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Compile Data Set for Download or QSAR

Found 45 hits Enz. Inhib. hit(s) with Target = 'Choline transporter' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Choline transporter


(Mus musculus)
BDBM50416502
PNG
(CHEMBL1209654)
Show SMILES CCCCC[N+]1(CCC#Cc2cc(OC)c(OC)c(OC)c2)CCCCC1
Show InChI InChI=1S/C23H36NO3/c1-5-6-9-14-24(15-10-7-11-16-24)17-12-8-13-20-18-21(25-2)23(27-4)22(19-20)26-3/h18-19H,5-7,9-12,14-17H2,1-4H3/q+1
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20.0n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416489
PNG
(CHEMBL1209507)
Show SMILES COc1cc(cc(OC)c1OC)C#CCC[N+]12CCC(CC1)C2
Show InChI InChI=1S/C19H26NO3/c1-21-17-12-16(13-18(22-2)19(17)23-3)6-4-5-9-20-10-7-15(14-20)8-11-20/h12-13,15H,5,7-11,14H2,1-3H3/q+1
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50n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416490
PNG
(CHEMBL1209508)
Show SMILES COc1cc(cc(OC)c1OC)C#CCC[N+]12CCC(CC1)CC2
Show InChI InChI=1S/C20H28NO3/c1-22-18-14-17(15-19(23-2)20(18)24-3)6-4-5-10-21-11-7-16(8-12-21)9-13-21/h14-16H,5,7-13H2,1-3H3/q+1
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90.0n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416491
PNG
(CHEMBL1209577)
Show SMILES CC[N+]1(CCC#Cc2cc(OC)c(OC)c(OC)c2)CCCCC1
Show InChI InChI=1S/C20H30NO3/c1-5-21(12-8-6-9-13-21)14-10-7-11-17-15-18(22-2)20(24-4)19(16-17)23-3/h15-16H,5-6,8-10,12-14H2,1-4H3/q+1
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180n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416508
PNG
(CHEMBL1209578)
Show SMILES CC[N+]1(CCC#Cc2cc(OC)c(OC)c(OC)c2)CCCC1
Show InChI InChI=1S/C19H28NO3/c1-5-20(12-8-9-13-20)11-7-6-10-16-14-17(21-2)19(23-4)18(15-16)22-3/h14-15H,5,7-9,11-13H2,1-4H3/q+1
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200n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416504
PNG
(CHEMBL1209579)
Show SMILES CCCCCCCC[N+]1(CCC#Cc2cc(OC)c(OC)c(OC)c2)CCCCC1
Show InChI InChI=1S/C26H42NO3/c1-5-6-7-8-9-12-17-27(18-13-10-14-19-27)20-15-11-16-23-21-24(28-2)26(30-4)25(22-23)29-3/h21-22H,5-10,12-15,17-20H2,1-4H3/q+1
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230n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416506
PNG
(CHEMBL1209581)
Show SMILES C[N+]12CCC(CC1)C(=O)C2
Show InChI InChI=1S/C8H14NO/c1-9-4-2-7(3-5-9)8(10)6-9/h7H,2-6H2,1H3/q+1
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521n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416503
PNG
(CHEMBL1209713)
Show SMILES OCC[N+]12CCC(CC1)CC2
Show InChI InChI=1S/C9H18NO/c11-8-7-10-4-1-9(2-5-10)3-6-10/h9,11H,1-8H2/q+1
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640n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026220
PNG
(2-hydroxy-N,N,N-trimethylethanaminium | CHEMBL2824...)
Show SMILES C[N+](C)(C)CCO
Show InChI InChI=1S/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+1
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681n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416501
PNG
(CHEMBL1209653)
Show SMILES CC[N+](CC)(CC)CCC#Cc1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C19H30NO3/c1-7-20(8-2,9-3)13-11-10-12-16-14-17(21-4)19(23-6)18(15-16)22-5/h14-15H,7-9,11,13H2,1-6H3/q+1
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701n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416488
PNG
(CHEMBL1209506)
Show SMILES COc1cc(cc(OC)c1OC)C#CCC[N+](C)(C)C
Show InChI InChI=1S/C16H24NO3/c1-17(2,3)10-8-7-9-13-11-14(18-4)16(20-6)15(12-13)19-5/h11-12H,8,10H2,1-6H3/q+1
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2.00E+3n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50147119
PNG
((3-Hydroxy-propyl)-trimethyl-ammonium | CHEMBL1209...)
Show SMILES C[N+](C)(C)CCCO
Show InChI InChI=1S/C6H16NO/c1-7(2,3)5-4-6-8/h8H,4-6H2,1-3H3/q+1
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2.20E+3n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50204415
PNG
(1-methyl-1-azonia-bicyclo[2.2.2]octane | CHEMBL120...)
Show SMILES C[N+]12CCC(CC1)CC2
Show InChI InChI=1S/C8H16N/c1-9-5-2-8(3-6-9)4-7-9/h8H,2-7H2,1H3/q+1
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4.70E+3n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50079455
PNG
(CHEMBL46486 | TETRAMETHYLAMMONIUM | tetramethylamm...)
Show SMILES C[N+](C)(C)C
Show InChI InChI=1S/C4H12N/c1-5(2,3)4/h1-4H3/q+1
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3.01E+4n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM80992
PNG
(1-cetylpyridin-1-ium;bromide | 1-hexadecylpyridin-...)
Show SMILES CCCCCCCCCCCCCCCC[n+]1ccccc1
Show InChI InChI=1S/C21H38N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22/h15,17-18,20-21H,2-14,16,19H2,1H3/q+1
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3.21E+4n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416495
PNG
(CHEMBL1209648)
Show SMILES C1CN2CCC1CC2
Show InChI InChI=1S/C7H13N/c1-4-8-5-2-7(1)3-6-8/h7H,1-6H2
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4.01E+4n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50060526
PNG
(2-Dimethylamino-ethanol | 2-hydroxy-N,N-dimethylet...)
Show SMILES CN(C)CCO
Show InChI InChI=1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3
