BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Cysteine proteinase B' AND taxid = 5665   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteine proteinase B


(Leishmania mexicana)
BDBM50134127
PNG
(CHEMBL607122)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N1NC[C@@H]2[C@H]1C(=O)CN2C(=O)c1ccccc1
Show InChI InChI=1/C29H36N4O4/c1-18(2)15-22(31-26(35)19-11-13-21(14-12-19)29(3,4)5)28(37)33-25-23(16-30-33)32(17-24(25)34)27(36)20-9-7-6-8-10-20/h6-14,18,22-23,25,30H,15-17H2,1-5H3,(H,31,35)/t22-,23+,25-/s2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
50n/an/an/an/an/an/an/an/a



Amura Therapeutics Limited, Inc

Curated by ChEMBL


Assay Description
Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)


Citation and Details
More data for this
Ligand-Target Pair
Cysteine proteinase B


(Leishmania mexicana)
BDBM50318879
PNG
(CHEMBL607169 | N-((S)-1-((3aR,6aS)-4-benzoyl-6-oxo...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N1CC[C@@H]2[C@H]1C(=O)CN2C(=O)c1ccccc1
Show InChI InChI=1S/C30H37N3O4/c1-19(2)17-23(31-27(35)20-11-13-22(14-12-20)30(3,4)5)29(37)32-16-15-24-26(32)25(34)18-33(24)28(36)21-9-7-6-8-10-21/h6-14,19,23-24,26H,15-18H2,1-5H3,(H,31,35)/t23-,24+,26-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
691n/an/an/an/an/an/an/an/a



Amura Therapeutics Limited, Inc

Curated by ChEMBL


Assay Description
Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)


Citation and Details
More data for this
Ligand-Target Pair
Cysteine proteinase B


(Leishmania mexicana)
BDBM50161334
PNG
(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-2-oxa-...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)N(C)C)C(=O)N1OCC2[C@H]1C(=O)CN2C(=O)c1ccccc1
Show InChI InChI=1S/C27H32N4O5/c1-17(2)14-21(28-25(33)18-10-12-20(13-11-18)29(3)4)27(35)31-24-22(16-36-31)30(15-23(24)32)26(34)19-8-6-5-7-9-19/h5-13,17,21-22,24H,14-16H2,1-4H3,(H,28,33)/t21-,22?,24-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
1.00E+3n/an/an/an/an/an/an/an/a



Amura Therapeutics Limited, Inc

Curated by ChEMBL


Assay Description
Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)


Citation and Details
More data for this
Ligand-Target Pair
Cysteine proteinase B


(Leishmania mexicana)
BDBM50161337
PNG
(N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrol...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)N(C)C)C(=O)N1CCC2[C@H]1C(=O)CN2C(=O)c1ccccc1
Show InChI InChI=1S/C28H34N4O4/c1-18(2)16-22(29-26(34)19-10-12-21(13-11-19)30(3)4)28(36)31-15-14-23-25(31)24(33)17-32(23)27(35)20-8-6-5-7-9-20/h5-13,18,22-23,25H,14-17H2,1-4H3,(H,29,34)/t22-,23?,25-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.17E+3n/an/an/an/an/an/an/an/a



Amura Therapeutics Limited, Inc

Curated by ChEMBL


Assay Description
Binding affinity against Leishmania mexicana cysteine peptidase B (CPB)


Citation and Details
More data for this
Ligand-Target Pair