BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 12 hits Enz. Inhib. hit(s) with Target = 'Bone morphogenetic protein 4' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434750
PNG
(CHEMBL2385596)
Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12
Show InChI InChI=1S/C26H24N6/c1-30-12-14-31(15-13-30)21-8-6-19(7-9-21)20-16-28-26-24(17-29-32(26)18-20)22-10-11-27-25-5-3-2-4-23(22)25/h2-11,16-18H,12-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434748
PNG
(CHEMBL2385600)
Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cn[nH]c1
Show InChI InChI=1S/C16H13N5O/c1-22-14-4-2-11(3-5-14)13-6-17-16-15(9-20-21(16)10-13)12-7-18-19-8-12/h2-10H,1H3,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 94n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM102618
PNG
(LDN-212854)
Show SMILES C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12
Show InChI InChI=1S/C25H22N6/c1-3-21(22-4-2-10-27-24(22)5-1)23-16-29-31-17-19(15-28-25(23)31)18-6-8-20(9-7-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 117n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434751
PNG
(CHEMBL2385579)
Show SMILES C1CN(CCO1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1cn[nH]c1
Show InChI InChI=1S/C19H18N6O/c1-3-17(24-5-7-26-8-6-24)4-2-14(1)16-9-20-19-18(12-23-25(19)13-16)15-10-21-22-11-15/h1-4,9-13H,5-8H2,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 141n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50261979
PNG
(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12
Show InChI InChI=1S/C22H16N4O/c1-27-17-9-7-15(8-10-17)16-12-24-22-20(13-25-26(22)14-16)18-4-2-6-21-19(18)5-3-11-23-21/h2-14H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 152n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434759
PNG
(CHEMBL2385588)
Show SMILES Clc1cc(ccn1)-c1cnn2cc(cnc12)-c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C21H19ClN6/c22-20-11-16(5-6-24-20)19-13-26-28-14-17(12-25-21(19)28)15-1-3-18(4-2-15)27-9-7-23-8-10-27/h1-6,11-14,23H,7-10H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 246n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434758
PNG
(CHEMBL2385585)
Show SMILES C1CN(CCO1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc2ccccc12
Show InChI InChI=1S/C24H20N4OS/c1-2-4-23-20(3-1)22(16-30-23)21-14-26-28-15-18(13-25-24(21)28)17-5-7-19(8-6-17)27-9-11-29-12-10-27/h1-8,13-16H,9-12H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 418n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434757
PNG
(CHEMBL2385595)
Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc(Cl)c1
Show InChI InChI=1S/C22H21ClN6/c1-27-8-10-28(11-9-27)19-4-2-16(3-5-19)18-13-25-22-20(14-26-29(22)15-18)17-6-7-24-21(23)12-17/h2-7,12-15H,8-11H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 523n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434756
PNG
(CHEMBL2385581)
Show SMILES Clc1cc(ccn1)-c1cnn2cc(cnc12)-c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C21H18ClN5O/c22-20-11-16(5-6-23-20)19-13-25-27-14-17(12-24-21(19)27)15-1-3-18(4-2-15)26-7-9-28-10-8-26/h1-6,11-14H,7-10H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 529n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434755
PNG
(CHEMBL2385592)
Show SMILES C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc2ccccc12
Show InChI InChI=1S/C24H21N5S/c1-2-4-23-20(3-1)22(16-30-23)21-14-27-29-15-18(13-26-24(21)29)17-5-7-19(8-6-17)28-11-9-25-10-12-28/h1-8,13-16,25H,9-12H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.64E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434754
PNG
(CHEMBL2385578)
Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccsc12
Show InChI InChI=1S/C20H14N4OS/c1-25-15-4-2-13(3-5-15)14-10-22-20-17(11-23-24(20)12-14)16-6-8-21-18-7-9-26-19(16)18/h2-12H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 4.57E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair
Bone morphogenetic protein 4


(Mus musculus)
BDBM50434753
PNG
(CHEMBL2385403)
Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cncc2ccccc12
Show InChI InChI=1S/C22H16N4O/c1-27-18-8-6-15(7-9-18)17-11-24-22-21(13-25-26(22)14-17)20-12-23-10-16-4-2-3-5-19(16)20/h2-14H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6.73E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay


Citation and Details
More data for this
Ligand-Target Pair