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Found 34 hits Enz. Inhib. hit(s) with Target = 'Carboxypeptidase B' AND taxid = 7113   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81910
PNG
(1-((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl...)
Show SMILES CC(NC(=S)N(Cc1cccs1)Cc1cc2cc(C)ccc2[nH]c1=O)c1ccccc1
Show InChI InChI=1S/C25H25N3OS2/c1-17-10-11-23-20(13-17)14-21(24(29)27-23)15-28(16-22-9-6-12-31-22)25(30)26-18(2)19-7-4-3-5-8-19/h3-14,18H,15-16H2,1-2H3,(H,26,30)(H,27,29)
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580n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296411
PNG
(1-(4-chlorophenyl)-2-(5-(2-hydroxyphenyl)-1,3,4-ox...)
Show SMILES Oc1ccccc1-c1nnc(SCC(=O)c2ccc(Cl)cc2)o1
Show InChI InChI=1S/C16H11ClN2O3S/c17-11-7-5-10(6-8-11)14(21)9-23-16-19-18-15(22-16)12-3-1-2-4-13(12)20/h1-8,20H,9H2
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1.00E+3n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81911
PNG
(methyl 2-(3-furan-2-ylmethyl)-3-((8-methyl-2-oxo-1...)
Show SMILES COC(=O)c1ccccc1NC(=S)N(Cc1ccco1)Cc1cc2cccc(C)c2[nH]c1=O
Show InChI InChI=1S/C25H23N3O4S/c1-16-7-5-8-17-13-18(23(29)27-22(16)17)14-28(15-19-9-6-12-32-19)25(33)26-21-11-4-3-10-20(21)24(30)31-2/h3-13H,14-15H2,1-2H3,(H,26,33)(H,27,29)
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1.20E+3n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296413
PNG
(CHEMBL551268 | N-benzyl-N-(4-phenylthiazol-2-yl)cy...)
Show SMILES O=C(C1CC1)N(Cc1ccccc1)c1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C20H18N2OS/c23-19(17-11-12-17)22(13-15-7-3-1-4-8-15)20-21-18(14-24-20)16-9-5-2-6-10-16/h1-10,14,17H,11-13H2
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1.20E+3n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296415
PNG
(4-(5-(2-chlorobenzylthio)-1,3,4-oxadiazol-2-yl)-N-...)
Show SMILES Clc1ccccc1CSc1nnc(o1)-c1ccc(cc1)S(=O)(=O)NCc1cccs1
Show InChI InChI=1S/C20H16ClN3O3S3/c21-18-6-2-1-4-15(18)13-29-20-24-23-19(27-20)14-7-9-17(10-8-14)30(25,26)22-12-16-5-3-11-28-16/h1-11,22H,12-13H2
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1.40E+3n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81906
PNG
(2-(5-(naphthalen-2-yloxy)methyl)-1,3,4-oxadiazol-2...)
Show SMILES Cc1ccc(cc1)C(=O)CSc1nnc(COc2ccc3ccccc3c2)o1
Show InChI InChI=1S/C22H18N2O3S/c1-15-6-8-17(9-7-15)20(25)14-28-22-24-23-21(27-22)13-26-19-11-10-16-4-2-3-5-18(16)12-19/h2-12H,13-14H2,1H3
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1.60E+3n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296414
PNG
(CHEMBL552336 | N-(3-chlorophenyl)-4-((5-(3-methoxy...)
Show SMILES COc1cccc(CSc2nnc(Cc3csc(Nc4cccc(Cl)c4)n3)o2)c1
Show InChI InChI=1S/C20H17ClN4O2S2/c1-26-17-7-2-4-13(8-17)11-29-20-25-24-18(27-20)10-16-12-28-19(23-16)22-15-6-3-5-14(21)9-15/h2-9,12H,10-11H2,1H3,(H,22,23)
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3.60E+3n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81905
PNG
(1-(3,4-dihydroisoquinolin-1(1H)-yl)-2-(5-(3,5-dime...)
Show SMILES Cc1cc(C)cc(c1)-c1nnc(SCC(=O)N2CCCc3ccccc23)o1
Show InChI InChI=1S/C21H21N3O2S/c1-14-10-15(2)12-17(11-14)20-22-23-21(26-20)27-13-19(25)24-9-5-7-16-6-3-4-8-18(16)24/h3-4,6,8,10-12H,5,7,9,13H2,1-2H3
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4.10E+3n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296418
PNG
(2-(6,9-dimethyl-5H-[1,2,4]triazino[5,6-b]indol-3-y...)
