benzyl-N-methyl-N-(2-oxo-2-(4-(pyridin-4-yl)pipe...)
Show SMILES CN(CC(=O)N1CCN(CC1)c1ccncc1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C27H28N6O2/c1-30(20-25(34)32-17-15-31(16-18-32)22-11-13-28-14-12-22)27(35)26-29-23-9-5-6-10-24(23)33(26)19-21-7-3-2-4-8-21/h2-14H,15-20H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.18E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264329
PNG
(1-benzyl-N-(1-(4-(1-methylpiperidin-4-yl)piperazin...)
Show SMILES CCC(NC(=O)c1nc2ccccc2n1Cc1ccccc1)C(=O)N1CCN(CC1)C1CCN(C)CC1
Show InChI InChI=1S/C29H38N6O2/c1-3-24(29(37)34-19-17-33(18-20-34)23-13-15-32(2)16-14-23)31-28(36)27-30-25-11-7-8-12-26(25)35(27)21-22-9-5-4-6-10-22/h4-12,23-24H,3,13-21H2,1-2H3,(H,31,36)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264712
PNG
(1-Benzyl-1H-benzoimidazole-2-carboxylic acid [3-(3...)
Show SMILES O=C(CCNC(=O)c1nc2ccccc2n1Cc1ccccc1)N1CCC2(CCOCC2)CC1
Show InChI InChI=1S/C27H32N4O3/c32-24(30-16-11-27(12-17-30)13-18-34-19-14-27)10-15-28-26(33)25-29-22-8-4-5-9-23(22)31(25)20-21-6-2-1-3-7-21/h1-9H,10-20H2,(H,28,33)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.99E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264678
PNG
(CHEMBL491042 | N-(2-((4-(1H-pyrazol-5-yl)benzyl)(m...)
Show SMILES CN(Cc1ccc(cc1)-c1cc[nH]n1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H26N6O2/c1-33(18-21-11-13-22(14-12-21)23-15-16-30-32-23)26(35)17-29-28(36)27-31-24-9-5-6-10-25(24)34(27)19-20-7-3-2-4-8-20/h2-16H,17-19H2,1H3,(H,29,36)(H,30,32)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.13E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264447
PNG
(CHEMBL523266 | [1-(1-Benzyl-1H-benzoimidazole-2-ca...)
Show SMILES O=C(C1CCN(CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C30H32N6O2/c37-29(35-20-18-33(19-21-35)25-10-14-31-15-11-25)24-12-16-34(17-13-24)30(38)28-32-26-8-4-5-9-27(26)36(28)22-23-6-2-1-3-7-23/h1-11,14-15,24H,12-13,16-22H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.31E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264713
PNG
(1-Benzyl-1H-benzoimidazole-2-carboxylic acid [3-(2...)
Show SMILES CN1CCC2(C1)CCN(CC2)C(=O)CCNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C27H33N5O2/c1-30-16-12-27(20-30)13-17-31(18-14-27)24(33)11-15-28-26(34)25-29-22-9-5-6-10-23(22)32(25)19-21-7-3-2-4-8-21/h2-10H,11-20H2,1H3,(H,28,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.91E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264529
PNG
((1-Benzyl-1H-benzoimidazol-2-yl)-{(R)-2-[4-(1-meth...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)[C@H]1CCCN1C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C30H38N6O2/c1-32-16-13-24(14-17-32)33-18-20-34(21-19-33)29(37)27-12-7-15-35(27)30(38)28-31-25-10-5-6-11-26(25)36(28)22-23-8-3-2-4-9-23/h2-6,8-11,24,27H,7,12-22H2,1H3/t27-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.22E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264496
PNG
(CHEMBL487908 | [1-(1-Benzyl-1H-benzoimidazole-2-ca...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)C1CCN(CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C31H40N6O2/c1-33-15-13-26(14-16-33)34-19-21-36(22-20-34)30(38)25-11-17-35(18-12-25)31(39)29-32-27-9-5-6-10-28(27)37(29)23-24-7-3-2-4-8-24/h2-10,25-26H,11-23H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.02E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264498
PNG
((1-Benzyl-1H-benzoimidazol-2-yl)-[(R)-2-(4-pyridin...)
Show SMILES O=C([C@H]1CCCN1C(=O)c1nc2ccccc2n1Cc1ccccc1)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C29H30N6O2/c36-28(33-19-17-32(18-20-33)23-12-14-30-15-13-23)26-11-6-16-34(26)29(37)27-31-24-9-4-5-10-25(24)35(27)21-22-7-2-1-3-8-22/h1-5,7-10,12-15,26H,6,11,16-21H2/t26-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.07E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264299
PNG
(1-benzyl-N-(1-oxo-1-(4-(pyridin-4-yl)piperazin-1-y...)
Show SMILES CCC(NC(=O)c1nc2ccccc2n1Cc1ccccc1)C(=O)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C28H30N6O2/c1-2-23(28(36)33-18-16-32(17-19-33)22-12-14-29-15-13-22)31-27(35)26-30-24-10-6-7-11-25(24)34(26)20-21-8-4-3-5-9-21/h3-15,23H,2,16-20H2,1H3,(H,31,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264267
PNG
((1-benzyl-1H-benzo[d]imidazol-2-yl)(4-(1-methylpip...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C25H31N5O/c1-27-13-11-21(12-14-27)28-15-17-29(18-16-28)25(31)24-26-22-9-5-6-10-23(22)30(24)19-20-7-3-2-4-8-20/h2-10,21H,11-19H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264266
PNG
((1-benzyl-1H-benzo[d]imidazol-2-yl)(4-(pyridin-4-y...)
