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Found 1266 hits Enz. Inhib. hit(s) with Target = 'Casein kinase II' AND taxid = 9913   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase II alpha (prime)


(Homo sapiens (human)-Homo sapiens (Human))
BDBM15211
PNG
(CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[...)
Show SMILES Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+
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1.37E+5n/an/an/an/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Inhibitory constant against bovine CK2


J Biol Chem 271: 26157-64 (1996)

More data for this
Ligand-Target Pair
Casein kinase II alpha (prime)


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50366348
PNG
(CHEMBL1233654)
Show SMILES C[C@H]1CNCCN1S(=O)(=O)c1cccc2cnccc12
Show InChI InChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3/t11-/m0/s1
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7.80E+5n/an/an/an/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Inhibitory constant against CK2


J Biol Chem 271: 26157-64 (1996)

More data for this
Ligand-Target Pair
Casein kinase II alpha (prime)


(Homo sapiens (human)-Homo sapiens (Human))
BDBM15210
PNG
(CHEMBL148333 | H-8 | Lopac-M-9656 | N-(2-methylami...)
Show SMILES CNCCNS(=O)(=O)c1cccc2cnccc12
Show InChI InChI=1S/C12H15N3O2S/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12/h2-6,9,13,15H,7-8H2,1H3
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9.50E+5n/an/an/an/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Inhibitory constant against CK2


J Biol Chem 271: 26157-64 (1996)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM218843
PNG
(US9303033, A1, Example 5)
Show SMILES Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C16H12ClN7O2/c17-9-2-1-3-10(5-9)20-13-6-12(18)24-14(22-13)8(7-19-24)4-11-15(25)23-16(26)21-11/h1-7H,18H2,(H,20,22)(H2,21,23,25,26)/b11-4-
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n/an/a<0.100n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219949
PNG
(US9303033, Z43, Table 50A, Compound 31)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(NCc3ccccc3-c3ccccc3)nc12
Show InChI InChI=1S/C26H23N7O2/c34-25-21(30-26(35)32-25)12-18-15-28-33-23(29-19-10-11-19)13-22(31-24(18)33)27-14-17-8-4-5-9-20(17)16-6-2-1-3-7-16/h1-9,12-13,15,19,29H,10-11,14H2,(H,27,31)(H2,30,32,34,35)/b21-12-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219950
PNG
(US9303033, A44, Table 50A, Compound 32)
Show SMILES Fc1ccc(Br)c(CNc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C20H17BrFN7O2/c21-14-4-1-12(22)5-10(14)8-23-16-7-17(25-13-2-3-13)29-18(27-16)11(9-24-29)6-15-19(30)28-20(31)26-15/h1,4-7,9,13,25H,2-3,8H2,(H,23,27)(H2,26,28,30,31)/b15-6-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219952
PNG
(US9303033, C44, Table 50A, Compound 34)
Show SMILES O[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1/C19H23N7O3/c27-13-5-3-11(4-6-13)21-15-8-16(22-12-1-2-12)26-17(24-15)10(9-20-26)7-14-18(28)25-19(29)23-14/h7-9,11-13,22,27H,1-6H2,(H,21,24)(H2,23,25,28,29)/b14-7-/t11-,13-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219818
PNG
(US9303033, X40, Table 43A, Compound 53 | US9303033...)
