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Found 8 hits Enz. Inhib. hit(s) with Target = 'Cystathionine beta-synthase' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cystathionine beta-synthase


(Homo sapiens)
BDBM50064289
PNG
(CHEMBL3403661)
Show SMILES COc1cc(\C=C2/NC(=S)NC2=O)ccc1OC(C)=O
Show InChI InChI=1S/C13H12N2O4S/c1-7(16)19-10-4-3-8(6-11(10)18-2)5-9-12(17)15-13(20)14-9/h3-6H,1-2H3,(H2,14,15,17,20)/b9-5-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

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Article
PubMed
n/an/a 8.30E+4n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair
Cystathionine beta-synthase


(Homo sapiens)
BDBM50064264
PNG
(CHEMBL3403662)
Show SMILES COc1cc(\C=C2/N=C(SC)N(C)C2=O)ccc1O
Show InChI InChI=1S/C13H14N2O3S/c1-15-12(17)9(14-13(15)19-3)6-8-4-5-10(16)11(7-8)18-2/h4-7,16H,1-3H3/b9-6-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.70E+4n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair
Cystathionine beta-synthase


(Homo sapiens)
BDBM50064292
PNG
(RUBROLIDE A | Rubrolide A)
Show SMILES Oc1c(Br)cc(\C=C2/OC(=O)C=C2c2cc(Br)c(O)c(Br)c2)cc1Br
Show InChI InChI=1S/C17H8Br4O4/c18-10-1-7(2-11(19)16(10)23)3-14-9(6-15(22)25-14)8-4-12(20)17(24)13(21)5-8/h1-6,23-24H/b14-3-
PDB

UniProtKB/SwissProt

GoogleScholar
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PC sid
UniChem

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Article
PubMed
n/an/a 1.08E+5n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair
Cystathionine beta-synthase


(Homo sapiens)
BDBM50064290
PNG
(CHEMBL1956805)
Show SMILES Oc1ccc(\C=C2/NC(=S)NC2=O)cc1O
Show InChI InChI=1S/C10H8N2O3S/c13-7-2-1-5(4-8(7)14)3-6-9(15)12-10(16)11-6/h1-4,13-14H,(H2,11,12,15,16)/b6-3-
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair
Cystathionine beta-synthase


(Homo sapiens)
BDBM50064263
PNG
(CHEMBL3403663)
Show SMILES [Na+].C[C@@]12CCC(=O)c3coc(c13)C(=O)c1cc3cccc(OS([O-])(=O)=O)c3cc21
Show InChI InChI=1/C20H14O7S.Na/c1-20-6-5-15(21)13-9-26-19(17(13)20)18(22)12-7-10-3-2-4-16(27-28(23,24)25)11(10)8-14(12)20;/h2-4,7-9H,5-6H2,1H3,(H,23,24,25);/q;+1/p-1/t20-;/s2
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.36E+5n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair
Cystathionine beta-synthase


(Homo sapiens)
BDBM50108773
PNG
(4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide | 4...)
Show SMILES NC(=O)c1cc(Br)c(Br)[nH]1
Show InChI InChI=1S/C5H4Br2N2O/c6-2-1-3(5(8)10)9-4(2)7/h1,9H,(H2,8,10)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.56E+5n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair
Cystathionine beta-synthase


(Homo sapiens)
BDBM50064265
PNG
(CHEMBL1956777)
Show SMILES O=C1NC(=S)N\C1=C/c1ccccc1
Show InChI InChI=1S/C10H8N2OS/c13-9-8(11-10(14)12-9)6-7-4-2-1-3-5-7/h1-6H,(H2,11,12,13,14)/b8-6-
PDB

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.70E+5n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair
Cystathionine beta-synthase


(Homo sapiens)
BDBM50064291
PNG
(CHEMBL1957775)
Show SMILES COc1cc(\C=C2/NC(=S)NC2=O)ccc1O
Show InChI InChI=1S/C11H10N2O3S/c1-16-9-5-6(2-3-8(9)14)4-7-10(15)13-11(17)12-7/h2-5,14H,1H3,(H2,12,13,15,17)/b7-4-
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 1.87E+5n/an/an/an/an/an/a



University of Utah

Curated by ChEMBL


Assay Description
Inhibition of full-length wild-type cystathionine beta-synthase (unknown origin) assessed as inhibition of H2S production by fluorescence assay in pr...


Citation and Details
More data for this
Ligand-Target Pair