Show SMILES O=C(N1CCN(CC1)c1ccncc1)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C24H23N5O/c30-24(28-16-14-27(15-17-28)20-10-12-25-13-11-20)23-26-21-8-4-5-9-22(21)29(23)18-19-6-2-1-3-7-19/h1-13H,14-18H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264680
PNG
(1-Benzyl-1H-benzoimidazole-2-carboxylic acid [3-(9...)
Show SMILES CN1CCC2(CC1)CCN(CC2)C(=O)CCNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H35N5O2/c1-31-17-12-28(13-18-31)14-19-32(20-15-28)25(34)11-16-29-27(35)26-30-23-9-5-6-10-24(23)33(26)21-22-7-3-2-4-8-22/h2-10H,11-21H2,1H3,(H,29,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264679
PNG
(CHEMBL491240 | N-(2-((4-(1H-tetrazol-5-yl)benzyl)(...)
Show SMILES CN(Cc1ccc(cc1)-c1nnn[nH]1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C26H24N8O2/c1-33(16-19-11-13-20(14-12-19)24-29-31-32-30-24)23(35)15-27-26(36)25-28-21-9-5-6-10-22(21)34(25)17-18-7-3-2-4-8-18/h2-14H,15-17H2,1H3,(H,27,36)(H,29,30,31,32)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264714
PNG
(1-Benzyl-1H-benzoimidazole-2-carboxylic acid [3-ox...)
Show SMILES O=C(CCNC(=O)c1nc2ccccc2n1Cc1ccccc1)N1CCC2(CNC(=O)O2)CC1
Show InChI InChI=1S/C25H27N5O4/c31-21(29-14-11-25(12-15-29)17-27-24(33)34-25)10-13-26-23(32)22-28-19-8-4-5-9-20(19)30(22)16-18-6-2-1-3-7-18/h1-9H,10-17H2,(H,26,32)(H,27,33)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264559
PNG
(2-[(1-Benzyl-1H-benzoimidazol-2-ylmethyl)-ethyl-am...)
Show SMILES CCN(CC(=O)N1CCN(CC1)c1ccncc1)Cc1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C28H32N6O/c1-2-31(22-28(35)33-18-16-32(17-19-33)24-12-14-29-15-13-24)21-27-30-25-10-6-7-11-26(25)34(27)20-23-8-4-3-5-9-23/h3-15H,2,16-22H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264530
PNG
((1-Benzyl-1H-benzoimidazol-2-yl)-[(S)-2-(4-pyridin...)
Show SMILES O=C([C@@H]1CCCN1C(=O)c1nc2ccccc2n1Cc1ccccc1)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C29H30N6O2/c36-28(33-19-17-32(18-20-33)23-12-14-30-15-13-23)26-11-6-16-34(26)29(37)27-31-24-9-4-5-10-25(24)35(27)21-22-7-2-1-3-8-22/h1-5,7-10,12-15,26H,6,11,16-21H2/t26-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264398
PNG
(1-benzyl-N-isopropyl-N-(2-oxo-2-(4-(pyridin-4-yl)p...)
Show SMILES CC(C)N(CC(=O)N1CCN(CC1)c1ccncc1)C(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C29H32N6O2/c1-22(2)34(21-27(36)33-18-16-32(17-19-33)24-12-14-30-15-13-24)29(37)28-31-25-10-6-7-11-26(25)35(28)20-23-8-4-3-5-9-23/h3-15,22H,16-21H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264588
PNG
(CHEMBL482628 | N-(2-((4-cyanobenzyl)(methyl)amino)...)
Show SMILES CN(Cc1ccc(cc1)C#N)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C26H23N5O2/c1-30(17-21-13-11-19(15-27)12-14-21)24(32)16-28-26(33)25-29-22-9-5-6-10-23(22)31(25)18-20-7-3-2-4-8-20/h2-14H,16-18H2,1H3,(H,28,33)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264562
PNG
(CHEMBL521142 | N-(2-((4-(dimethylcarbamoyl)benzyl)...)
Show SMILES CN(C)C(=O)c1ccc(CN(C)C(=O)CNC(=O)c2nc3ccccc3n2Cc2ccccc2)cc1
Show InChI InChI=1S/C28H29N5O3/c1-31(2)28(36)22-15-13-21(14-16-22)18-32(3)25(34)17-29-27(35)26-30-23-11-7-8-12-24(23)33(26)19-20-9-5-4-6-10-20/h4-16H,17-19H2,1-3H3,(H,29,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264560
PNG
(2-[(1-Benzyl-1H-benzoimidazol-2-ylmethyl)-ethyl-am...)
Show SMILES CCN(CC(=O)N1CCN(CC1)C1CCN(C)CC1)Cc1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C29H40N6O/c1-3-32(23-29(36)34-19-17-33(18-20-34)25-13-15-31(2)16-14-25)22-28-30-26-11-7-8-12-27(26)35(28)21-24-9-5-4-6-10-24/h4-12,25H,3,13-23H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264561
PNG
(CHEMBL483457 | N-(2-((4-carbamoylbenzyl)(methyl)am...)
Show SMILES CN(Cc1ccc(cc1)C(N)=O)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C26H25N5O3/c1-30(16-19-11-13-20(14-12-19)24(27)33)23(32)15-28-26(34)25-29-21-9-5-6-10-22(21)31(25)17-18-7-3-2-4-8-18/h2-14H,15-17H2,1H3,(H2,27,33)(H,28,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair