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Found 3 hits Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase (DNAPK)' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-dependent protein kinase (DNAPK)


(Mus musculus (Mouse))
BDBM50398035
PNG
(CHEMBL2181111)
Show SMILES Oc1cc(N2CCOCC2)c(-c2ccccc2)c2oc(cc(=O)c12)-c1ccccc1
Show InChI InChI=1S/C25H21NO4/c27-20-15-19(26-11-13-29-14-12-26)23(18-9-5-2-6-10-18)25-24(20)21(28)16-22(30-25)17-7-3-1-4-8-17/h1-10,15-16,27H,11-14H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 34n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of DNA-PK in C57BL6 mouse endothelial cells


Citation and Details
More data for this
Ligand-Target Pair
DNA-dependent protein kinase (DNAPK)


(Mus musculus (Mouse))
BDBM50398036
PNG
(CHEMBL1317546)
Show SMILES CC(=O)c1ccc(cc1O)N1CCOCC1
Show InChI InChI=1S/C12H15NO3/c1-9(14)11-3-2-10(8-12(11)15)13-4-6-16-7-5-13/h2-3,8,15H,4-7H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of DNA-PK in C57BL6 mouse endothelial cells


Citation and Details
More data for this
Ligand-Target Pair
DNA-dependent protein kinase (DNAPK)


(Mus musculus (Mouse))
BDBM217352
PNG
(GS-9820)
Show SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2c(=O)n1-c1ccccc1
Show InChI InChI=1/C21H16FN7O/c1-12(27-19-17-18(24-10-23-17)25-11-26-19)20-28-16-8-7-13(22)9-15(16)21(30)29(20)14-5-3-2-4-6-14/h2-12H,1H3,(H2,23,24,25,26,27)/t12-/s2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.87E+4n/an/an/an/an/an/a



Western University



Assay Description
Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...


Citation and Details
More data for this
Ligand-Target Pair