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Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'DOPA decarboxylase' AND taxid = 9823   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DOPA decarboxylase


(Sus scrofa)
BDBM50005740
PNG
((+)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropa necarb...)
Show SMILES NC1(CC1c1cccc(O)c1)C(O)=O
Show InChI InChI=1S/C10H11NO3/c11-10(9(13)14)5-8(10)6-2-1-3-7(12)4-6/h1-4,8,12H,5,11H2,(H,13,14)
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2.20E+4n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase (Dopamine decarboxylase)


J Med Chem 35: 1410-7 (1992)

More data for this
Ligand-Target Pair
DOPA decarboxylase


(Sus scrofa)
BDBM50005743
PNG
((-)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropanecarbo...)
Show SMILES N[C@]1(C[C@H]1c1cccc(O)c1)C(O)=O
Show InChI InChI=1S/C10H11NO3/c11-10(9(13)14)5-8(10)6-2-1-3-7(12)4-6/h1-4,8,12H,5,11H2,(H,13,14)/t8-,10-/m0/s1
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4.90E+4n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase(Dopa decarboxylase)


J Med Chem 35: 1410-7 (1992)

More data for this
Ligand-Target Pair
DOPA decarboxylase


(Sus scrofa)
BDBM50005741
PNG
((+)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropanecarbo...)
Show SMILES N[C@@]1(C[C@@H]1c1cccc(O)c1)C(O)=O
Show InChI InChI=1S/C10H11NO3/c11-10(9(13)14)5-8(10)6-2-1-3-7(12)4-6/h1-4,8,12H,5,11H2,(H,13,14)/t8-,10-/m1/s1
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PubMed
3.30E+5n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase (Dopa decarboxylase)


J Med Chem 35: 1410-7 (1992)

More data for this
Ligand-Target Pair
DOPA decarboxylase


(Sus scrofa)
BDBM50005740
PNG
((+)-1-Amino-2-(3-hydroxy-phenyl)-cyclopropa necarb...)
Show SMILES NC1(CC1c1cccc(O)c1)C(O)=O
Show InChI InChI=1S/C10H11NO3/c11-10(9(13)14)5-8(10)6-2-1-3-7(12)4-6/h1-4,8,12H,5,11H2,(H,13,14)
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PubMed
6.30E+5n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase(Dopa decarboxylase)


J Med Chem 35: 1410-7 (1992)

More data for this
Ligand-Target Pair
DOPA decarboxylase


(Sus scrofa)
BDBM50005742
PNG
((+)-D-m-Tyrosine2-Amino-3-(3-hydroxy-phenyl)-2-met...)
Show SMILES C[C@](N)(Cc1cccc(O)c1)C(O)=O
Show InChI InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-3-2-4-8(12)5-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1
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PubMed
1.00E+6n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against pig kidney L-aromatic amino acid decarboxylase (Dopamine decarboxylase)


J Med Chem 35: 1410-7 (1992)

More data for this
Ligand-Target Pair
DOPA decarboxylase


(Sus scrofa)
BDBM50017850
PNG
(1-(3,4-Dihydroxy-phenyl)-2-methyl-propan-1-one | C...)
Show SMILES CC(C)C(=O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C10H12O3/c1-6(2)10(13)7-3-4-8(11)9(12)5-7/h3-6,11-12H,1-2H3
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PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Orion Corporation Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against the dopamine decarboxylase


J Med Chem 32: 841-6 (1989)

More data for this
Ligand-Target Pair
DOPA decarboxylase


(Sus scrofa)
BDBM50017845
PNG
(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-(3,4,5-trimetho...)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)\C=C\c1cc(O)c(O)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C18H17NO8/c1-25-15-8-11(9-16(26-2)18(15)27-3)13(20)5-4-10-6-12(19(23)24)17(22)14(21)7-10/h4-9,21-22H,1-3H3/b5-4+
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PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Orion Corporation Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against the dopamine decarboxylase


J Med Chem 32: 841-6 (1989)

More data for this
Ligand-Target Pair
DOPA decarboxylase


(Sus scrofa)
BDBM50017857
PNG
(3-(3,4-Dihydroxy-5-nitro-phenyl)-1-phenyl-propenon...)
Show SMILES Oc1cc(\C=C\C(=O)c2ccccc2)cc(c1O)[N+]([O-])=O
Show InChI InChI=1S/C15H11NO5/c17-13(11-4-2-1-3-5-11)7-6-10-8-12(16(20)21)15(19)14(18)9-10/h1-9,18-19H/b7-6+
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PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Orion Corporation Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against the dopamine decarboxylase


J Med Chem 32: 841-6 (1989)

More data for this
Ligand-Target Pair