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Compile Data Set for Download or QSAR

Found 60 hits Enz. Inhib. hit(s) with Target = 'Deoxyribonuclease-1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Deoxyribonuclease-1


(Homo sapiens)
BDBM50052802
PNG
(CHEBI:77181 | CRYSTAL VIOLET | Crystal violet (15)...)
Show SMILES CN(C)c1ccc(cc1)C(=C1C=CC(C=C1)=[N+](C)C)c1ccc(cc1)N(C)C
Show InChI InChI=1S/C25H30N3/c1-26(2)22-13-7-19(8-14-22)25(20-9-15-23(16-10-20)27(3)4)21-11-17-24(18-12-21)28(5)6/h7-18H,1-6H3/q+1
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n/an/a 350n/an/an/an/an/an/a



University of Nis

Curated by ChEMBL


Assay Description
Inhibition of DNase 1 (unknown origin) using (FAM)-labeled dsDNA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121866
PNG
(CHEMBL3617198)
Show SMILES On1c(=O)[nH]c2cc(ccc2c1=O)N1CCCC1
Show InChI InChI=1S/C12H13N3O3/c16-11-9-4-3-8(14-5-1-2-6-14)7-10(9)13-12(17)15(11)18/h3-4,7,18H,1-2,5-6H2,(H,13,17)
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n/an/a 2.79E+4n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121867
PNG
(CHEMBL3617197)
Show SMILES On1c(=O)[nH]c2cc(Nc3ccccc3)ccc2c1=O
Show InChI InChI=1S/C14H11N3O3/c18-13-11-7-6-10(15-9-4-2-1-3-5-9)8-12(11)16-14(19)17(13)20/h1-8,15,20H,(H,16,19)
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n/an/a 3.02E+4n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121882
PNG
(CHEMBL3617285)
Show SMILES Oc1c(nc([nH]c1=O)-c1cccs1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C15H18N4O4S/c20-12-11(14(21)16-3-4-19-5-7-23-8-6-19)17-13(18-15(12)22)10-2-1-9-24-10/h1-2,9,20H,3-8H2,(H,16,21)(H,17,18,22)
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n/an/a 5.89E+4n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121878
PNG
(CHEMBL3617282)
Show SMILES CC(=O)NCCNC(=O)c1nc([nH]c(=O)c1O)-c1cccs1
Show InChI InChI=1S/C13H14N4O4S/c1-7(18)14-4-5-15-12(20)9-10(19)13(21)17-11(16-9)8-3-2-6-22-8/h2-3,6,19H,4-5H2,1H3,(H,14,18)(H,15,20)(H,16,17,21)
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n/an/a 6.26E+4n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121872
PNG
(CHEMBL3617205)
Show SMILES CNC(=O)c1nc([nH]c(=O)c1O)-c1cccs1
Show InChI InChI=1S/C10H9N3O3S/c1-11-9(15)6-7(14)10(16)13-8(12-6)5-3-2-4-17-5/h2-4,14H,1H3,(H,11,15)(H,12,13,16)
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n/an/a 6.76E+4n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121863
PNG
(CHEMBL3617201)
Show SMILES CC(=O)Nc1ccc2[nH]c(=O)n(O)c(=O)c2c1
Show InChI InChI=1S/C10H9N3O4/c1-5(14)11-6-2-3-8-7(4-6)9(15)13(17)10(16)12-8/h2-4,17H,1H3,(H,11,14)(H,12,16)
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n/an/a 8.70E+4n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121699
PNG
(CHEMBL3616998)
Show SMILES Oc1ccc(CNC(=O)c2ccccc2)cc1O
Show InChI InChI=1S/C14H13NO3/c16-12-7-6-10(8-13(12)17)9-15-14(18)11-4-2-1-3-5-11/h1-8,16-17H,9H2,(H,15,18)
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n/an/a>1.00E+5n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121697
PNG
(CHEMBL3617000)
Show SMILES Oc1ccc(CNC(=O)Cc2ccc(Cl)cc2)cc1O
Show InChI InChI=1S/C15H14ClNO3/c16-12-4-1-10(2-5-12)8-15(20)17-9-11-3-6-13(18)14(19)7-11/h1-7,18-19H,8-9H2,(H,17,20)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121696
PNG
(CHEMBL3617001)
Show SMILES Oc1ccc(CNC(=O)Cc2ccccc2Cl)cc1O
Show InChI InChI=1S/C15H14ClNO3/c16-12-4-2-1-3-11(12)8-15(20)17-9-10-5-6-13(18)14(19)7-10/h1-7,18-19H,8-9H2,(H,17,20)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121695
PNG
(CHEMBL3617002)
Show SMILES Oc1ccc(CNC(=O)Cc2ccc(Cl)cc2Cl)cc1O
Show InChI InChI=1S/C15H13Cl2NO3/c16-11-3-2-10(12(17)7-11)6-15(21)18-8-9-1-4-13(19)14(20)5-9/h1-5,7,19-20H,6,8H2,(H,18,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121693
PNG
(CHEMBL3617006)
Show SMILES Oc1ccc(CNC(=O)C2CCCC2)cc1O
Show InChI InChI=1S/C13H17NO3/c15-11-6-5-9(7-12(11)16)8-14-13(17)10-3-1-2-4-10/h5-7,10,15-16H,1-4,8H2,(H,14,17)
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n/an/a>1.00E+5n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121692
PNG
(CHEMBL3617007)
Show SMILES Oc1ccc(CNC(=O)CC2CCCCC2)cc1O
Show InChI InChI=1S/C15H21NO3/c17-13-7-6-12(8-14(13)18)10-16-15(19)9-11-4-2-1-3-5-11/h6-8,11,17-18H,1-5,9-10H2,(H,16,19)
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n/an/a>1.00E+5n/an/an/an/an/an/a



MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121707
PNG
(CHEMBL3617010)
Show SMILES Oc1ccc(CNC(=O)Cc2ccc(cc2)N2CCOCC2)cc1O
Show InChI InChI=1S/C19H22N2O4/c22-17-6-3-15(11-18(17)23)13-20-19(24)12-14-1-4-16(5-2-14)21-7-9-25-10-8-21/h1-6,11,22-23H,7-10,12-13H2,(H,20,24)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121830
PNG
(CHEMBL3617011)
Show SMILES CC(=O)N1CCN(CC(=O)NCc2ccc(O)c(O)c2)CC1
Show InChI InChI=1S/C15H21N3O4/c1-11(19)18-6-4-17(5-7-18)10-15(22)16-9-12-2-3-13(20)14(21)8-12/h2-3,8,20-21H,4-7,9-10H2,1H3,(H,16,22)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121713
PNG
(CHEMBL3617012)
Show SMILES Oc1ccc(CNC(=O)C2CCN(Cc3ccc(F)cc3)CC2)cc1O
Show InChI InChI=1S/C20H23FN2O3/c21-17-4-1-14(2-5-17)13-23-9-7-16(8-10-23)20(26)22-12-15-3-6-18(24)19(25)11-15/h1-6,11,16,24-25H,7-10,12-13H2,(H,22,26)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121714
PNG
(CHEMBL3617013)
Show SMILES Oc1cc2CCN(Cc2cc1O)C(=O)Cc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C17H15Cl2NO3/c18-13-2-1-11(14(19)8-13)7-17(23)20-4-3-10-5-15(21)16(22)6-12(10)9-20/h1-2,5-6,8,21-22H,3-4,7,9H2
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121715
PNG
(CHEMBL3617014)
Show SMILES CN(Cc1ccc(O)c(O)c1)C(=O)Cc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C16H15Cl2NO3/c1-19(9-10-2-5-14(20)15(21)6-10)16(22)7-11-3-4-12(17)8-13(11)18/h2-6,8,20-21H,7,9H2,1H3
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121717
PNG
(CHEMBL3617015)
Show SMILES Oc1ccc(CNC(=O)Cc2ccc(Cl)cc2Cl)c(Cl)c1O
Show InChI InChI=1S/C15H12Cl3NO3/c16-10-3-1-8(11(17)6-10)5-13(21)19-7-9-2-4-12(20)15(22)14(9)18/h1-4,6,20,22H,5,7H2,(H,19,21)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121718
PNG
(CHEMBL3617016)
Show SMILES Oc1cc(F)c(CNC(=O)Cc2ccc(Cl)cc2Cl)cc1O
Show InChI InChI=1S/C15H12Cl2FNO3/c16-10-2-1-8(11(17)5-10)4-15(22)19-7-9-3-13(20)14(21)6-12(9)18/h1-3,5-6,20-21H,4,7H2,(H,19,22)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121719
PNG
(CHEMBL3617017)
Show SMILES Oc1ccc(CNS(=O)(=O)Cc2ccc(Cl)cc2Cl)cc1O
Show InChI InChI=1S/C14H13Cl2NO4S/c15-11-3-2-10(12(16)6-11)8-22(20,21)17-7-9-1-4-13(18)14(19)5-9/h1-6,17-19H,7-8H2
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121721
PNG
(CHEMBL3617018)
Show SMILES Oc1ccc(CC(=O)NCc2ccc(Cl)cc2Cl)cc1O
Show InChI InChI=1S/C15H13Cl2NO3/c16-11-3-2-10(12(17)7-11)8-18-15(21)6-9-1-4-13(19)14(20)5-9/h1-5,7,19-20H,6,8H2,(H,18,21)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121722
