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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase catalytic subunit' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-dependent protein kinase catalytic subunit


(Mus musculus)
BDBM50398035
PNG
(CHEMBL2181111)
Show SMILES Oc1cc(N2CCOCC2)c(-c2ccccc2)c2oc(cc(=O)c12)-c1ccccc1
Show InChI InChI=1S/C25H21NO4/c27-20-15-19(26-11-13-29-14-12-26)23(18-9-5-2-6-10-18)25-24(20)21(28)16-22(30-25)17-7-3-1-4-8-17/h1-10,15-16,27H,11-14H2
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 34n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of DNA-PK in C57BL6 mouse endothelial cells


Citation and Details
More data for this
Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit


(Mus musculus)
BDBM50398036
PNG
(CHEMBL1317546)
Show SMILES CC(=O)c1ccc(cc1O)N1CCOCC1
Show InChI InChI=1S/C12H15NO3/c1-9(14)11-3-2-10(8-12(11)15)13-4-6-16-7-5-13/h2-3,8,15H,4-7H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of DNA-PK in C57BL6 mouse endothelial cells


Citation and Details
More data for this
Ligand-Target Pair