BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 44 hits Enz. Inhib. hit(s) with Target = 'Bombesin' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bombesin


(RAT)
BDBM50336889
PNG
((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)
Show SMILES O[C@@](Cc1ncc(CC2(CC2)C(F)(F)F)[nH]1)(c1ccc(cc1)-n1cccn1)C(F)(F)F
Show InChI InChI=1S/C20H18F6N4O/c21-19(22,23)17(6-7-17)10-14-12-27-16(29-14)11-18(31,20(24,25)26)13-2-4-15(5-3-13)30-9-1-8-28-30/h1-5,8-9,12,31H,6-7,10-11H2,(H,27,29)/t18-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
0.600n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]Bag-3 from rat BRS-3


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50336889
PNG
((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)
Show SMILES O[C@@](Cc1ncc(CC2(CC2)C(F)(F)F)[nH]1)(c1ccc(cc1)-n1cccn1)C(F)(F)F
Show InChI InChI=1S/C20H18F6N4O/c21-19(22,23)17(6-7-17)10-14-12-27-16(29-14)11-18(31,20(24,25)26)13-2-4-15(5-3-13)30-9-1-8-28-30/h1-5,8-9,12,31H,6-7,10-11H2,(H,27,29)/t18-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
0.600n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]Bag-3 from rat BRS-3


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50010685
PNG
((+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahyd...)
Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O
Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of North Carolina

Curated by PDSP Ki Database




J Pharmacol Exp Ther 262: 383-93 (1992)

More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50094703
PNG
(5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...)
Show SMILES Nc1ncnc2nc(cc(-c3cccc(Br)c3)c12)-c1ccc(nc1)N1CCOCC1
Show InChI InChI=1S/C22H19BrN6O/c23-16-3-1-2-14(10-16)17-11-18(28-22-20(17)21(24)26-13-27-22)15-4-5-19(25-12-15)29-6-8-30-9-7-29/h1-5,10-13H,6-9H2,(H2,24,26,27,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by PDSP Ki Database




J Pharmacol Exp Ther 295: 1156-64 (2000)

More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM29525
PNG
(3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...)
Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12
Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Br J Pharmacol 111: 332-8 (1994)

