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Found 11 hits Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 6' AND taxid = 9913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 6


(Bos taurus)
BDBM50212308
PNG
(CHEMBL130950)
Show SMILES NS(=O)(=O)c1nnc(NC(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)s1
Show InChI InChI=1S/C19H19N5O5S2/c20-31(27,28)19-24-23-17(30-19)22-16(25)15(11-13-7-3-1-4-8-13)21-18(26)29-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H,21,26)(H2,20,27,28)(H,22,23,25)/t15-/m0/s1
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n/an/a 5n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212306
PNG
(CHEMBL129880)
Show SMILES C[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C13H15N5O5S2/c1-8(15-12(20)23-7-9-5-3-2-4-6-9)10(19)16-11-17-18-13(24-11)25(14,21)22/h2-6,8H,7H2,1H3,(H,15,20)(H2,14,21,22)(H,16,17,19)/t8-/m0/s1
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n/an/a 7n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212310
PNG
(CHEMBL335243)
Show SMILES NS(=O)(=O)c1nnc(NC(=O)CNC(=O)OCc2ccccc2)s1
Show InChI InChI=1S/C12H13N5O5S2/c13-24(20,21)12-17-16-10(23-12)15-9(18)6-14-11(19)22-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,14,19)(H2,13,20,21)(H,15,16,18)
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n/an/a 8n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212307
PNG
(CHEMBL336554)
Show SMILES Br.C[C@H](N)C(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C5H9N5O3S2.BrH/c1-2(6)3(11)8-4-9-10-5(14-4)15(7,12)13;/h2H,6H2,1H3,(H2,7,12,13)(H,8,9,11);1H/t2-;/m0./s1
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n/an/a 9n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50080659
PNG
(2-Amino-N-(5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-ace...)
Show SMILES NCC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H7N5O3S2/c5-1-2(10)7-3-8-9-4(13-3)14(6,11)12/h1,5H2,(H2,6,11,12)(H,7,8,10)
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n/an/a 10n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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Similars

n/an/a 16n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212316
PNG
(CHEMBL133619)
Show SMILES Br.N[C@@H](Cc1ccccc1)C(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C11H13N5O3S2.BrH/c12-8(6-7-4-2-1-3-5-7)9(17)14-10-15-16-11(20-10)21(13,18)19;/h1-5,8H,6,12H2,(H2,13,18,19)(H,14,15,17);1H/t8-;/m0./s1
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n/an/a 30n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212309
PNG
(CHEMBL91302)
Show SMILES NCCCCC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C7H13N5O3S2/c8-4-2-1-3-5(13)10-6-11-12-7(16-6)17(9,14)15/h1-4,8H2,(H2,9,14,15)(H,10,11,13)
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n/an/a 370n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212309
PNG
(CHEMBL91302)
Show SMILES NCCCCC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C7H13N5O3S2/c8-4-2-1-3-5(13)10-6-11-12-7(16-6)17(9,14)15/h1-4,8H2,(H2,9,14,15)(H,10,11,13)
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n/an/a 440n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212305
PNG
(CHEMBL129895)
Show SMILES CC(C)COC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C7H12N4O4S2/c1-4(2)3-15-6(12)9-5-10-11-7(16-5)17(8,13)14/h4H,3H2,1-2H3,(H2,8,13,14)(H,9,10,12)
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n/an/a 550n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6


(Bos taurus)
BDBM50212305
PNG
(CHEMBL129895)
Show SMILES CC(C)COC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C7H12N4O4S2/c1-4(2)3-15-6(12)9-5-10-11-7(16-5)17(8,13)14/h4H,3H2,1-2H3,(H2,8,13,14)(H,9,10,12)
UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem

Similars

n/an/a 570n/an/an/an/an/an/a


TBA

Assay Description
In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte


Citation and Details
More data for this
Ligand-Target Pair