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Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with Target = 'D-Amino Acid Oxidase (DAAO)' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431086
PNG
(CHEMBL2338800 | US9212147, 212 | US9290456, 2)
Show SMILES Oc1cc(CCc2ccc(F)cc2)n[nH]c1=O
Show InChI InChI=1S/C12H11FN2O2/c13-9-4-1-8(2-5-9)3-6-10-7-11(16)12(17)15-14-10/h1-2,4-5,7H,3,6H2,(H,14,16)(H,15,17)
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n/an/a 2.20n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431066
PNG
(CHEMBL2338798 | US9212147, 17 | US9290456, 11)
Show SMILES Oc1cc(CCc2cccc(c2)C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)9-3-1-2-8(6-9)4-5-10-7-11(19)12(20)18-17-10/h1-3,6-7H,4-5H2,(H,17,19)(H,18,20)
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n/an/a 2.20n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431074
PNG
(CHEMBL2338790 | US9212147, 254 | US9290456, 27)
Show SMILES Oc1cc(CCc2ccc(Cl)cc2)n[nH]c1=O
Show InChI InChI=1S/C12H11ClN2O2/c13-9-4-1-8(2-5-9)3-6-10-7-11(16)12(17)15-14-10/h1-2,4-5,7H,3,6H2,(H,14,16)(H,15,17)
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n/an/a 2.40n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431067
PNG
(CHEMBL2338797 | US9212147, 18 | US9290456, 6)
Show SMILES Oc1cc(CCc2cccc(F)c2)n[nH]c1=O
Show InChI InChI=1S/C12H11FN2O2/c13-9-3-1-2-8(6-9)4-5-10-7-11(16)12(17)15-14-10/h1-3,6-7H,4-5H2,(H,14,16)(H,15,17)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431077
PNG
(CHEMBL2338787 | US9212147, 48 | US9290456, 56)
Show SMILES CC(c1ccccc1)c1cc(O)c(=O)[nH]n1
Show InChI InChI=1S/C12H12N2O2/c1-8(9-5-3-2-4-6-9)10-7-11(15)12(16)14-13-10/h2-8H,1H3,(H,13,15)(H,14,16)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431084
PNG
(CHEMBL2338802)
Show SMILES COc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1
Show InChI InChI=1S/C13H14N2O3/c1-18-11-6-3-9(4-7-11)2-5-10-8-12(16)13(17)15-14-10/h3-4,6-8H,2,5H2,1H3,(H,14,16)(H,15,17)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31173
PNG
(naphthyridinone analog., 27)
Show SMILES Oc1cc2c(Cl)c(F)cnc2[nH]c1=O
Show InChI InChI=1S/C8H4ClFN2O2/c9-6-3-1-5(13)8(14)12-7(3)11-2-4(6)10/h1-2,13H,(H,11,12,14)
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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431078
PNG
(CHEMBL2338786 | US9290456, 1)
Show SMILES Oc1cc(CCc2ccccc2)n[nH]c1=O
Show InChI InChI=1S/C12H12N2O2/c15-11-8-10(13-14-12(11)16)7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H,13,15)(H,14,16)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431069
PNG
(CHEMBL2338795 | US9212147, 27 | US9290456, 7)
Show SMILES Oc1cc(CCc2ccccc2F)n[nH]c1=O
Show InChI InChI=1S/C12H11FN2O2/c13-10-4-2-1-3-8(10)5-6-9-7-11(16)12(17)15-14-9/h1-4,7H,5-6H2,(H,14,16)(H,15,17)
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n/an/a 4.90n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431085
PNG
(CHEMBL2338801 | US9212147, 12 | US9290456, 36)
Show SMILES Oc1cc(CCc2ccc(cc2)C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)9-4-1-8(2-5-9)3-6-10-7-11(19)12(20)18-17-10/h1-2,4-5,7H,3,6H2,(H,17,19)(H,18,20)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431065
PNG
(CHEMBL2338799)
Show SMILES COc1cccc(CCc2cc(O)c(=O)[nH]n2)c1
Show InChI InChI=1S/C13H14N2O3/c1-18-11-4-2-3-9(7-11)5-6-10-8-12(16)13(17)15-14-10/h2-4,7-8H,5-6H2,1H3,(H,14,16)(H,15,17)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431070
PNG
(CHEMBL2338794)
Show SMILES Oc1cc(COc2ccccc2)n[nH]c1=O
Show InChI InChI=1S/C11H10N2O3/c14-10-6-8(12-13-11(10)15)7-16-9-4-2-1-3-5-9/h1-6H,7H2,(H,12,14)(H,13,15)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431075
PNG
(CHEMBL2338789 | US9290456, 13)
Show SMILES Oc1cc(CCC2CCCCC2)n[nH]c1=O
Show InChI InChI=1S/C12H18N2O2/c15-11-8-10(13-14-12(11)16)7-6-9-4-2-1-3-5-9/h8-9H,1-7H2,(H,13,15)(H,14,16)
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n/an/a 8.20n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431083
PNG
(CHEMBL2338803 | US9212147, 24 | US9290456, 8)
Show SMILES Oc1cc(CCc2cc(F)cc(F)c2)n[nH]c1=O
Show InChI InChI=1S/C12H10F2N2O2/c13-8-3-7(4-9(14)5-8)1-2-10-6-11(17)12(18)16-15-10/h3-6H,1-2H2,(H,15,17)(H,16,18)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431081
PNG
(CHEMBL2338805)
Show SMILES COc1cc(CCc2cc(O)c(=O)[nH]n2)cc(OC)c1
Show InChI InChI=1S/C14H16N2O4/c1-19-11-5-9(6-12(8-11)20-2)3-4-10-7-13(17)14(18)16-15-10/h5-8H,3-4H2,1-2H3,(H,15,17)(H,16,18)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31156
PNG
(3-hydroxyquinolin-2(1H)-one, 10)
Show SMILES Oc1cc2c(Cl)cccc2[nH]c1=O
Show InChI InChI=1S/C9H6ClNO2/c10-6-2-1-3-7-5(6)4-8(12)9(13)11-7/h1-4,12H,(H,11,13)
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n/an/a 40n/an/an/an/a8.522