More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50314969
PNG
(2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)
Show SMILES CCC(C)(C)Cc1cnc(CCc2ccc(cc2)-c2ccccn2)[nH]1
Show InChI InChI=1S/C22H27N3/c1-4-22(2,3)15-19-16-24-21(25-19)13-10-17-8-11-18(12-9-17)20-7-5-6-14-23-20/h5-9,11-12,14,16H,4,10,13,15H2,1-3H3,(H,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 2.40n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]D-Tyr6-betaAla11-Phe13-Nle14-bombesin from rat BRS-3 expressed in NFAT-CHO cells after 2 hrs by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317451
PNG
(CHEMBL1098838 | N-(7-benzyl-5-(piperidin-1-yl)-6,7...)
Show SMILES O=C(Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12)C1CCCC1
Show InChI InChI=1S/C27H34N6O/c34-27(20-11-5-6-12-20)29-25-23-21-13-16-32(17-19-9-3-1-4-10-19)18-22(21)26(28-24(23)30-31-25)33-14-7-2-8-15-33/h1,3-4,9-10,20H,2,5-8,11-18H2,(H2,28,29,30,31,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 413n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317452
PNG
(CHEMBL1098837 | N-(7-Benzyl-5-(piperidin-1-yl)-6,7...)
Show SMILES CC(C)(C)CC(=O)Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C27H36N6O/c1-27(2,3)16-22(34)28-24-23-20-12-15-32(17-19-10-6-4-7-11-19)18-21(20)26(29-25(23)31-30-24)33-13-8-5-9-14-33/h4,6-7,10-11H,5,8-9,12-18H2,1-3H3,(H2,28,29,30,31,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 433n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317453
PNG
(CHEMBL1098836 | N-(7-benzyl-5-(piperidin-1-yl)-6,7...)
Show SMILES CC(C)(C)C(=O)Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C26H34N6O/c1-26(2,3)25(33)28-23-21-19-12-15-31(16-18-10-6-4-7-11-18)17-20(19)24(27-22(21)29-30-23)32-13-8-5-9-14-32/h4,6-7,10-11H,5,8-9,12-17H2,1-3H3,(H2,27,28,29,30,33)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 63n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317454
PNG
(CHEMBL1096193 | N-(7-benzyl-5-(piperidin-1-yl)-6,7...)
Show SMILES CC(C)C(=O)Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C25H32N6O/c1-17(2)25(32)27-23-21-19-11-14-30(15-18-9-5-3-6-10-18)16-20(19)24(26-22(21)28-29-23)31-12-7-4-8-13-31/h3,5-6,9-10,17H,4,7-8,11-16H2,1-2H3,(H2,26,27,28,29,32)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 99n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317456
PNG
(CHEMBL1099122 | N-(7-benzyl-5-(piperidin-1-yl)-6,7...)
Show SMILES CC(=O)Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C23H28N6O/c1-16(30)24-21-20-18-10-13-28(14-17-8-4-2-5-9-17)15-19(18)23(25-22(20)27-26-21)29-11-6-3-7-12-29/h2,4-5,8-9H,3,6-7,10-15H2,1H3,(H2,24,25,26,27,30)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 129n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317457
PNG
(7-(4-Fluorobenzoyl)-5-(piperidin-1-yl)-6,7,8,9-tet...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(CCc3c12)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C21H23FN6O/c22-14-6-4-13(5-7-14)21(29)28-11-8-15-16(12-28)20(27-9-2-1-3-10-27)24-19-17(15)18(23)25-26-19/h4-7H,1-3,8-12H2,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317458
PNG
(7-phenethyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(CCc4ccccc4)CCc3c12
Show InChI InChI=1S/C22H28N6/c23-20-19-17-10-14-27(13-9-16-7-3-1-4-8-16)15-18(17)22(24-21(19)26-25-20)28-11-5-2-6-12-28/h1,3-4,7-8H,2,5-6,9-15H2,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 7.91E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317459
PNG
(7-neopentyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-...)
Show SMILES CC(C)(C)CN1CCc2c(C1)c(nc1[nH]nc(N)c21)N1CCCCC1
Show InChI InChI=1S/C19H30N6/c1-19(2,3)12-24-10-7-13-14(11-24)18(25-8-5-4-6-9-25)21-17-15(13)16(20)22-23-17/h4-12H2,1-3H3,(H3,20,21,22,23)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.06E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317460
PNG
(7-isobutyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3...)
Show SMILES CC(C)CN1CCc2c(C1)c(nc1[nH]nc(N)c21)N1CCCCC1
Show InChI InChI=1S/C18H28N6/c1-12(2)10-23-9-6-13-14(11-23)18(24-7-4-3-5-8-24)20-17-15(13)16(19)21-22-17/h12H,3-11H2,1-2H3,(H3,19,20,21,22)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317461
PNG
(7-(cyclohexylmethyl)-5-(piperidin-1-yl)-6,7,8,9-te...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(CC4CCCCC4)CCc3c12
Show InChI InChI=1S/C21H32N6/c22-19-18-16-9-12-26(13-15-7-3-1-4-8-15)14-17(16)21(23-20(18)25-24-19)27-10-5-2-6-11-27/h15H,1-14H2,(H3,22,23,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317462
PNG
(7-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(piperidin-1-...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccc5OCOc5c4)CCc3c12