Show SMILES Cc1ccc(C)c2c3nnc(SCC(=O)c4ccc(F)cc4)nc3[nH]c12
Show InChI InChI=1S/C19H15FN4OS/c1-10-3-4-11(2)16-15(10)17-18(21-16)22-19(24-23-17)26-9-14(25)12-5-7-13(20)8-6-12/h3-8H,9H2,1-2H3,(H,21,22,24)
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9.00E+3n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296420
PNG
(CHEMBL558714 | ethyl 2-(4-ethyl-5-((4-ethylphenoxy...)
Show SMILES CCOC(=O)C(Sc1nnc(COc2ccc(CC)cc2)n1CC)C(C)C
Show InChI InChI=1S/C20H29N3O3S/c1-6-15-9-11-16(12-10-15)26-13-17-21-22-20(23(17)7-2)27-18(14(4)5)19(24)25-8-3/h9-12,14,18H,6-8,13H2,1-5H3
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1.19E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50121929
PNG
((phenylmethyl)butanedioic acid | 2-benzylbutanedio...)
Show SMILES OC(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C11H12O4/c12-10(13)7-9(11(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,13)(H,14,15)
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1.19E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296422
PNG
(2-(5-((4-chlorophenoxy)methyl)-1,3,4-oxadiazol-2-y...)
Show SMILES Cc1ccc(cc1)C(=O)CSc1nnc(COc2ccc(Cl)cc2)o1
Show InChI InChI=1S/C18H15ClN2O3S/c1-12-2-4-13(5-3-12)16(22)11-25-18-21-20-17(24-18)10-23-15-8-6-14(19)7-9-15/h2-9H,10-11H2,1H3
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1.20E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296423
PNG
(CHEMBL551672 | N-(2-chlorobenzyl)-N-(furan-2-ylmet...)
Show SMILES Cc1cc(ccc1-n1cnnn1)S(=O)(=O)N(Cc1ccco1)Cc1ccccc1Cl
Show InChI InChI=1S/C20H18ClN5O3S/c1-15-11-18(8-9-20(15)26-14-22-23-24-26)30(27,28)25(13-17-6-4-10-29-17)12-16-5-2-3-7-19(16)21/h2-11,14H,12-13H2,1H3
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1.26E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM47512
PNG
(1-(4-methylphenyl)-2-[[5-(8-quinolinyloxymethyl)-1...)
Show SMILES Cc1ccc(cc1)C(=O)CSc1nnc(COc2cccc3cccnc23)o1
Show InChI InChI=1S/C21H17N3O3S/c1-14-7-9-15(10-8-14)17(25)13-28-21-24-23-19(27-21)12-26-18-6-2-4-16-5-3-11-22-20(16)18/h2-11H,12-13H2,1H3
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1.40E+4n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296425
PNG
(2-(pyridin-4-ylmethylamino)-1-(4-tosylpiperazin-1-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNCc1ccncc1
Show InChI InChI=1S/C19H24N4O3S/c1-16-2-4-18(5-3-16)27(25,26)23-12-10-22(11-13-23)19(24)15-21-14-17-6-8-20-9-7-17/h2-9,21H,10-15H2,1H3
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1.80E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296427
PNG
(2-(4-benzoylpiperidine-1-carbonyl)benzoic acid | C...)
Show SMILES OC(=O)c1ccccc1C(=O)N1CCC(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C20H19NO4/c22-18(14-6-2-1-3-7-14)15-10-12-21(13-11-15)19(23)16-8-4-5-9-17(16)20(24)25/h1-9,15H,10-13H2,(H,24,25)
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1.96E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296428
PNG
(2-(2-methoxyphenyl)-N-(5-(4-methoxyphenyl)-1,3,4-t...)
Show SMILES CCCN(C(=O)Cc1ccccc1OC)c1nnc(s1)-c1ccc(OC)cc1
Show InChI InChI=1S/C21H23N3O3S/c1-4-13-24(19(25)14-16-7-5-6-8-18(16)27-3)21-23-22-20(28-21)15-9-11-17(26-2)12-10-15/h5-12H,4,13-14H2,1-3H3
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1.97E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81907
PNG
(1-(2-hydroxyethyl)-1-((6-methoxy-2-oxo-1,2-dihydro...)