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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431068
PNG
(CHEMBL2338796 | US9212147, 30 | US9290456, 29)
Show SMILES Oc1cc(CCc2ccccc2C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C13H11F3N2O2/c14-13(15,16)10-4-2-1-3-8(10)5-6-9-7-11(19)12(20)18-17-9/h1-4,7H,5-6H2,(H,17,19)(H,18,20)
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Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31172
PNG
(3-hydroxyquinolin-2(1H)-one, 26)
Show SMILES Oc1cc2c(Cl)c(F)ccc2[nH]c1=O
Show InChI InChI=1S/C9H5ClFNO2/c10-8-4-3-7(13)9(14)12-6(4)2-1-5(8)11/h1-3,13H,(H,12,14)
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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31149
PNG
(3-hydroxyquinolin-2(1H)-one, 3)
Show SMILES Oc1cc2cccc(F)c2[nH]c1=O
Show InChI InChI=1S/C9H6FNO2/c10-6-3-1-2-5-4-7(12)9(13)11-8(5)6/h1-4,12H,(H,11,13)
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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31152
PNG
(3-hydroxyquinolin-2(1H)-one, 6)
Show SMILES Oc1cc2c(F)cccc2[nH]c1=O
Show InChI InChI=1S/C9H6FNO2/c10-6-2-1-3-7-5(6)4-8(12)9(13)11-7/h1-4,12H,(H,11,13)
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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31164
PNG
(naphthyridinone analog.,18)
Show SMILES Oc1cc2cccnc2[nH]c1=O
Show InChI InChI=1S/C8H6N2O2/c11-6-4-5-2-1-3-9-7(5)10-8(6)12/h1-4,11H,(H,9,10,12)
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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31148
PNG
(3-hydroxyquinolin-2(1H)-one, 2)
Show SMILES Oc1cc2ccccc2[nH]c1=O
Show InChI InChI=1S/C9H7NO2/c11-8-5-6-3-1-2-4-7(6)10-9(8)12/h1-5,11H,(H,10,12)
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n/an/a 215n/an/an/an/a8.522



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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31151
PNG
(3-hydroxyquinolin-2(1H)-one, 5)
Show SMILES Oc1cc2cc(F)ccc2[nH]c1=O
Show InChI InChI=1S/C9H6FNO2/c10-6-1-2-7-5(3-6)4-8(12)9(13)11-7/h1-4,12H,(H,11,13)
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n/an/a 308n/an/an/an/a8.522



