BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'Beta-lactamase' AND taxid = 654   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-lactamase


(Aeromonas veronii)
BDBM50089390
PNG
(CHEMBL3577963)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2nc3ccccc3s2)[nH]1
Show InChI InChI=1S/C18H13N5O3S2/c24-14(20-17-19-12-7-3-4-8-13(12)28-17)9-27-18-21-15(22-23-18)10-5-1-2-6-11(10)16(25)26/h1-8H,9H2,(H,25,26)(H,19,20,24)(H,21,22,23)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
1.20E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089391
PNG
(CHEMBL3577964)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccc(Cl)cc2)[nH]1
Show InChI InChI=1S/C17H13ClN4O3S/c18-10-5-7-11(8-6-10)19-14(23)9-26-17-20-15(21-22-17)12-3-1-2-4-13(12)16(24)25/h1-8H,9H2,(H,19,23)(H,24,25)(H,20,21,22)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.40E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089388
PNG
(CHEMBL3577961)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccccc2)[nH]1
Show InChI InChI=1S/C17H14N4O3S/c22-14(18-11-6-2-1-3-7-11)10-25-17-19-15(20-21-17)12-8-4-5-9-13(12)16(23)24/h1-9H,10H2,(H,18,22)(H,23,24)(H,19,20,21)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.80E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089393
PNG
(CHEMBL3577970)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2cccc(c2)[N+]([O-])=O)[nH]1
Show InChI InChI=1S/C17H13N5O5S/c23-14(18-10-4-3-5-11(8-10)22(26)27)9-28-17-19-15(20-21-17)12-6-1-2-7-13(12)16(24)25/h1-8H,9H2,(H,18,23)(H,24,25)(H,19,20,21)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.90E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089392
PNG
(CHEMBL3577965)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccc(cc2)[N+]([O-])=O)[nH]1
Show InChI InChI=1S/C17H13N5O5S/c23-14(18-10-5-7-11(8-6-10)22(26)27)9-28-17-19-15(20-21-17)12-3-1-2-4-13(12)16(24)25/h1-8H,9H2,(H,18,23)(H,24,25)(H,19,20,21)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.20E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089385
PNG
(CHEMBL3577967)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccccc2Cl)[nH]1
Show InChI InChI=1S/C17H13ClN4O3S/c18-12-7-3-4-8-13(12)19-14(23)9-26-17-20-15(21-22-17)10-5-1-2-6-11(10)16(24)25/h1-8H,9H2,(H,19,23)(H,24,25)(H,20,21,22)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.30E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089386
PNG
(CHEMBL3577968)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2cccc(Cl)c2)[nH]1
Show InChI InChI=1S/C17H13ClN4O3S/c18-10-4-3-5-11(8-10)19-14(23)9-26-17-20-15(21-22-17)12-6-1-2-7-13(12)16(24)25/h1-8H,9H2,(H,19,23)(H,24,25)(H,20,21,22)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
2.40E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089387
PNG
(CHEMBL3577969)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2ccccc2[N+]([O-])=O)[nH]1
Show InChI InChI=1S/C17H13N5O5S/c23-14(18-12-7-3-4-8-13(12)22(26)27)9-28-17-19-15(20-21-17)10-5-1-2-6-11(10)16(24)25/h1-8H,9H2,(H,18,23)(H,24,25)(H,19,20,21)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
2.70E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089389
PNG
(CHEMBL3577962)
Show SMILES OC(=O)c1ccccc1-c1nnc(SCC(=O)Nc2nc3ccccc3[nH]2)[nH]1
Show InChI InChI=1S/C18H14N6O3S/c25-14(21-17-19-12-7-3-4-8-13(12)20-17)9-28-18-22-15(23-24-18)10-5-1-2-6-11(10)16(26)27/h1-8H,9H2,(H,26,27)(H,22,23,24)(H2,19,20,21,25)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
3.60E+3n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089395
PNG
(CHEMBL3577972)
Show SMILES OC(=O)CCc1nnc(SCC(=O)Nc2nc3ccccc3[nH]2)[nH]1
Show InChI InChI=1S/C14H14N6O3S/c21-11(18-13-15-8-3-1-2-4-9(8)16-13)7-24-14-17-10(19-20-14)5-6-12(22)23/h1-4H,5-7H2,(H,22,23)(H,17,19,20)(H2,15,16,18,21)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
>2.50E+6n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089394
PNG
(CHEMBL3577971)
Show SMILES OC(=O)CCc1nnc(SCC(=O)Nc2ccccc2)[nH]1
Show InChI InChI=1S/C13H14N4O3S/c18-11(14-9-4-2-1-3-5-9)8-21-13-15-10(16-17-13)6-7-12(19)20/h1-5H,6-8H2,(H,14,18)(H,19,20)(H,15,16,17)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
>5.00E+6n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair
Beta-lactamase


(Aeromonas veronii)
BDBM50089396
PNG
(CHEMBL3577974)
Show SMILES OC(=O)CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2)[nH]1
Show InChI InChI=1S/C13H13ClN4O3S/c14-8-1-3-9(4-2-8)15-11(19)7-22-13-16-10(17-18-13)5-6-12(20)21/h1-4H,5-7H2,(H,15,19)(H,20,21)(H,16,17,18)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
>5.00E+6n/an/an/an/an/an/an/an/a



Northwest University

Curated by ChEMBL


Assay Description
Inhibition of Aeromonas veronii metallo-beta-lactamase ImiS expressed in Escherichia coli BL21(DE3) using imipenem substrate pre-incubated for 30 min...


Citation and Details
More data for this
Ligand-Target Pair