PNG
(CHEMBL3617019)
Show SMILES Oc1ccc(CNC(=O)Nc2ccc(Cl)cc2)cc1O
Show InChI InChI=1S/C14H13ClN2O3/c15-10-2-4-11(5-3-10)17-14(20)16-8-9-1-6-12(18)13(19)7-9/h1-7,18-19H,8H2,(H2,16,17,20)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121723
PNG
(CHEMBL3617020)
Show SMILES Oc1ccc(CN2CCN(Cc3ccc(Cl)cc3)C2=O)cc1O
Show InChI InChI=1S/C17H17ClN2O3/c18-14-4-1-12(2-5-14)10-19-7-8-20(17(19)23)11-13-3-6-15(21)16(22)9-13/h1-6,9,21-22H,7-8,10-11H2
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121724
PNG
(CHEMBL3617021)
Show SMILES Oc1ccc(Cc2nc(no2)-c2ccc(Cl)cc2)cc1O
Show InChI InChI=1S/C15H11ClN2O3/c16-11-4-2-10(3-5-11)15-17-14(21-18-15)8-9-1-6-12(19)13(20)7-9/h1-7,19-20H,8H2
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121725
PNG
(CHEMBL3617022)
Show SMILES Oc1ccc(cc1O)-c1nc(Cc2ccc(Cl)cc2)no1
Show InChI InChI=1S/C15H11ClN2O3/c16-11-4-1-9(2-5-11)7-14-17-15(21-18-14)10-3-6-12(19)13(20)8-10/h1-6,8,19-20H,7H2
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121726
PNG
(CHEMBL2443225)
Show SMILES Oc1cc(c[nH]c1=O)-c1ccc(F)cc1
Show InChI InChI=1S/C11H8FNO2/c12-9-3-1-7(2-4-9)8-5-10(14)11(15)13-6-8/h1-6,14H,(H,13,15)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121747
PNG
(CHEMBL3617024)
Show SMILES Oc1cc(c[nH]c1=O)-c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C11H7ClFNO2/c12-8-3-6(1-2-9(8)13)7-4-10(15)11(16)14-5-7/h1-5,15H,(H,14,16)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121750
PNG
(CHEMBL3617025)
Show SMILES CC(=O)Nc1ccc(cc1)-c1c[nH]c(=O)c(O)c1
Show InChI InChI=1S/C13H12N2O3/c1-8(16)15-11-4-2-9(3-5-11)10-6-12(17)13(18)14-7-10/h2-7,17H,1H3,(H,14,18)(H,15,16)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121751
PNG
(CHEMBL3617026)
Show SMILES Cn1ncc2ccc(cc12)-c1c[nH]c(=O)c(O)c1
Show InChI InChI=1S/C13H11N3O2/c1-16-11-4-8(2-3-9(11)7-15-16)10-5-12(17)13(18)14-6-10/h2-7,17H,1H3,(H,14,18)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121752
PNG
(CHEMBL3617028)
Show SMILES Cc1cccc(NCC(=O)N\N=C\c2cc(Br)c(O)c(O)c2Br)c1
Show InChI InChI=1S/C16H15Br2N3O3/c1-9-3-2-4-11(5-9)19-8-13(22)21-20-7-10-6-12(17)15(23)16(24)14(10)18/h2-7,19,23-24H,8H2,1H3,(H,21,22)/b20-7+
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50157846
PNG
(3-Hydroxy-7-p-tolyl-1H-furo[3,2-d]pyrimidine-2,4-d...)
Show SMILES Cc1ccc(cc1)-c1coc2c1[nH]c(=O)n(O)c2=O