Show InChI InChI=1S/C22H26N6O2/c23-20-19-15-6-9-27(11-14-4-5-17-18(10-14)30-13-29-17)12-16(15)22(24-21(19)26-25-20)28-7-2-1-3-8-28/h4-5,10H,1-3,6-9,11-13H2,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 402n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317463
PNG
(5-(piperidin-1-yl)-7-(3-(trifluoromethyl)benzyl)-6...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4cccc(c4)C(F)(F)F)CCc3c12
Show InChI InChI=1S/C22H25F3N6/c23-22(24,25)15-6-4-5-14(11-15)12-30-10-7-16-17(13-30)21(31-8-2-1-3-9-31)27-20-18(16)19(26)28-29-20/h4-6,11H,1-3,7-10,12-13H2,(H3,26,27,28,29)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317464
PNG
(7-(4-methoxybenzyl)-5-(piperidin-1-yl)-6,7,8,9-tet...)
Show SMILES COc1ccc(CN2CCc3c(C2)c(nc2[nH]nc(N)c32)N2CCCCC2)cc1
Show InChI InChI=1S/C22H28N6O/c1-29-16-7-5-15(6-8-16)13-27-12-9-17-18(14-27)22(28-10-3-2-4-11-28)24-21-19(17)20(23)25-26-21/h5-8H,2-4,9-14H2,1H3,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317466
PNG
(7-(2-chlorobenzyl)-5-(piperidin-1-yl)-6,7,8,9-tetr...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4Cl)CCc3c12
Show InChI InChI=1S/C21H25ClN6/c22-17-7-3-2-6-14(17)12-27-11-8-15-16(13-27)21(28-9-4-1-5-10-28)24-20-18(15)19(23)25-26-20/h2-3,6-7H,1,4-5,8-13H2,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 342n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317467
PNG
(5-(Piperidin-1-yl)-7-(pyridin-2-ylmethyl)-6,7,8,9-...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccn4)CCc3c12
Show InChI InChI=1S/C20H25N7/c21-18-17-15-7-11-26(12-14-6-2-3-8-22-14)13-16(15)20(23-19(17)25-24-18)27-9-4-1-5-10-27/h2-3,6,8H,1,4-5,7,9-13H2,(H3,21,23,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 346n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50378777
PNG
(CHEMBL1204083)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CNCCc3c12
Show InChI InChI=1S/C14H20N6/c15-12-11-9-4-5-16-8-10(9)14(17-13(11)19-18-12)20-6-2-1-3-7-20/h16H,1-8H2,(H3,15,17,18,19)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317469
PNG
(7-benzyl-N5-phenyl-6,7,8,9-tetrahydro-3H-pyrazolo[...)
Show SMILES Nc1n[nH]c2nc(Nc3ccccc3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C22H22N6/c23-20-19-17-11-12-28(13-15-7-3-1-4-8-15)14-18(17)21(25-22(19)27-26-20)24-16-9-5-2-6-10-16/h1-10H,11-14H2,(H4,23,24,25,26,27)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317470
PNG
(7-benzyl-N5-cyclohexyl-6,7,8,9-tetrahydro-3H-pyraz...)
Show SMILES Nc1n[nH]c2nc(NC3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C22H28N6/c23-20-19-17-11-12-28(13-15-7-3-1-4-8-15)14-18(17)21(25-22(19)27-26-20)24-16-9-5-2-6-10-16/h1,3-4,7-8,16H,2,5-6,9-14H2,(H4,23,24,25,26,27)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317455
PNG
(CHEMBL1099123 | N-(7-benzyl-5-(piperidin-1-yl)-6,7...)
Show SMILES CCC(=O)Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C24H30N6O/c1-2-20(31)25-22-21-18-11-14-29(15-17-9-5-3-6-10-17)16-19(18)24(26-23(21)28-27-22)30-12-7-4-8-13-30/h3,5-6,9-10H,2,4,7-8,11-16H2,1H3,(H2,25,26,27,28,31)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 123n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317472
PNG
(7-benzyl-N5,N5-dimethyl-6,7,8,9-tetrahydro-3H-pyra...)
Show SMILES CN(C)c1nc2[nH]nc(N)c2c2CCN(Cc3ccccc3)Cc12
Show InChI InChI=1S/C18H22N6/c1-23(2)18-14-11-24(10-12-6-4-3-5-7-12)9-8-13(14)15-16(19)21-22-17(15)20-18/h3-7H,8-11H2,1-2H3,(H3,19,20,21,22)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 8.95E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317473
PNG
(7-benzyl-5-(4-methylpiperazin-1-yl)-6,7,8,9-tetrah...)
Show SMILES CN1CCN(CC1)c1nc2[nH]nc(N)c2c2CCN(Cc3ccccc3)Cc12
Show InChI InChI=1S/C21H27N7/c1-26-9-11-28(12-10-26)21-17-14-27(13-15-5-3-2-4-6-15)8-7-16(17)18-19(22)24-25-20(18)23-21/h2-6H,7-14H2,1H3,(H3,22,23,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317474
PNG
(7-benzyl-5-(piperazin-1-yl)-6,7,8,9-tetrahydro-3H-...)
Show SMILES Nc1n[nH]c2nc(N3CCNCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C20H25N7/c21-18-17-15-6-9-26(12-14-4-2-1-3-5-14)13-16(15)20(23-19(17)25-24-18)27-10-7-22-8-11-27/h1-5,22H,6-13H2,(H3,21,23,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317475
PNG
(7-benzyl-5-morpholino-6,7,8,9-tetrahydro-3H-pyrazo...)
Show SMILES Nc1n[nH]c2nc(N3CCOCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C20H24N6O/c21-18-17-15-6-7-25(12-14-4-2-1-3-5-14)13-16(15)20(22-19(17)24-23-18)26-8-10-27-11-9-26/h1-5H,6-13H2,(H3,21,22,23,24)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 3.56E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317476
PNG
(7-benzyl-5-(4-fluoropiperidin-1-yl)-6,7,8,9-tetrah...)
Show SMILES Nc1n[nH]c2nc(N3CCC(F)CC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C21H25FN6/c22-15-6-10-28(11-7-15)21-17-13-27(12-14-4-2-1-3-5-14)9-8-16(17)18-19(23)25-26-20(18)24-21/h1-5,15H,6-13H2,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 481n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317477
