BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 19 hits Enz. Inhib. hit(s) with Target = 'Cytochrome b-c1 complex subunit 7' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027963
PNG
(CHEMBL3360259)
Show SMILES Oc1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C18H15NO3S/c20-17-10-8-16(9-11-17)19-23(21,22)18-12-6-15(7-13-18)14-4-2-1-3-5-14/h1-13,19-20H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50028004
PNG
(CHEMBL3360267)
Show SMILES [K+].[O-]c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C18H15NO3S/c20-17-10-8-16(9-11-17)19-23(21,22)18-12-6-15(7-13-18)14-4-2-1-3-5-14/h1-13,19-20H/p-1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027960
PNG
(CHEMBL188279)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C16H19NO3S/c1-16(2,3)12-4-10-15(11-5-12)21(19,20)17-13-6-8-14(18)9-7-13/h4-11,17-18H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50028006
PNG
(CHEMBL186268)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccccc1O
Show InChI InChI=1S/C16H19NO3S/c1-16(2,3)12-8-10-13(11-9-12)21(19,20)17-14-6-4-5-7-15(14)18/h4-11,17-18H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50028005
PNG
(CHEMBL185823)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1cccc(O)c1
Show InChI InChI=1S/C16H19NO3S/c1-16(2,3)12-7-9-15(10-8-12)21(19,20)17-13-5-4-6-14(18)11-13/h4-11,17-18H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027965
PNG
(CHEMBL3360261)
Show SMILES Oc1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1Cl
Show InChI InChI=1S/C18H14ClNO3S/c19-17-12-15(8-11-18(17)21)20-24(22,23)16-9-6-14(7-10-16)13-4-2-1-3-5-13/h1-12,20-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027966
PNG
(CHEMBL3360262)
Show SMILES OC(=O)c1cc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)ccc1O
Show InChI InChI=1S/C19H15NO5S/c21-18-11-8-15(12-17(18)19(22)23)20-26(24,25)16-9-6-14(7-10-16)13-4-2-1-3-5-13/h1-12,20-21H,(H,22,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027967
PNG
(CHEMBL3360263)
Show SMILES Oc1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)c2ccccc12
Show InChI InChI=1S/C22H17NO3S/c24-22-15-14-21(19-8-4-5-9-20(19)22)23-27(25,26)18-12-10-17(11-13-18)16-6-2-1-3-7-16/h1-15,23-24H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027968
PNG
(CHEMBL3360264)
Show SMILES Oc1cccc2c(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)cccc12
Show InChI InChI=1S/C22H17NO3S/c24-22-11-5-8-19-20(22)9-4-10-21(19)23-27(25,26)18-14-12-17(13-15-18)16-6-2-1-3-7-16/h1-15,23-24H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027969
PNG
(CHEMBL3360268)
Show SMILES Oc1ccc(NS(=O)(=O)c2cc3SC(=O)c4cccc(c2)c34)c2ccccc12
Show InChI InChI=1S/C21H13NO4S2/c23-18-9-8-17(14-5-1-2-6-15(14)18)22-28(25,26)13-10-12-4-3-7-16-20(12)19(11-13)27-21(16)24/h1-11,22-23H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM60397
PNG
(MLS000115777 | N-(4-hydroxyphenyl)-8-quinolinesulf...)
Show SMILES Oc1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1
Show InChI InChI=1S/C15H12N2O3S/c18-13-8-6-12(7-9-13)17-21(19,20)14-5-1-3-11-4-2-10-16-15(11)14/h1-10,17-18H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50028007
PNG
(CHEMBL3360266)
Show SMILES Oc1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C16H13NO3S/c18-15-8-6-14(7-9-15)17-21(19,20)16-10-5-12-3-1-2-4-13(12)11-16/h1-11,17-18H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50028008
PNG
(CHEMBL3360265)
Show SMILES Oc1cccc2cccc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)c12
Show InChI InChI=1S/C22H17NO3S/c24-21-11-5-9-18-8-4-10-20(22(18)21)23-27(25,26)19-14-12-17(13-15-19)16-6-2-1-3-7-16/h1-15,23-24H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027964
PNG
(CHEMBL3360260)
Show SMILES Oc1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)cc1F
Show InChI InChI=1S/C18H14FNO3S/c19-17-12-15(8-11-18(17)21)20-24(22,23)16-9-6-14(7-10-16)13-4-2-1-3-5-13/h1-12,20-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027962
PNG
(CHEMBL3360258)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ncccc12
Show InChI InChI=1S/C19H20N2O3S/c1-19(2,3)13-6-8-14(9-7-13)25(23,24)21-16-10-11-17(22)18-15(16)5-4-12-20-18/h4-12,21-22H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027961
PNG
(CHEMBL3360257)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(O)c2ccccc12
Show InChI InChI=1S/C20H21NO3S/c1-20(2,3)14-8-10-15(11-9-14)25(23,24)21-18-12-13-19(22)17-7-5-4-6-16(17)18/h4-13,21-22H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50028009
PNG
(CHEMBL2322452)
Show SMILES Oc1ccc2cccc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)c2c1
Show InChI InChI=1S/C22H17NO3S/c24-19-12-9-18-7-4-8-22(21(18)15-19)23-27(25,26)20-13-10-17(11-14-20)16-5-2-1-3-6-16/h1-15,23-24H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027958
PNG
(CHEMBL3360255)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C13H13NO3S/c1-10-2-8-13(9-3-10)18(16,17)14-11-4-6-12(15)7-5-11/h2-9,14-15H,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027959
PNG
(CHEMBL3360256)
Show SMILES CCc1ccc(cc1)S(=O)(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C14H15NO3S/c1-2-11-3-9-14(10-4-11)19(17,18)15-12-5-7-13(16)8-6-12/h3-10,15-16H,2H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


Citation and Details
More data for this
Ligand-Target Pair