Show InChI InChI=1S/C13H10N2O4/c1-7-2-4-8(5-3-7)9-6-19-11-10(9)14-13(17)15(18)12(11)16/h2-6,18H,1H3,(H,14,17)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50157830
PNG
(3-Hydroxy-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-...)
Show SMILES On1c(=O)[nH]c2c(csc2c1=O)-c1ccccc1
Show InChI InChI=1S/C12H8N2O3S/c15-11-10-9(13-12(16)14(11)17)8(6-18-10)7-4-2-1-3-5-7/h1-6,17H,(H,13,16)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50157832
PNG
(3-Hydroxy-4a,7a-dihydro-1H-thieno[2,3-d]pyrimidine...)
Show SMILES On1c(=O)[nH]c2sccc2c1=O
Show InChI InChI=1S/C6H4N2O3S/c9-5-3-1-2-12-4(3)7-6(10)8(5)11/h1-2,11H,(H,7,10)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50157850
PNG
(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Show SMILES On1c(=O)n(Cc2ccccc2)c2sccc2c1=O
Show InChI InChI=1S/C13H10N2O3S/c16-11-10-6-7-19-12(10)14(13(17)15(11)18)8-9-4-2-1-3-5-9/h1-7,18H,8H2
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM33412
PNG
(CHEMBL183852 | N-hydroxy quinazolinedione, 4)
Show SMILES On1c(=O)[nH]c2ccccc2c1=O
Show InChI InChI=1S/C8H6N2O3/c11-7-5-3-1-2-4-6(5)9-8(12)10(7)13/h1-4,13H,(H,9,12)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121865
PNG
(CHEMBL3617199)
Show SMILES CC(=O)Nc1cccc2c1[nH]c(=O)n(O)c2=O
Show InChI InChI=1S/C10H9N3O4/c1-5(14)11-7-4-2-3-6-8(7)12-10(16)13(17)9(6)15/h2-4,17H,1H3,(H,11,14)(H,12,16)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121864
PNG
(CHEMBL3617200)
Show SMILES CC(=O)Nc1ccc2c(c1)[nH]c(=O)n(O)c2=O
Show InChI InChI=1S/C10H9N3O4/c1-5(14)11-6-2-3-7-8(4-6)12-10(16)13(17)9(7)15/h2-4,17H,1H3,(H,11,14)(H,12,16)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121862
PNG
(CHEMBL3617202)
Show SMILES Cn1c2ccccc2c(=O)n(O)c1=O
Show InChI InChI=1S/C9H8N2O3/c1-10-7-5-3-2-4-6(7)8(12)11(14)9(10)13/h2-5,14H,1H3
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121861
PNG
(CHEMBL3617203)
Show SMILES On1c(=O)cc([nH]c1=O)-c1ccccc1
Show InChI InChI=1S/C10H8N2O3/c13-9-6-8(11-10(14)12(9)15)7-4-2-1-3-5-7/h1-6,15H,(H,11,14)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50153250
PNG
(5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...)
Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccs1
Show InChI InChI=1S/C9H6N2O4S/c12-6-5(9(14)15)10-7(11-8(6)13)4-2-1-3-16-4/h1-3,12H,(H,14,15)(H,10,11,13)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121868
PNG
(CHEMBL187010)
Show SMILES COC(=O)c1nc(nc(O)c1O)-c1cccs1
