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Found 4 hits Enz. Inhib. hit(s) with Target = 'DNA polymerase alpha catalytic subunit' AND taxid = 7227   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase alpha catalytic subunit


(Drosophila melanogaster)
BDBM50448691
PNG
(CHEMBL3127729)
Show SMILES C\C(\C=C\CCC(=O)N1CCCC1=O)=C/C1CCCCO1
Show InChI InChI=1S/C17H25NO3/c1-14(13-15-8-4-5-12-21-15)7-2-3-9-16(19)18-11-6-10-17(18)20/h2,7,13,15H,3-6,8-12H2,1H3/b7-2+,14-13+
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UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
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Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of fruit fly DNA polymerase alpha assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase alpha catalytic subunit


(Drosophila melanogaster)
BDBM50448688
PNG
(PECILOCIN | Pecilocin | Variotin)
Show SMILES CCCC[C@@H](O)\C=C(/C)\C=C\C=C\C(=O)N1CCCC1=O
Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5-6,8,10,13,15,19H,3-4,7,9,11-12H2,1-2H3/b8-5+,10-6+,14-13+/t15-/m1/s1
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UniProtKB/SwissProt

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AffyNet 
KEGG
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of fruit fly DNA polymerase alpha assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase alpha catalytic subunit


(Drosophila melanogaster)
BDBM50448689
PNG
(CHEMBL3127730)
Show SMILES CCCC[C@@H](O)\C=C(/C)\C=C\C=C/C(=O)N1CCCC1=O
Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5-6,8,10,13,15,19H,3-4,7,9,11-12H2,1-2H3/b8-5+,10-6-,14-13+/t15-/m1/s1
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UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of fruit fly DNA polymerase alpha assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase alpha catalytic subunit


(Drosophila melanogaster)
BDBM50448690
PNG
(CHEMBL3127728)
Show SMILES CCCCC(=O)C=C(C)C=CCCC(=O)N1CCCC1=O
Show InChI InChI=1S/C17H25NO3/c1-3-4-9-15(19)13-14(2)8-5-6-10-16(20)18-12-7-11-17(18)21/h5,8,13H,3-4,6-7,9-12H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Kobe Gakuin University

Curated by ChEMBL


Assay Description
Inhibition of fruit fly DNA polymerase alpha assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins


Citation and Details
More data for this
Ligand-Target Pair