Show SMILES Clc1c(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cccc1OCCN1CCOCC1
Show InChI InChI=1S/C25H27ClN8O4/c26-22-17(2-1-3-19(22)38-11-8-33-6-9-37-10-7-33)29-20-13-21(28-16-4-5-16)34-23(31-20)15(14-27-34)12-18-24(35)32-25(36)30-18/h1-3,12-14,16,28H,4-11H2,(H,29,31)(H2,30,32,35,36)/b18-12-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219870
PNG
(US9303033, Y40, Table 43A, Compound 54)
Show SMILES Cc1ccc(Cl)c(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C20H18ClN7O2/c1-10-2-5-13(21)14(6-10)24-16-8-17(23-12-3-4-12)28-18(26-16)11(9-22-28)7-15-19(29)27-20(30)25-15/h2,5-9,12,23H,3-4H2,1H3,(H,24,26)(H2,25,27,29,30)/b15-7-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219871
PNG
(US9303033, Z40, Table 43A, Compound 55)
Show SMILES CCN1CCN(CC1)c1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1
Show InChI InChI=1S/C25H29N9O2/c1-2-32-9-11-33(12-10-32)19-7-5-17(6-8-19)27-21-14-22(28-18-3-4-18)34-23(30-21)16(15-26-34)13-20-24(35)31-25(36)29-20/h5-8,13-15,18,28H,2-4,9-12H2,1H3,(H,27,30)(H2,29,31,35,36)/b20-13-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219872
PNG
(US9303033, A41, Table 43A, Compound 56)
Show SMILES Clc1cc(ccc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)N1CCOCC1
Show InChI InChI=1S/C23H23ClN8O3/c24-16-10-15(31-5-7-35-8-6-31)3-4-17(16)27-19-11-20(26-14-1-2-14)32-21(29-19)13(12-25-32)9-18-22(33)30-23(34)28-18/h3-4,9-12,14,26H,1-2,5-8H2,(H,27,29)(H2,28,30,33,34)/b18-9-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219873
PNG
(US9303033, B41, Table 43A, Compound 57)
Show SMILES CC(C)(C)OC(=O)NCc1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1
Show InChI InChI=1S/C25H28N8O4/c1-25(2,3)37-24(36)26-12-14-4-6-16(7-5-14)28-19-11-20(29-17-8-9-17)33-21(31-19)15(13-27-33)10-18-22(34)32-23(35)30-18/h4-7,10-11,13,17,29H,8-9,12H2,1-3H3,(H,26,36)(H,28,31)(H2,30,32,34,35)/b18-10-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219874
PNG
(US9303033, C41, Table 43A, Compound 58)
Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1
Show InChI InChI=1S/C28H33N9O4/c1-28(2,3)41-27(40)36-12-10-35(11-13-36)20-8-6-18(7-9-20)30-22-15-23(31-19-4-5-19)37-24(33-22)17(16-29-37)14-21-25(38)34-26(39)32-21/h6-9,14-16,19,31H,4-5,10-13H2,1-3H3,(H,30,33)(H2,32,34,38,39)/b21-14-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219875
PNG
(US9303033, D41, Table 43A, Compound 59)
Show SMILES COc1ccc(F)cc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C20H18FN7O3/c1-31-15-5-2-11(21)7-13(15)24-16-8-17(23-12-3-4-12)28-18(26-16)10(9-22-28)6-14-19(29)27-20(30)25-14/h2,5-9,12,23H,3-4H2,1H3,(H,24,26)(H2,25,27,29,30)/b14-6-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219876
PNG
(US9303033, E41, Table 43A, Compound 60)
Show SMILES COc1ccc(C)cc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C21H21N7O3/c1-11-3-6-16(31-2)14(7-11)24-17-9-18(23-13-4-5-13)28-19(26-17)12(10-22-28)8-15-20(29)27-21(30)25-15/h3,6-10,13,23H,4-5H2,1-2H3,(H,24,26)(H2,25,27,29,30)/b15-8-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219877
PNG
(US9303033, F41, Table 43A, Compound 61)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1