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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31147
PNG
(4H-furo[3,2-b]pyrrole-5-carboxylic acid | 5-carbox...)
Show SMILES OC(=O)c1cc2occc2[nH]1
Show InChI InChI=1S/C7H5NO3/c9-7(10)5-3-6-4(8-5)1-2-11-6/h1-3,8H,(H,9,10)
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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431073
PNG
(CHEMBL2338791)
Show SMILES Oc1cc(C=Cc2ccc(Cl)cc2)n[nH]c1=O
Show InChI InChI=1S/C12H9ClN2O2/c13-9-4-1-8(2-5-9)3-6-10-7-11(16)12(17)15-14-10/h1-7H,(H,14,16)(H,15,17)
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n/an/a 470n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
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Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431072
PNG
(CHEMBL2338792)
Show SMILES Oc1cc(n[nH]c1=O)C1CCCCC1
Show InChI InChI=1S/C10H14N2O2/c13-9-6-8(11-12-10(9)14)7-4-2-1-3-5-7/h6-7H,1-5H2,(H,11,13)(H,12,14)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431071
PNG
(CHEMBL2338793)
Show SMILES CC(C)(C)CCc1cc(O)c(=O)[nH]n1
Show InChI InChI=1S/C10H16N2O2/c1-10(2,3)5-4-7-6-8(13)9(14)12-11-7/h6H,4-5H2,1-3H3,(H,11,13)(H,12,14)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431076
PNG
(CHEMBL2338788 | US9212147, 53)
Show SMILES Oc1cc(CCCc2ccccc2)n[nH]c1=O
Show InChI InChI=1S/C13H14N2O2/c16-12-9-11(14-15-13(12)17)8-4-7-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H,14,16)(H,15,17)
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n/an/a 1.22E+3n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31150
PNG
(3-hydroxyquinolin-2(1H)-one, 4)
Show SMILES Oc1cc2ccc(F)cc2[nH]c1=O
Show InChI InChI=1S/C9H6FNO2/c10-6-2-1-5-3-8(12)9(13)11-7(5)4-6/h1-4,12H,(H,11,13)
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n/an/a 1.45E+3n/an/an/an/a8.522



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50431082
PNG
(CHEMBL2338804 | US9212147, 19 | US9290456, 61)
Show SMILES Oc1cc(CCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)n[nH]c1=O
Show InChI InChI=1S/C14H10F6N2O2/c15-13(16,17)8-3-7(4-9(5-8)14(18,19)20)1-2-10-6-11(23)12(24)22-21-10/h3-6H,1-2H2,(H,21,23)(H,22,24)
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n/an/a 1.90E+3n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31165
PNG
(naphthyridinone analog.,19)
Show SMILES Oc1cc2cnccc2[nH]c1=O
Show InChI InChI=1S/C8H6N2O2/c11-7-3-5-4-9-2-1-6(5)10-8(7)12/h1-4,11H,(H,10,12)
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n/an/a 3.08E+3n/an/an/an/a8.522



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31161
PNG
(3-hydroxyquinolin-2(1H)-one, 15)
Show SMILES CCc1cccc2[nH]c(=O)c(O)cc12
Show InChI InChI=1S/C11H11NO2/c1-2-7-4-3-5-9-8(7)6-10(13)11(14)12-9/h3-6,13H,2H2,1H3,(H,12,14)
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n/an/a 3.67E+3n/an/an/an/a8.522



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31160
PNG
(3-hydroxyquinolin-2(1H)-one, 14)
Show SMILES Cc1cccc2[nH]c(=O)c(O)cc12
Show InChI InChI=1S/C10H9NO2/c1-6-3-2-4-8-7(6)5-9(12)10(13)11-8/h2-5,12H,1H3,(H,11,13)
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n/an/a 8.47E+3n/an/an/an/a8.522



Pfizer



Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM31153
PNG
(3-hydroxyquinolin-2(1H)-one, 7)
Show SMILES Oc1cc2cccc(Cl)c2[nH]c1=O
Show InChI InChI=1S/C9H6ClNO2/c10-6-3-1-2-5-4-7(12)9(13)11-8(5)6/h1-4,12H,(H,11,13)
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n/an/a 8.72E+3n/an/an/an/a8.522



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Assay Description
Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50427008
PNG
(CHEMBL2326864)
Show SMILES CC(=O)Nc1nc(CCc2ccc(cc2)N=C(N)N)cs1
Show InChI InChI=1S/C14H17N5OS/c1-9(20)17-14-19-12(8-21-14)7-4-10-2-5-11(6-3-10)18-13(15)16/h2-3,5-6,8H,4,7H2,1H3,(H4,15,16,18)(H,17,19,20)
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n/an/a 7.50E+4n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat liver DAO using putrescine as substrate after 1 hr by fluorometric assay


Citation and Details
More data for this
Ligand-Target Pair
D-Amino Acid Oxidase (DAAO)


(Rattus norvegicus (rat))
BDBM50433257
PNG
(CHEMBL2376160 | CHEMBL2376161)
Show SMILES CC(=O)Nc1nc(CCc2ccc(cc2)N=C(N)N)c(Cc2ccc(cc2)S(C)(=O)=O)s1
Show InChI InChI=1S/C22H25N5O3S2/c1-14(28)25-22-27-19(12-7-15-3-8-17(9-4-15)26-21(23)24)20(31-22)13-16-5-10-18(11-6-16)32(2,29)30/h3-6,8-11H,7,12-13H2,1-2H3,(H4,23,24,26)(H,25,27,28)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat DAO using [14C]-putrescine as substrate after 1 hr by scintillation counting analysis


Citation and Details
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Ligand-Target Pair