Show InChI InChI=1S/C10H8N2O4S/c1-16-10(15)6-7(13)9(14)12-8(11-6)5-3-2-4-17-5/h2-4,13H,1H3,(H,11,12,14)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121869
PNG
(CHEMBL440562)
Show SMILES OC(=O)c1nc(nc(O)c1O)-c1ccccc1
Show InChI InChI=1S/C11H8N2O4/c14-8-7(11(16)17)12-9(13-10(8)15)6-4-2-1-3-5-6/h1-5,14H,(H,16,17)(H,12,13,15)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121870
PNG
(CHEMBL3617204)
Show SMILES COC(=O)c1nc([nH]c(=O)c1O)-c1ccccc1
Show InChI InChI=1S/C12H10N2O4/c1-18-12(17)8-9(15)11(16)14-10(13-8)7-5-3-2-4-6-7/h2-6,15H,1H3,(H,13,14,16)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50153254
PNG
(5,6-dihydroxy-1-methyl-2-thiophen-2-yl-pyrimidine-...)
Show SMILES Cn1c(nc(C(O)=O)c(O)c1=O)-c1cccs1
Show InChI InChI=1S/C10H8N2O4S/c1-12-8(5-3-2-4-17-5)11-6(10(15)16)7(13)9(12)14/h2-4,13H,1H3,(H,15,16)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121871
PNG
(CHEMBL223338)
Show SMILES NC(=O)c1nc(nc(O)c1O)-c1cccs1
Show InChI InChI=1S/C9H7N3O3S/c10-7(14)5-6(13)9(15)12-8(11-5)4-2-1-3-16-4/h1-3,13H,(H2,10,14)(H,11,12,15)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121873
PNG
(CHEMBL3617206)
Show SMILES CCCNC(=O)c1nc([nH]c(=O)c1O)-c1cccs1
Show InChI InChI=1S/C12H13N3O3S/c1-2-5-13-11(17)8-9(16)12(18)15-10(14-8)7-4-3-6-19-7/h3-4,6,16H,2,5H2,1H3,(H,13,17)(H,14,15,18)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121874
PNG
(CHEMBL3617207)
Show SMILES OCCNC(=O)c1nc([nH]c(=O)c1O)-c1cccs1
Show InChI InChI=1S/C11H11N3O4S/c15-4-3-12-10(17)7-8(16)11(18)14-9(13-7)6-2-1-5-19-6/h1-2,5,15-16H,3-4H2,(H,12,17)(H,13,14,18)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121876
PNG
(CHEMBL3617209)
Show SMILES CCC(C)NC(=O)c1nc([nH]c(=O)c1O)-c1cccs1
Show InChI InChI=1/C13H15N3O3S/c1-3-7(2)14-12(18)9-10(17)13(19)16-11(15-9)8-5-4-6-20-8/h4-7,17H,3H2,1-2H3,(H,14,18)(H,15,16,19)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4104-8 (2015)

More data for this
Ligand-Target Pair
Deoxyribonuclease-1


(Homo sapiens)
BDBM50121700
PNG
(CHEMBL3616997)
Show SMILES Oc1ccc(CNC(=O)Cc2ccccc2)cc1O
Show InChI InChI=1S/C15H15NO3/c17-13-7-6-12(8-14(13)18)10-16-15(19)9-11-4-2-1-3-5-11/h1-8,17-18H,9-10H2,(H,16,19)
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MRC Technology

Curated by ChEMBL


Assay Description
Inhibition of DNAse1 (unknown origin)


Bioorg Med Chem Lett 25: 4097-103 (2015)

More data for this
Ligand-Target Pair
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