Show InChI InChI=1S/C29H34N8O4/c1-29(2,3)41-28(40)36-12-10-18(11-13-36)17-4-6-20(7-5-17)31-23-15-24(32-21-8-9-21)37-25(34-23)19(16-30-37)14-22-26(38)35-27(39)33-22/h4-7,14-16,18,21,32H,8-13H2,1-3H3,(H,31,34)(H2,33,35,38,39)/b22-14-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219878
PNG
(US9303033, G41, Table 43A, Compound 62)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccc(cc3)N3CCNCC3)nc12
Show InChI InChI=1S/C23H25N9O2/c33-22-18(28-23(34)30-22)11-14-13-25-32-20(27-16-1-2-16)12-19(29-21(14)32)26-15-3-5-17(6-4-15)31-9-7-24-8-10-31/h3-6,11-13,16,24,27H,1-2,7-10H2,(H,26,29)(H2,28,30,33,34)/b18-11-
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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219879
PNG
(US9303033, H41, Table 43A, Compound 63)
Show SMILES NCc1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1
Show InChI InChI=1S/C20H20N8O2/c21-9-11-1-3-13(4-2-11)23-16-8-17(24-14-5-6-14)28-18(26-16)12(10-22-28)7-15-19(29)27-20(30)25-15/h1-4,7-8,10,14,24H,5-6,9,21H2,(H,23,26)(H2,25,27,29,30)/b15-7-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219880
PNG
(US9303033, I41, Table 43A, Compound 64)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccc(cc3)C3CCNCC3)nc12
Show InChI InChI=1S/C24H26N8O2/c33-23-19(29-24(34)31-23)11-16-13-26-32-21(28-18-5-6-18)12-20(30-22(16)32)27-17-3-1-14(2-4-17)15-7-9-25-10-8-15/h1-4,11-13,15,18,25,28H,5-10H2,(H,27,30)(H2,29,31,33,34)/b19-11-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219881
PNG
(US9303033, J41, Table 44A, Compound 1)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1
Show InChI InChI=1S/C25H26FN9O3/c1-33-6-8-34(9-7-33)24(37)14-2-5-18(17(26)10-14)29-20-12-21(28-16-3-4-16)35-22(31-20)15(13-27-35)11-19-23(36)32-25(38)30-19/h2,5,10-13,16,28H,3-4,6-9H2,1H3,(H,29,31)(H2,30,32,36,38)/b19-11-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219882
PNG
(US9303033, K41, Table 44A, Compound 2)
Show SMILES Fc1cc(ccc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C(=O)NC1CC1
Show InChI InChI=1S/C23H21FN8O3/c24-15-7-11(21(33)27-14-4-5-14)1-6-16(15)28-18-9-19(26-13-2-3-13)32-20(30-18)12(10-25-32)8-17-22(34)31-23(35)29-17/h1,6-10,13-14,26H,2-5H2,(H,27,33)(H,28,30)(H2,29,31,34,35)/b17-8-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219883
PNG
(US9303033, L41, Table 44A, Compound 3)
Show SMILES Fc1cc(ccc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C(=O)N1CCCNCC1
Show InChI InChI=1S/C25H26FN9O3/c26-17-10-14(24(37)34-8-1-6-27-7-9-34)2-5-18(17)30-20-12-21(29-16-3-4-16)35-22(32-20)15(13-28-35)11-19-23(36)33-25(38)31-19/h2,5,10-13,16,27,29H,1,3-4,6-9H2,(H,30,32)(H2,31,33,36,38)/b19-11-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219884
PNG
(US9303033, M41, Table 44A, Compound 4)
Show SMILES CN1CCC(CC1)NC(=O)c1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1
Show InChI InChI=1S/C26H28FN9O3/c1-35-8-6-17(7-9-35)30-24(37)14-2-5-19(18(27)10-14)31-21-12-22(29-16-3-4-16)36-23(33-21)15(13-28-36)11-20-25(38)34-26(39)32-20/h2,5,10-13,16-17,29H,3-4,6-9H2,1H3,(H,30,37)(H,31,33)(H2,32,34,38,39)/b20-11-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219886
PNG
(US9303033, O41, Table 44A, Compound 6)
Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1