PNG
(7-benzyl-5-(4-methylpiperidin-1-yl)-6,7,8,9-tetrah...)
Show SMILES CC1CCN(CC1)c1nc2[nH]nc(N)c2c2CCN(Cc3ccccc3)Cc12
Show InChI InChI=1S/C22H28N6/c1-15-7-11-28(12-8-15)22-18-14-27(13-16-5-3-2-4-6-16)10-9-17(18)19-20(23)25-26-21(19)24-22/h2-6,15H,7-14H2,1H3,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 854n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317478
PNG
(5-(azocan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyr...)
Show SMILES Nc1n[nH]c2nc(N3CCCCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C23H30N6/c24-21-20-18-11-14-28(15-17-9-5-4-6-10-17)16-19(18)23(25-22(20)27-26-21)29-12-7-2-1-3-8-13-29/h4-6,9-10H,1-3,7-8,11-16H2,(H3,24,25,26,27)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317471
PNG
(7-benzyl-N5-isopropyl-6,7,8,9-tetrahydro-3H-pyrazo...)
Show SMILES CC(C)Nc1nc2[nH]nc(N)c2c2CCN(Cc3ccccc3)Cc12
Show InChI InChI=1S/C19H24N6/c1-12(2)21-18-15-11-25(10-13-6-4-3-5-7-13)9-8-14(15)16-17(20)23-24-19(16)22-18/h3-7,12H,8-11H2,1-2H3,(H4,20,21,22,23,24)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 7.65E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317448
PNG
(7-Benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-...)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C21H26N6/c22-19-18-16-9-12-26(13-15-7-3-1-4-8-15)14-17(16)21(23-20(18)25-24-19)27-10-5-2-6-11-27/h1,3-4,7-8H,2,5-6,9-14H2,(H3,22,23,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 380n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317449
PNG
(7-benzyl-5-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-3H...)
Show SMILES Nc1n[nH]c2nc(N3CCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C20H24N6/c21-18-17-15-8-11-25(12-14-6-2-1-3-7-14)13-16(15)20(22-19(17)24-23-18)26-9-4-5-10-26/h1-3,6-7H,4-5,8-13H2,(H3,21,22,23,24)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 965n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317450
PNG
(5-(azepan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyr...)
Show SMILES Nc1n[nH]c2nc(N3CCCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C22H28N6/c23-20-19-17-10-13-27(14-16-8-4-3-5-9-16)15-18(17)22(24-21(19)26-25-20)28-11-6-1-2-7-12-28/h3-5,8-9H,1-2,6-7,10-15H2,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.44E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50415868
PNG
(CHEMBL1199153)
Show SMILES Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccc(F)cc4)CCc3c12
Show InChI InChI=1S/C21H25FN6/c22-15-6-4-14(5-7-15)12-27-11-8-16-17(13-27)21(28-9-2-1-3-10-28)24-20-18(16)19(23)25-26-20/h4-7H,1-3,8-13H2,(H3,23,24,25,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 3.86E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317447
PNG
(CHEMBL1099135 | N-(7-benzyl-5-(piperidin-1-yl)-6,7...)
Show SMILES CCC(C)(C)C(=O)Nc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C27H36N6O/c1-4-27(2,3)26(34)29-24-22-20-13-16-32(17-19-11-7-5-8-12-19)18-21(20)25(28-23(22)30-31-24)33-14-9-6-10-15-33/h5,7-8,11-12H,4,6,9-10,13-18H2,1-3H3,(H2,28,29,30,31,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 212n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317446
PNG
(7-benzyl-N-ethyl-5-(piperidin-1-yl)-6,7,8,9-tetrah...)
Show SMILES CCNc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C23H30N6/c1-2-24-21-20-18-11-14-28(15-17-9-5-3-6-10-17)16-19(18)23(25-22(20)27-26-21)29-12-7-4-8-13-29/h3,5-6,9-10H,2,4,7-8,11-16H2,1H3,(H2,24,25,26,27)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 471n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317445
PNG
(7-benzyl-N-neopentyl-5-(piperidin-1-yl)-6,7,8,9-te...)
Show SMILES CC(C)(C)CNc1n[nH]c2nc(N3CCCCC3)c3CN(Cc4ccccc4)CCc3c12
Show InChI InChI=1S/C26H36N6/c1-26(2,3)18-27-23-22-20-12-15-31(16-19-10-6-4-7-11-19)17-21(20)25(28-24(22)30-29-23)32-13-8-5-9-14-32/h4,6-7,10-11H,5,8-9,12-18H2,1-3H3,(H2,27,28,29,30)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 680n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317444
PNG
(7-benzyl-3-methyl-5-(piperidin-1-yl)-6,7,8,9-tetra...)
Show SMILES Cn1nc(N)c2c3CCN(Cc4ccccc4)Cc3c(nc12)N1CCCCC1
Show InChI InChI=1S/C22H28N6/c1-26-22-19(20(23)25-26)17-10-13-27(14-16-8-4-2-5-9-16)15-18(17)21(24-22)28-11-6-3-7-12-28/h2,4-5,8-9H,3,6-7,10-15H2,1H3,(H2,23,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 6.06E+3n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50317443
PNG
(1-(1-amino-7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tet...)
Show SMILES CC(=O)n1nc(N)c2c3CCN(Cc4ccccc4)Cc3c(nc12)N1CCCCC1
Show InChI InChI=1S/C23H28N6O/c1-16(30)29-23-20(21(24)26-29)18-10-13-27(14-17-8-4-2-5-9-17)15-19(18)22(25-23)28-11-6-3-7-12-28/h2,4-5,8-9H,3,6-7,10-15H2,1H3,(H2,24,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 759n/an/an/an/a



