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Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Cytohesin-2' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytohesin-2


(Homo sapiens)
BDBM50441975
PNG
(CHEMBL2440216)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C14H14N2O5S/c1-9-7-12(17)8-10(2)14(9)15-22(20,21)13-5-3-11(4-6-13)16(18)19/h3-8,15,17H,1-2H3
PDB
MMDB

KEGG

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B.MOAD
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PC sid
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Article
PubMed
5.40E+5n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441972
PNG
(CHEMBL2440207)
Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc1ccc(O)cc1C
Show InChI InChI=1S/C16H19NO3S/c1-10-7-12(3)16(13(4)8-10)21(19,20)17-15-6-5-14(18)9-11(15)2/h5-9,17-18H,1-4H3
PDB
MMDB

KEGG

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CHEMBL
PC cid
PC sid
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PubMed
9.80E+5n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441973
PNG
(CHEMBL2440218)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3
PDB
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KEGG

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CHEMBL
MMDB
PC cid
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PDB
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PDB
Article
PubMed
1.61E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cytohesin-2


(Homo sapiens)
BDBM50441976
PNG
(CHEMBL2440213)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO3S/c1-10-4-6-14(7-5-10)20(18,19)16-15-11(2)8-13(17)9-12(15)3/h4-9,16-17H,1-3H3
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KEGG

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CHEMBL
PC cid
PC sid
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PubMed
1.91E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
PDB
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KEGG

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CHEMBL
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PDB
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PDB
Article
PubMed
3.72E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cytohesin-2


(Homo sapiens)
BDBM50441974
PNG
(CHEMBL236358)
Show SMILES Cc1cc(NS(=O)(=O)c2ccccc2)cc(C)c1O
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(9-11(2)14(10)16)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
PDB
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KEGG

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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
5.12E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

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PDB
Article
PubMed
n/an/an/a 5.00E+5n/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip after 15 mins by 1H 1D-NMR-700 MHz spectra analysis


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)