Show InChI InChI=1/C26H27FN8O4/c1-13-11-34(12-14(2)39-13)25(37)15-3-6-19(18(27)7-15)30-21-9-22(29-17-4-5-17)35-23(32-21)16(10-28-35)8-20-24(36)33-26(38)31-20/h3,6-10,13-14,17,29H,4-5,11-12H2,1-2H3,(H,30,32)(H2,31,33,36,38)/b20-8-/t13-,14+
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219888
PNG
(US9303033, Q41, Table 44A, Compound 8)
Show SMILES CNC(=O)c1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1
Show InChI InChI=1S/C21H19FN8O3/c1-23-19(31)10-2-5-14(13(22)6-10)26-16-8-17(25-12-3-4-12)30-18(28-16)11(9-24-30)7-15-20(32)29-21(33)27-15/h2,5-9,12,25H,3-4H2,1H3,(H,23,31)(H,26,28)(H2,27,29,32,33)/b15-7-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219890
PNG
(US9303033, S41, Table 45A, Compound 2)
Show SMILES Fc1ccc(Br)cc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C19H15BrFN7O2/c20-10-1-4-12(21)13(6-10)24-15-7-16(23-11-2-3-11)28-17(26-15)9(8-22-28)5-14-18(29)27-19(30)25-14/h1,4-8,11,23H,2-3H2,(H,24,26)(H2,25,27,29,30)/b14-5-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219891
PNG
(US9303033, T41, Table 45A, Compound 3)
Show SMILES Clc1cc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1C#N
Show InChI InChI=1S/C20H15ClN8O2/c21-14-6-13(2-1-10(14)8-22)24-16-7-17(25-12-3-4-12)29-18(27-16)11(9-23-29)5-15-19(30)28-20(31)26-15/h1-2,5-7,9,12,25H,3-4H2,(H,24,27)(H2,26,28,30,31)/b15-5-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219892
PNG
(US9303033, U41, Table 45A, Compound 4)
Show SMILES Fc1cc(Br)ccc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C19H15BrFN7O2/c20-10-1-4-13(12(21)6-10)24-15-7-16(23-11-2-3-11)28-17(26-15)9(8-22-28)5-14-18(29)27-19(30)25-14/h1,4-8,11,23H,2-3H2,(H,24,26)(H2,25,27,29,30)/b14-5-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219893
PNG
(US9303033, V41, Table 45A, Compound 5)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccc(cc3)C#N)nc12
Show InChI InChI=1S/C20H16N8O2/c21-9-11-1-3-13(4-2-11)23-16-8-17(24-14-5-6-14)28-18(26-16)12(10-22-28)7-15-19(29)27-20(30)25-15/h1-4,7-8,10,14,24H,5-6H2,(H,23,26)(H2,25,27,29,30)/b15-7-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219894
PNG
(US9303033, W41, Table 46A, Compound 1)
Show SMILES Fc1c(Br)cccc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C19H15BrFN7O2/c20-11-2-1-3-12(16(11)21)24-14-7-15(23-10-4-5-10)28-17(26-14)9(8-22-28)6-13-18(29)27-19(30)25-13/h1-3,6-8,10,23H,4-5H2,(H,24,26)(H2,25,27,29,30)/b13-6-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219895
PNG
(US9303033, X41, Table 46A, Compound 2)
Show SMILES Clc1ccc(cc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N
Show InChI InChI=1S/C20H15ClN8O2/c21-13-4-1-10(8-22)5-14(13)25-16-7-17(24-12-2-3-12)29-18(27-16)11(9-23-29)6-15-19(30)28-20(31)26-15/h1,4-7,9,12,24H,2-3H2,(H,25,27)(H2,26,28,30,31)/b15-6-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219896
PNG
(US9303033, Y41, Table 46A, Compound 3)
Show SMILES Clc1cc(cnc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N
Show InChI InChI=1S/C19H14ClN9O2/c20-12-3-9(6-21)7-22-16(12)26-14-5-15(24-11-1-2-11)29-17(27-14)10(8-23-29)4-13-18(30)28-19(31)25-13/h3-5,7-8,11,24H,1-2H2,(H,22,26,27)(H2,25,28,30,31)/b13-4-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219897
PNG
(US9303033, Z41, Table 46A, Compound 4)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccc(cn3)-n3ccnc3)nc12