Show SMILES COc1ccc2[nH]c(=O)c(CN(CCO)C(=S)Nc3ccc(C)cc3)cc2c1
Show InChI InChI=1S/C21H23N3O3S/c1-14-3-5-17(6-4-14)22-21(28)24(9-10-25)13-16-11-15-12-18(27-2)7-8-19(15)23-20(16)26/h3-8,11-12,25H,9-10,13H2,1-2H3,(H,22,28)(H,23,26)
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2.05E+4n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296421
PNG
(2-(4-benzyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-y...)
Show SMILES NC(=O)CSc1nnc(-c2cccs2)n1Cc1ccccc1
Show InChI InChI=1S/C15H14N4OS2/c16-13(20)10-22-15-18-17-14(12-7-4-8-21-12)19(15)9-11-5-2-1-3-6-11/h1-8H,9-10H2,(H2,16,20)
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2.72E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296430
PNG
(CHEMBL563306 | N-(3-methoxybenzyl)-3-methyl-N-(pyr...)
Show SMILES COc1cccc(CN(Cc2cccnc2)S(=O)(=O)c2ccc(c(C)c2)-n2cnnn2)c1
Show InChI InChI=1S/C22H22N6O3S/c1-17-11-21(8-9-22(17)28-16-24-25-26-28)32(29,30)27(15-19-6-4-10-23-13-19)14-18-5-3-7-20(12-18)31-2/h3-13,16H,14-15H2,1-2H3
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2.84E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296429
PNG
(2-(4-(2-methoxybenzyl)-5-(pyridin-4-yl)-4H-1,2,4-t...)
Show SMILES COc1ccccc1Cn1c(SCC(=O)N2CCC(C)CC2)nnc1-c1ccncc1
Show InChI InChI=1S/C23H27N5O2S/c1-17-9-13-27(14-10-17)21(29)16-31-23-26-25-22(18-7-11-24-12-8-18)28(23)15-19-5-3-4-6-20(19)30-2/h3-8,11-12,17H,9-10,13-16H2,1-2H3
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3.02E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296432
PNG
(CHEMBL552272 | N-(2-(2-(2-(4-methoxyphenyl)-2-oxoe...)
Show SMILES COc1ccc(cc1)C(=O)Cn1nnc(n1)-c1ccccc1NC(=O)C1CC1
Show InChI InChI=1S/C20H19N5O3/c1-28-15-10-8-13(9-11-15)18(26)12-25-23-19(22-24-25)16-4-2-3-5-17(16)21-20(27)14-6-7-14/h2-5,8-11,14H,6-7,12H2,1H3,(H,21,27)
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3.10E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296433
PNG
(CHEMBL564664 | benzyl 2-(5-(2-fluorophenyl)-1,3,4-...)
Show SMILES Fc1ccccc1-c1nnc(SCC(=O)OCc2ccccc2)o1
Show InChI InChI=1S/C17H13FN2O3S/c18-14-9-5-4-8-13(14)16-19-20-17(23-16)24-11-15(21)22-10-12-6-2-1-3-7-12/h1-9H,10-11H2
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3.34E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81908
PNG
(3-(5-((naphthalen-1-yloxy)methyl)-4-pheny-4H-1,2,4...)
Show SMILES OC(=O)CCSc1nnc(COc2cccc3ccccc23)n1-c1ccccc1
Show InChI InChI=1S/C22H19N3O3S/c26-21(27)13-14-29-22-24-23-20(25(22)17-9-2-1-3-10-17)15-28-19-12-6-8-16-7-4-5-11-18(16)19/h1-12H,13-15H2,(H,26,27)
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3.50E+4n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296417
PNG
(CHEMBL561592 | isopropyl 2-(4-benzyl-5-(2-methoxyp...)
Show SMILES COc1ccccc1-c1nnc(SCC(=O)OC(C)C)n1Cc1ccccc1
Show InChI InChI=1S/C21H23N3O3S/c1-15(2)27-19(25)14-28-21-23-22-20(17-11-7-8-12-18(17)26-3)24(21)13-16-9-5-4-6-10-16/h4-12,15H,13-14H2,1-3H3
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3.61E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296431
PNG
(3-methyl-N-(2-methylphenethyl)-4-(1H-tetrazol-1-yl...)
Show SMILES Cc1ccccc1CCNS(=O)(=O)c1ccc(c(C)c1)-n1cnnn1
Show InChI InChI=1S/C17H19N5O2S/c1-13-5-3-4-6-15(13)9-10-19-25(23,24)16-7-8-17(14(2)11-16)22-12-18-20-21-22/h3-8,11-12,19H,9-10H2,1-2H3
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3.80E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296424
PNG
(1-(2-fluorophenyl)-2-(5-o-tolyl-1,3,4-oxadiazol-2-...)
