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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'DNA polymerase I' AND taxid = 83333   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase I


(Escherichia coli (strain K12))
BDBM50154439
PNG
(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccc(O)c1
Show InChI InChI=1S/C11H8N2O5/c14-6-3-1-2-5(4-6)9-12-7(11(17)18)8(15)10(16)13-9/h1-4,14-15H,(H,17,18)(H,12,13,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Italy. Vinc

Curated by ChEMBL


Assay Description
Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymerase


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase I


(Escherichia coli (strain K12))
BDBM50154444
PNG
(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccc(OCc2ccccc2)c1
Show InChI InChI=1S/C18H14N2O5/c21-15-14(18(23)24)19-16(20-17(15)22)12-7-4-8-13(9-12)25-10-11-5-2-1-3-6-11/h1-9,21H,10H2,(H,23,24)(H,19,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Italy. Vinc

Curated by ChEMBL


Assay Description
Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymerase


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase I


(Escherichia coli (strain K12))
BDBM33414
PNG
(CHEMBL440562 | pyrimidinol carboxylic acid, 6)
Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccccc1
Show InChI InChI=1S/C11H8N2O4/c14-8-7(11(16)17)12-9(13-10(8)15)6-4-2-1-3-5-6/h1-5,14H,(H,16,17)(H,12,13,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Italy. Vinc

Curated by ChEMBL


Assay Description
Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymerase


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase I


(Escherichia coli (strain K12))
BDBM50154442
PNG
(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C11H7ClN2O4/c12-6-3-1-5(2-4-6)9-13-7(11(17)18)8(15)10(16)14-9/h1-4,15H,(H,17,18)(H,13,14,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Italy. Vinc

Curated by ChEMBL


Assay Description
Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymerase


Citation and Details
More data for this
Ligand-Target Pair