Show InChI InChI=1S/C21H18N10O2/c32-20-15(26-21(33)29-20)7-12-9-24-31-18(25-13-1-2-13)8-17(28-19(12)31)27-16-4-3-14(10-23-16)30-6-5-22-11-30/h3-11,13,25H,1-2H2,(H,23,27,28)(H2,26,29,32,33)/b15-7-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219898
PNG
(US9303033, A42, Table 46A, Compound 5)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccccc3C#N)nc12
Show InChI InChI=1S/C20H16N8O2/c21-9-11-3-1-2-4-14(11)24-16-8-17(23-13-5-6-13)28-18(26-16)12(10-22-28)7-15-19(29)27-20(30)25-15/h1-4,7-8,10,13,23H,5-6H2,(H,24,26)(H2,25,27,29,30)/b15-7-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219899
PNG
(US9303033, B42, Table 46A, Compound 6)
Show SMILES Brc1cc(ccc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N
Show InChI InChI=1S/C20H15BrN8O2/c21-13-5-10(8-22)1-4-14(13)25-16-7-17(24-12-2-3-12)29-18(27-16)11(9-23-29)6-15-19(30)28-20(31)26-15/h1,4-7,9,12,24H,2-3H2,(H,25,27)(H2,26,28,30,31)/b15-6-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219900
PNG
(US9303033, C42, Table 46A, Compound 7)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccc(cn3)C#N)nc12
Show InChI InChI=1S/C19H15N9O2/c20-7-10-1-4-14(21-8-10)25-15-6-16(23-12-2-3-12)28-17(26-15)11(9-22-28)5-13-18(29)27-19(30)24-13/h1,4-6,8-9,12,23H,2-3H2,(H,21,25,26)(H2,24,27,29,30)/b13-5-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219347
PNG
(US9303033, U20, Table 37A, Compound 21)
Show SMILES C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(Cl)c1
Show InChI InChI=1/C20H19ClN8O2/c1-10(11-3-2-4-13(21)7-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-5-6-14/h2-4,7-10,14H,5-6H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/s2
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219349
PNG
(US9303033, W20, Table 37A, Compound 23)
Show SMILES CCOCC1(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1
Show InChI InChI=1S/C19H24N8O3/c1-2-30-10-19(5-6-19)9-20-16-24-14-11(7-13-15(28)25-18(29)23-13)8-21-27(14)17(26-16)22-12-3-4-12/h7-8,12H,2-6,9-10H2,1H3,(H2,20,22,24,26)(H2,23,25,28,29)/b13-7-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219351
PNG
(US9303033, Y20, Table 37A, Compound 25)
Show SMILES COCCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C15H18N8O3/c1-26-5-4-16-13-20-11-8(6-10-12(24)21-15(25)19-10)7-17-23(11)14(22-13)18-9-2-3-9/h6-7,9H,2-5H2,1H3,(H2,16,18,20,22)(H2,19,21,24,25)/b10-6-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219353
PNG
(US9303033, B21, Table 37A, Compound 27)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3(Cn4ccnc4)CC3)nc12
Show InChI InChI=1S/C20H22N10O2/c31-16-14(25-19(32)27-16)7-12-8-23-30-15(12)26-17(28-18(30)24-13-1-2-13)22-9-20(3-4-20)10-29-6-5-21-11-29/h5-8,11,13H,1-4,9-10H2,(H2,22,24,26,28)(H2,25,27,31,32)/b14-7-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219355
PNG
(US9303033, D21, Table 37A, Compound 29)
Show SMILES CS(=O)(=O)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C20H20N8O4S/c1-33(31,32)14-4-2-3-11(7-14)9-21-18-25-16-12(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-13-5-6-13/h2-4,7-8,10,13H,5-6,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219362
PNG
(US9303033, K21, Table 37A, Compound 36)
Show SMILES CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1F