Show SMILES Cc1ccccc1-c1nnc(SCC(=O)c2ccccc2F)o1
Show InChI InChI=1S/C17H13FN2O2S/c1-11-6-2-3-7-12(11)16-19-20-17(22-16)23-10-15(21)13-8-4-5-9-14(13)18/h2-9H,10H2,1H3
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4.00E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296416
PNG
(CHEMBL563744 | methyl 2-(4-benzyl-5-(2-hydroxyphen...)
Show SMILES COC(=O)CSc1nnc(-c2ccccc2O)n1Cc1ccccc1
Show InChI InChI=1S/C18H17N3O3S/c1-24-16(23)12-25-18-20-19-17(14-9-5-6-10-15(14)22)21(18)11-13-7-3-2-4-8-13/h2-10,22H,11-12H2,1H3
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4.16E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296434
PNG
(3-(5-(2-(2-fluorophenyl)-2-oxoethylthio)-1H-tetraz...)
Show SMILES OC(=O)c1cccc(c1)-n1nnnc1SCC(=O)c1ccccc1F
Show InChI InChI=1S/C16H11FN4O3S/c17-13-7-2-1-6-12(13)14(22)9-25-16-18-19-20-21(16)11-5-3-4-10(8-11)15(23)24/h1-8H,9H2,(H,23,24)
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5.38E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM50296435
PNG
(2-(4-benzyl-5-(3-methylphenethyl)-4H-1,2,4-triazol...)
Show SMILES Cc1cccc(CCc2nnc(SCC(O)=O)n2Cc2ccccc2)c1
Show InChI InChI=1S/C20H21N3O2S/c1-15-6-5-9-16(12-15)10-11-18-21-22-20(26-14-19(24)25)23(18)13-17-7-3-2-4-8-17/h2-9,12H,10-11,13-14H2,1H3,(H,24,25)
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5.70E+4n/an/an/an/an/an/an/an/a



Universitat Aut£noma de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of corn earworm recombinant carboxypeptidase B expressed in Pichia pastoris system


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81904
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(5thiophen-2...)
Show SMILES O=C(Cn1nnc(n1)-c1cccs1)N1CCc2ccccc2C1
Show InChI InChI=1S/C16H15N5OS/c22-15(20-8-7-12-4-1-2-5-13(12)10-20)11-21-18-16(17-19-21)14-6-3-9-23-14/h1-6,9H,7-8,10-11H2
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6.20E+4n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81909
PNG
(N-benzyl-4-fluoro-N-((4-hydroxyquinazolin-2-yl)met...)
Show SMILES Fc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)Cc1nc2ccccc2c(=O)[nH]1
Show InChI InChI=1S/C22H18FN3O3S/c23-17-10-12-18(13-11-17)30(28,29)26(14-16-6-2-1-3-7-16)15-21-24-20-9-5-4-8-19(20)22(27)25-21/h1-13H,14-15H2,(H,24,25,27)
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8.20E+4n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81902
PNG
(2-Amino-3-(1-aminoisoquinolin-6-yl)propanoic acid,...)
Show SMILES NC(Cc1ccc2c(N)nccc2c1)C(O)=O
Show InChI InChI=1S/C12H13N3O2/c13-10(12(16)17)6-7-1-2-9-8(5-7)3-4-15-11(9)14/h1-5,10H,6,13H2,(H2,14,15)(H,16,17)
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1.00E+5n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair
Carboxypeptidase B


(Helicoverpa zea (Corn earworm moth) (Heliothis zea...)
BDBM81903
PNG
(2-amino-3-(1-aminoisoquinolin-7-yl)propanoic acid,...)
Show SMILES NC(Cc1ccc2ccnc(N)c2c1)C(O)=O
Show InChI InChI=1S/C12H13N3O2/c13-10(12(16)17)6-7-1-2-8-3-4-15-11(14)9(8)5-7/h1-5,10H,6,13H2,(H2,14,15)(H,16,17)
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1.29E+5n/an/an/an/an/an/an/an/a



Universitat Autònoma de Barcelona



Assay Description
The aromatic compounds screening were characterized by molecular docking as well as by in vitro inhibition assay against carboxypeptidase(CPs) of dif...


Citation and Details
More data for this
Ligand-Target Pair