BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 10 hits Enz. Inhib. hit(s) with Target = 'Cytochrome c oxidase subunit 1' AND taxid = 9940   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50326826
PNG
(2-(4-acetamido)phenyl)-8-benzoyl-quinoline-4-carbo...)
Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(C(O)=O)c2cccc(C(=O)c3ccccc3)c2n1
Show InChI InChI=1S/C25H18N2O4/c1-15(28)26-18-12-10-16(11-13-18)22-14-21(25(30)31)19-8-5-9-20(23(19)27-22)24(29)17-6-3-2-4-7-17/h2-14H,1H3,(H,26,28)(H,30,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 9.20E+3n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50300870
PNG
(2-(4-(methylsulfonyl)phenyl)-quinoline-4-carboxyli...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2ccccc2n1
Show InChI InChI=1S/C17H13NO4S/c1-23(21,22)12-8-6-11(7-9-12)16-10-14(17(19)20)13-4-2-3-5-15(13)18-16/h2-10H,1H3,(H,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.34E+4n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50326828
PNG
(8-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2cccc(C(=O)c3ccccc3)c2n1
Show InChI InChI=1S/C24H17NO5S/c1-31(29,30)17-12-10-15(11-13-17)21-14-20(24(27)28)18-8-5-9-19(22(18)25-21)23(26)16-6-3-2-4-7-16/h2-14H,1H3,(H,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.59E+4n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50326827
PNG
(2-(4-acetamido)phenyl)-6-benzoyl-quinoline-4-carbo...)
Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(C(O)=O)c2cc(ccc2n1)C(=O)c1ccccc1
Show InChI InChI=1S/C25H18N2O4/c1-15(28)26-19-10-7-16(8-11-19)23-14-21(25(30)31)20-13-18(9-12-22(20)27-23)24(29)17-5-3-2-4-6-17/h2-14H,1H3,(H,26,28)(H,30,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.18E+4n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 2.43E+4n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50326829
PNG
(6-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2cc(ccc2n1)C(=O)c1ccccc1
Show InChI InChI=1S/C24H17NO5S/c1-31(29,30)18-10-7-15(8-11-18)22-14-20(24(27)28)19-13-17(9-12-21(19)25-22)23(26)16-5-3-2-4-6-16/h2-14H,1H3,(H,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.44E+4n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50326830
PNG
(2-(4-azido)phenyl)-8-benzoyl-quinoline-4-carboxyli...)
Show SMILES OC(=O)c1cc(nc2c(cccc12)C(=O)c1ccccc1)-c1ccc(cc1)N=[N+]=[N-]
Show InChI InChI=1S/C23H14N4O3/c24-27-26-16-11-9-14(10-12-16)20-13-19(23(29)30)17-7-4-8-18(21(17)25-20)22(28)15-5-2-1-3-6-15/h1-13H,(H,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6.56E+4n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM13063
PNG
(4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sul...)
Show SMILES Cc1onc(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1
Show InChI InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 9.62E+4n/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Inhibition of ovine cyclooxygenase 1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50326831
PNG
(2-(4-azido)phenyl)-6-benzoyl-quinoline-4-carboxyli...)
Show SMILES OC(=O)c1cc(nc2ccc(cc12)C(=O)c1ccccc1)-c1ccc(cc1)N=[N+]=[N-]
Show InChI InChI=1S/C23H14N4O3/c24-27-26-17-9-6-14(7-10-17)21-13-19(23(29)30)18-12-16(8-11-20(18)25-21)22(28)15-4-2-1-3-5-15/h1-13H,(H,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Shahid Beheshti University of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of sheep COX1


Citation and Details
More data for this
Ligand-Target Pair
Cytochrome c oxidase subunit 1


(Ovis aries)
BDBM50229774
PNG
(CHEMBL254418 | N-Hydroxy-4-(5-methyl-3-phenylisoxa...)
Show SMILES Cc1onc(c1-c1ccc(cc1)S(=O)(=O)NO)-c1ccccc1
Show InChI InChI=1S/C16H14N2O4S/c1-11-15(16(17-22-11)13-5-3-2-4-6-13)12-7-9-14(10-8-12)23(20,21)18-19/h2-10,18-19H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.57E+5n/an/an/an/an/an/a



Gedeon Richter Plc

Curated by ChEMBL


Assay Description
Inhibition of ovine cyclooxygenase 1


Citation and Details
More data for this
Ligand-Target Pair