Show InChI InChI=1/C20H19FN8O2/c1-10(13-4-2-3-5-14(13)21)23-18-26-16-11(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-12-6-7-12/h2-5,8-10,12H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219372
PNG
(US9303033, U21, Table 37A, Compound 46)
Show SMILES CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc2OCOc2c1
Show InChI InChI=1/C21H20N8O4/c1-10(11-2-5-15-16(7-11)33-9-32-15)23-19-26-17-12(6-14-18(30)27-21(31)25-14)8-22-29(17)20(28-19)24-13-3-4-13/h2,5-8,10,13H,3-4,9H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b14-6-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219373
PNG
(US9303033, V21, Table 37A, Compound 47)
Show SMILES Cc1ccc(F)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1Cl
Show InChI InChI=1S/C20H18ClFN8O2/c1-9-2-5-13(22)12(15(9)21)8-23-18-27-16-10(6-14-17(31)28-20(32)26-14)7-24-30(16)19(29-18)25-11-3-4-11/h2,5-7,11H,3-4,8H2,1H3,(H2,23,25,27,29)(H2,26,28,31,32)/b14-6-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219374
PNG
(US9303033, W21, Table 37A, Compound 48)
Show SMILES CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(F)cc(F)c1
Show InChI InChI=1/C20H18F2N8O2/c1-9(10-4-12(21)7-13(22)5-10)24-18-27-16-11(6-15-17(31)28-20(32)26-15)8-23-30(16)19(29-18)25-14-2-3-14/h4-9,14H,2-3H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b15-6-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219377
PNG
(US9303033, Z21, Table 37A, Compound 51)
Show SMILES Cn1c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)nc2ccccc12
Show InChI InChI=1S/C21H20N10O2/c1-30-15-5-3-2-4-13(15)25-16(30)10-22-19-27-17-11(8-14-18(32)28-21(33)26-14)9-23-31(17)20(29-19)24-12-6-7-12/h2-5,8-9,12H,6-7,10H2,1H3,(H2,22,24,27,29)(H2,26,28,32,33)/b14-8-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219378
PNG
(US9303033, A22, Table 37A, Compound 52)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3N3CCOCC3)nc12
Show InChI InChI=1S/C23H25N9O3/c33-20-17(27-23(34)29-20)11-15-13-25-32-19(15)28-21(30-22(32)26-16-5-6-16)24-12-14-3-1-2-4-18(14)31-7-9-35-10-8-31/h1-4,11,13,16H,5-10,12H2,(H2,24,26,28,30)(H2,27,29,33,34)/b17-11-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219381
PNG
(US9303033, D22, Table 37A, Compound 55)
Show SMILES Fc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1
Show InChI InChI=1S/C19H16ClFN8O2/c20-13-6-11(21)2-1-9(13)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219386
PNG
(US9303033, I22, Table 37A, Compound 60)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccsc3)nc12
Show InChI InChI=1S/C17H16N8O2S/c26-14-12(21-17(27)23-14)5-10-7-19-25-13(10)22-15(18-6-9-3-4-28-8-9)24-16(25)20-11-1-2-11/h3-5,7-8,11H,1-2,6H2,(H2,18,20,22,24)(H2,21,23,26,27)/b12-5-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM219904
PNG
(US9303033, G42, Example 254)
Show SMILES OCN1C(=O)N\C(=C/c2cnn3c(NC4CC4)cc(Nc4cc(Cl)ccc4F)nc23)C1=O
Show InChI InChI=1S/C20H17ClFN7O3/c21-11-1-4-13(22)14(6-11)25-16-7-17(24-12-2-3-12)29-18(27-16)10(8-23-29)5-15-19(31)28(9-30)20(32)26-15/h1,4-8,12,24,30H,2-3,9H2,(H,25,27)(H,26,32)/b15-5-
PDB

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n/an/a<10n/an/an/an/an/an/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)

More data for this
Ligand-Target Pair
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