AMRI

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS3 expressed in HEK293AEQ cells after 10 mins by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50336889
PNG
((2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]...)
Show SMILES O[C@@](Cc1ncc(CC2(CC2)C(F)(F)F)[nH]1)(c1ccc(cc1)-n1cccn1)C(F)(F)F
Show InChI InChI=1S/C20H18F6N4O/c21-19(22,23)17(6-7-17)10-14-12-27-16(29-14)11-18(31,20(24,25)26)13-2-4-15(5-3-13)30-9-1-8-28-30/h1-5,8-9,12,31H,6-7,10-11H2,(H,27,29)/t18-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/an/an/a 2.20n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at rat BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence as...


Citation and Details
More data for this
Ligand-Target Pair
Bombesin


(RAT)
BDBM50313710
PNG
(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Show SMILES CCCCc1cnc([nH]1)C(CCCO)Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C25H30N2O3/c1-2-3-8-21-17-26-24(27-21)20(7-6-15-28)16-18-11-13-19(14-12-18)22-9-4-5-10-23(22)25(29)30/h4-5,9-14,17,20,28H,2-3,6-8,15-16H2,1H3,(H,26,27)(H,29,30)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 174n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity at rat BRS3 expressed in HEK293AEO at 10 uM by aequorin bioluminescence assay


Citation and Details
More data for this
Ligand-Target Pair