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Found 7 hits Enz. Inhib. hit(s) with Target = 'DNA polymerase iota' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase iota


(Mus musculus)
BDBM50356642
PNG
(CHEMBL1917196)
Show SMILES CCCCCCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12
Show InChI InChI=1S/C22H28O4/c1-2-3-4-5-6-7-8-9-10-14-21(25)26-20-13-11-12-17-18(23)15-16-19(24)22(17)20/h11-13,15-16H,2-10,14H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.10E+3n/an/an/an/an/an/a



Kyoto Prefectural University

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase iota


(Mus musculus)
BDBM50356643
PNG
(CHEMBL1917198)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12
Show InChI InChI=1S/C28H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-27(31)32-26-19-17-18-23-24(29)21-22-25(30)28(23)26/h9-10,17-19,21-22H,2-8,11-16,20H2,1H3/b10-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.70E+3n/an/an/an/an/an/a



Kyoto Prefectural University

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His6-tagged mouse DNA polymerase iota using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleot...


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase iota


(Mus musculus)
BDBM50276865
PNG
(4-[(2E)-but-2-enoyl]-2-[(1E,3E)-5-hydroxyhexa-1,3-...)
Show SMILES COC1=C(C(=O)C=CC)C(=O)C(C)(O1)\C=C\C=C\C(C)O
Show InChI InChI=1S/C16H20O5/c1-5-8-12(18)13-14(19)16(3,21-15(13)20-4)10-7-6-9-11(2)17/h5-11,17H,1-4H3/b8-5?,9-6+,10-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.98E+4n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of mouse DNA polymerase iota


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase iota


(Mus musculus)
BDBM50276936
PNG
(4-(3-hydroxybutanoyl)-2-[(1E,3E)-5-hydroxyhexa-1,3...)
Show SMILES COC1=C(C(=O)CC(C)O)C(=O)C(C)(O1)\C=C\C=C\C(C)O
Show InChI InChI=1S/C16H22O6/c1-10(17)7-5-6-8-16(3)14(20)13(15(21-4)22-16)12(19)9-11(2)18/h5-8,10-11,17-18H,9H2,1-4H3/b7-5+,8-6+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.25E+4n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of mouse DNA polymerase iota


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase iota


(Mus musculus)
BDBM50379292
PNG
(CHEMBL2011646)
Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(OC(=O)c3c(C)cc(O)cc3O)[C@@H](O)[C@@H]2CO1
Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,19(25)15(12)10-27-14)28-20(26)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,25H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.02E+4n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase iota


(Mus musculus)
BDBM50379293
PNG
(CHEMBL2011648)
Show SMILES C\C=C\C1=CC2=CC(=O)[C@@](C)(O)[C@@H](OC(=O)c3c(C)cc(O)cc3O)[C@@H]2CO1
Show InChI InChI=1S/C21H22O7/c1-4-5-14-7-12-8-17(24)21(3,26)19(15(12)10-27-14)28-20(25)18-11(2)6-13(22)9-16(18)23/h4-9,15,19,22-23,26H,10H2,1-3H3/b5-4+/t15-,19+,21-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6.38E+4n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...


Citation and Details
More data for this
Ligand-Target Pair
DNA polymerase iota


(Mus musculus)
BDBM50379294
PNG
(CHEMBL2011647)
Show SMILES Cc1cc(O)cc(O)c1C(=O)O[C@H]1[C@@H]2COC(\C=C\CO)=CC2=CC(=O)[C@@]1(C)O
Show InChI InChI=1S/C21H22O8/c1-11-6-13(23)9-16(24)18(11)20(26)29-19-15-10-28-14(4-3-5-22)7-12(15)8-17(25)21(19,2)27/h3-4,6-9,15,19,22-24,27H,5,10H2,1-2H3/b4-3+/t15-,19+,21-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 9.10E+4n/an/an/an/an/an/a



Science University of Tokyo

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...


Citation and Details
More data for this
Ligand-Target Pair