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5.57E+4n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416507
PNG
(CHEMBL1209649)
Show SMILES C[N+]12CCC(O)(CC1)CC2
Show InChI InChI=1S/C8H16NO/c1-9-5-2-8(10,3-6-9)4-7-9/h10H,2-7H2,1H3/q+1
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7.21E+4n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM80386
PNG
(CHEMBL1209421 | MLS000069658 | PHENYLTRIMETHYLAMMO...)
Show SMILES C[N+](C)(C)c1ccccc1
Show InChI InChI=1S/C9H14N/c1-10(2,3)9-7-5-4-6-8-9/h4-8H,1-3H3/q+1
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7.52E+4n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416505
PNG
(CHEMBL1209580)
Show SMILES Cc1cc(C)nc(C)c1
Show InChI InChI=1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3
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1.07E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416484
PNG
(CHEMBL1209503)
Show SMILES CC(=O)OCCC[N+](C)(C)C
Show InChI InChI=1S/C8H18NO2/c1-8(10)11-7-5-6-9(2,3)4/h5-7H2,1-4H3/q+1
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1.90E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416496
PNG
(CHEMBL1209650)
Show SMILES CC1C(O)C2CC[N+]1(C)CC2
Show InChI InChI=1S/C9H18NO/c1-7-9(11)8-3-5-10(7,2)6-4-8/h7-9,11H,3-6H2,1-2H3/q+1
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2.10E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50047005
PNG
(1-Aza-bicyclo[2.2.2]octan-3-ol | 1-Aza-bicyclo[2.2...)
Show SMILES OC1CN2CCC1CC2
Show InChI InChI=1S/C7H13NO/c9-7-5-8-3-1-6(7)2-4-8/h6-7,9H,1-5H2
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2.10E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50149890
PNG
(CHEMBL9324 | tetraethylammonium)
Show SMILES CC[N+](CC)(CC)CC
Show InChI InChI=1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1
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2.60E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416485
PNG
(CHEMBL1209504)
Show SMILES COC(=O)CC[N+](C)(C)C
Show InChI InChI=1S/C7H16NO2/c1-8(2,3)6-5-7(9)10-4/h5-6H2,1-4H3/q+1
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2.70E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416483
PNG
(CHEMBL1209424)
Show SMILES CN(C)CCCO
Show InChI InChI=1S/C5H13NO/c1-6(2)4-3-5-7/h7H,3-5H2,1-2H3
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2.90E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50147105
PNG
((4-Hydroxy-butyl)-trimethyl-ammonium | CHEMBL10228...)
Show SMILES C[N+](C)(C)CCCCO
Show InChI InChI=1S/C7H18NO/c1-8(2,3)6-4-5-7-9/h9H,4-7H2,1-3H3/q+1
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3.10E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416486
PNG
(CHEMBL1209505)
Show SMILES CCOC(=O)CC[N+](C)(C)C
Show InChI InChI=1S/C8H18NO2/c1-5-11-8(10)6-7-9(2,3)4/h5-7H2,1-4H3/q+1
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3.40E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416499
PNG
(TRIMETHYLAMMONIUM)
Show InChI InChI=1S/C3H9N/c1-4(2)3/h1-3H3
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3.40E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416500
PNG
(CHEMBL1209652)
Show SMILES C[n+]1cccc(c1)C(N)=O
Show InChI InChI=1S/C7H8N2O/c1-9-4-2-3-6(5-9)7(8)10/h2-5H,1H3,(H-,8,10)/p+1
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3.61E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM10458
PNG
(4-AP | 4-Aminopyridine 10 | CHEMBL284348 | DALFAMP...)
Show SMILES Nc1ccncc1
Show InChI InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
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4.81E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50004108
PNG
((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...)
Show SMILES CN1CCCC1c1cccnc1
Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3
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5.20E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416493
PNG
(CHEMBL354077)
Show SMILES Nc1ccncc1N
Show InChI InChI=1S/C5H7N3/c6-4-1-2-8-3-5(4)7/h1-3H,7H2,(H2,6,8)
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8.20E+5n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416487
PNG
(CHEMBL1236196 | TETRABUTYLAMMONIUM)
Show SMILES CCCC[N+](CCCC)(CCCC)CCCC
Show InChI InChI=1S/C16H36N/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4/h5-16H2,1-4H3/q+1
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1.05E+6n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50147120
PNG
(2-Methylamino-ethanol | 2-hydroxy-N-methylethanami...)
Show InChI InChI=1S/C3H9NO/c1-4-2-3-5/h4-5H,2-3H2,1H3
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3.80E+6n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416497
PNG
(DIMETHYLAMINE)
Show InChI InChI=1S/C2H7N/c1-3-2/h3H,1-2H3
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9.42E+6n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50416492
PNG
(Integrase inhibitor, R3{3} | METHYLAMINE)
Show InChI InChI=1S/CH5N/c1-2/h2H2,1H3
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3.51E+7n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM7973
PNG
(2-aminoethan-1-ol | CHEMBL104943 | ethanolamine)
Show InChI InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2
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1.50E+8n/an/an/an/an/an/an/an/a



Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosome


Citation and Details
More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026216
PNG
(1-Ethyl-1-(2-hydroxy-ethyl)-aziridinium; chloride ...)
Show SMILES CC[N+]1(CCO)CC1
Show InChI InChI=1S/C6H14NO/c1-2-7(3-4-7)5-6-8/h8H,2-6H2,1H3/q+1
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n/an/a 1.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT


J Med Chem 29: 376-80 (1986)

More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026220
PNG
(2-hydroxy-N,N,N-trimethylethanaminium | CHEMBL2824...)
Show SMILES C[N+](C)(C)CCO
Show InChI InChI=1S/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+1
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n/an/a 1.60E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT


J Med Chem 29: 376-80 (1986)

More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026218
PNG
(1-(2-Hydroxy-ethyl)-1-isopropyl-aziridinium; chlor...)
Show SMILES CC(C)[N+]1(CCO)CC1
Show InChI InChI=1S/C7H16NO/c1-7(2)8(3-4-8)5-6-9/h7,9H,3-6H2,1-2H3/q+1
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n/an/a 2.60E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT


J Med Chem 29: 376-80 (1986)

More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026215
PNG
(1-Cyclopropyl-1-(2-hydroxy-ethyl)-aziridinium; chl...)
Show SMILES OCC[N+]1(CC1)C1CC1
Show InChI InChI=1S/C7H14NO/c9-6-5-8(3-4-8)7-1-2-7/h7,9H,1-6H2/q+1
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n/an/a 3.90E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT


J Med Chem 29: 376-80 (1986)

More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026219
PNG
(1-(2-Hydroxy-ethyl)-1-propyl-aziridinium; chloride...)
Show SMILES CCC[N+]1(CCO)CC1
Show InChI InChI=1S/C7H16NO/c1-2-3-8(4-5-8)6-7-9/h9H,2-7H2,1H3/q+1
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n/an/a 7.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT


J Med Chem 29: 376-80 (1986)

More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026217
PNG
(1-(2-Hydroxy-ethyl)-1-isobutyl-aziridinium; chlori...)
Show SMILES CC(C)C[N+]1(CCO)CC1
Show InChI InChI=1S/C8H18NO/c1-8(2)7-9(3-4-9)5-6-10/h8,10H,3-7H2,1-2H3/q+1
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n/an/a 3.10E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT


J Med Chem 29: 376-80 (1986)

More data for this
Ligand-Target Pair
Choline transporter


(Mus musculus)
BDBM50026221
PNG
(1-Butyl-1-(2-hydroxy-ethyl)-aziridinium; chloride ...)
Show SMILES CCCC[N+]1(CCO)CC1
Show InChI InChI=1S/C8H18NO/c1-2-3-4-9(5-6-9)7-8-10/h10H,2-8H2,1H3/q+1
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n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for its ability to inhibit the transport of [3H]-choline in to high affinity choline transport system HAChT


J Med Chem 29: 376-80 (1986)

More data for this
Ligand-Target Pair