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Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'DNA-damage-inducible protein G (DinG)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM213233
PNG
(Telomestatin (TMS))
Show SMILES Cc1oc2nc1-c1nc(c(C)o1)-c1nc(co1)-c1nc(co1)-c1nc(co1)-c1nc(co1)-c1nc(co1)C1=NC2CS1
Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3
PDB

UniProtKB/SwissProt

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KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM213233
PNG
(Telomestatin (TMS))
Show SMILES Cc1oc2nc1-c1nc(c(C)o1)-c1nc(co1)-c1nc(co1)-c1nc(co1)-c1nc(co1)-c1nc(co1)C1=NC2CS1
Show InChI InChI=1S/C26H14N8O7S/c1-9-17-24-30-14(6-39-24)21-28-12(4-37-21)19-27-11(3-35-19)20-29-13(5-36-20)22-31-15(7-38-22)26-32-16(8-42-26)23-33-18(10(2)40-23)25(34-17)41-9/h3-7,16H,8H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
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KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.5n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM50376748
PNG
(CHEMBL259739 | Phen-DC3)
Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12
Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2
PDB

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
MMDB
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 50n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM213234
PNG
(Phen-DC6)
Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12
Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 55n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM213234
PNG
(Phen-DC6)
Show SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12
Show InChI InChI=1S/C34H24N6O2/c1-39-17-3-5-23-19-25(11-15-29(23)39)35-33(41)27-13-9-21-7-8-22-10-14-28(38-32(22)31(21)37-27)34(42)36-26-12-16-30-24(20-26)6-4-18-40(30)2/h3-20H,1-2H3/p+2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 60n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM50376748
PNG
(CHEMBL259739 | Phen-DC3)
Show SMILES C[n+]1cc(NC(=O)c2ccc3ccc4ccc(nc4c3n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12
Show InChI InChI=1S/C34H24N6O2/c1-39-19-25(17-23-7-3-5-9-29(23)39)35-33(41)27-15-13-21-11-12-22-14-16-28(38-32(22)31(21)37-27)34(42)36-26-18-24-8-4-6-10-30(24)40(2)20-26/h3-20H,1-2H3/p+2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 130n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM50107609
PNG
(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2
Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair
DNA-damage-inducible protein G (DinG)


(Escherichia coli (Enterobacteria))
BDBM50107609
PNG
(5,10,15,20-tetra(1-methyl-4-pyridyl)-porphyrin | C...)
Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2
Show InChI InChI=1S/C44H37N8/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31/h5-28H,1-4H3,(H,45,46,47,48)/q+3/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/a8.0n/a



National Institutes of Health, National Institutes of Health Biomedical Research Center



Assay Description
Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...


J Biol Chem 288: 28217-29 (2013)


Article DOI: 10.1074/jbc.M113.496463
BindingDB Entry DOI: 10.7270/Q2FT8JVS
More data for this
Ligand-Target Pair