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Found 9 hits Enz. Inhib. hit(s) with Target = 'DNA nucleotidylexotransferase' AND taxid = 9913   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50356642
PNG
(CHEMBL1917196)
Show SMILES CCCCCCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12
Show InChI InChI=1S/C22H28O4/c1-2-3-4-5-6-7-8-9-10-14-21(25)26-20-13-11-12-17-18(23)15-16-19(24)22(17)20/h11-13,15-16H,2-10,14H2,1H3
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n/an/a 8.40E+3n/an/an/an/an/an/a



Kyoto Prefectural University

Curated by ChEMBL


Assay Description
Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 mins


Bioorg Med Chem 19: 5803-12 (2011)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50356643
PNG
(CHEMBL1917198)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12
Show InChI InChI=1S/C28H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-27(31)32-26-19-17-18-23-24(29)21-22-25(30)28(23)26/h9-10,17-19,21-22H,2-8,11-16,20H2,1H3/b10-9-
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n/an/a 1.19E+4n/an/an/an/an/an/a



Kyoto Prefectural University

Curated by ChEMBL


Assay Description
Inhibition of calf thymus TdT using oligo(dT)18 (3'-OH) and dTTP as the DNA template-primer and nucleotide substrate after 60 mins


Bioorg Med Chem 19: 5803-12 (2011)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50448688
PNG
(PECILOCIN | Pecilocin | Variotin)
Show SMILES CCCC[C@@H](O)\C=C(/C)\C=C\C=C\C(=O)N1CCCC1=O
Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5-6,8,10,13,15,19H,3-4,7,9,11-12H2,1-2H3/b8-5+,10-6+,14-13+/t15-/m1/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of calf thymus TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins


Bioorg Med Chem 22: 1070-6 (2014)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50448691
PNG
(CHEMBL3127729)
Show SMILES C\C(\C=C\CCC(=O)N1CCCC1=O)=C/C1CCCCO1
Show InChI InChI=1S/C17H25NO3/c1-14(13-15-8-4-5-12-21-15)7-2-3-9-16(19)18-11-6-10-17(18)20/h2,7,13,15H,3-6,8-12H2,1H3/b7-2+,14-13+
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n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of calf thymus TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins


Bioorg Med Chem 22: 1070-6 (2014)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50448690
PNG
(CHEMBL3127728)
Show SMILES CCCCC(=O)C=C(C)C=CCCC(=O)N1CCCC1=O
Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5,8,13H,3-4,6-7,9-12H2,1-2H3
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n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of calf thymus TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins


Bioorg Med Chem 22: 1070-6 (2014)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50448689
PNG
(CHEMBL3127730)
Show SMILES CCCC[C@@H](O)\C=C(/C)\C=C\C=C/C(=O)N1CCCC1=O
Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5-6,8,10,13,15,19H,3-4,7,9,11-12H2,1-2H3/b8-5+,10-6-,14-13+/t15-/m1/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of calf thymus TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins


Bioorg Med Chem 22: 1070-6 (2014)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50379293
PNG
(CHEMBL2011648)
Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1
Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins


J Nat Prod 75: 135-41 (2012)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50379294
PNG
(CHEMBL2011647)
Show SMILES Cc1cc(O)cc(O)c1C(=O)O[C@H]1[C@@H]2COC(\C=C\CO)=CC2=CC(=O)[C@@]1(C)O
Show InChI InChI=1S/C21H22O8/c1-11-6-13(23)9-16(24)18(11)20(26)29-19-15-10-28-14(4-3-5-22)7-12(15)8-17(25)21(19,2)27/h3-4,6-9,15,19,22-24,27H,5,10H2,1-2H3/b4-3+/t15-,19+,21-/m1/s1
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n/an/a>2.00E+5n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins


J Nat Prod 75: 135-41 (2012)

More data for this
Ligand-Target Pair
DNA nucleotidylexotransferase


(Bos taurus)
BDBM50379292
PNG
(CHEMBL2011646)
Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(OC(=O)c3c(C)cc(O)cc3O)[C@@H](O)[C@@H]2CO1
Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,19(25)15(12)10-27-14)28-20(26)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,25H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1
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PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 mins


J Nat Prod 75: 135-41 (2012)

More data for this
Ligand-Target Pair