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Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50385398
PNG
(CHEMBL2036730)
Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(NC(=O)c2nnc(Nc3ccc(F)c(F)c3)o2)cc1
Show InChI InChI=1S/C23H22F2N4O4/c24-18-10-9-17(12-19(18)25)27-23-29-28-22(33-23)21(32)26-16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-20(30)31/h5-10,12-14H,1-4,11H2,(H,26,32)(H,27,29)(H,30,31)/t13-,14-
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n/an/a 0.5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of rat DGAT1


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM27950
PNG
(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Show SMILES CC1(C)Oc2ncnc(N)c2N=C1c1ccc(cc1)C12CCC(CC(O)=O)(CC1)CC2
Show InChI InChI=1S/C24H28N4O3/c1-22(2)19(28-18-20(25)26-14-27-21(18)31-22)15-3-5-16(6-4-15)24-10-7-23(8-11-24,9-12-24)13-17(29)30/h3-6,14H,7-13H2,1-2H3,(H,29,30)(H2,25,26,27)
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n/an/a 9n/an/an/an/a7.422



AstraZeneca



Assay Description
The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM27947
PNG
(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Show SMILES CC1(C)Oc2ncnc(N)c2N=C1c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1
Show InChI InChI=1S/C22H26N4O3/c1-22(2)19(26-18-20(23)24-12-25-21(18)29-22)16-9-7-15(8-10-16)14-5-3-13(4-6-14)11-17(27)28/h7-10,12-14H,3-6,11H2,1-2H3,(H,27,28)(H2,23,24,25)/t13-,14-
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n/an/a 19n/an/an/an/a7.422



AstraZeneca



Assay Description
The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50355142
PNG
(CHEMBL1835919)
Show SMILES Nc1ncnc2OCCN(c3ccc(cc3)[C@H]3CC[C@H](CC(O)=O)CC3)C(=O)c12
Show InChI InChI=1S/C21H24N4O4/c22-19-18-20(24-12-23-19)29-10-9-25(21(18)28)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-17(26)27/h5-8,12-14H,1-4,9-11H2,(H,26,27)(H2,22,23,24)/t13-,14-
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n/an/a 64n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat DGAT-1


Citation and Details
More data for this
Ligand-Target Pair
Diacylglycerol O-acyltransferase 1


(Rattus norvegicus (rat))
BDBM50399710
PNG
(CHEMBL2178953)
Show SMILES Cc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1
Show InChI InChI=1S/C21H25N3O3/c1-12-19(24-20(21(22)27)13(2)23-12)17-9-7-16(8-10-17)15-5-3-14(4-6-15)11-18(25)26/h7-10,14-15H,3-6,11H2,1-2H3,(H2,22,27)(H,25,26)/t14-,15-
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n/an/a 90n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of DGAT1 in rat adipose tissue assessed as reduction in triacylglycerol synthesis


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50341760
PNG
(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Show SMILES COCCN(C)c1ccc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cn1
Show InChI InChI=1S/C20H19F3N4O3/c1-27(10-11-29-2)15-9-8-14(12-24-15)25-18(28)16-17(20(21,22)23)30-19(26-16)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3,(H,25,28)
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n/an/a 120n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of rat DGAT1


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50399710
PNG
(CHEMBL2178953)
Show SMILES Cc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1
Show InChI InChI=1S/C21H25N3O3/c1-12-19(24-20(21(22)27)13(2)23-12)17-9-7-16(8-10-17)15-5-3-14(4-6-15)11-18(25)26/h7-10,14-15H,3-6,11H2,1-2H3,(H2,22,27)(H,25,26)/t14-,15-
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n/an/a 150n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of DGAT1 in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM27947
PNG
(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Show SMILES CC1(C)Oc2ncnc(N)c2N=C1c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1
Show InChI InChI=1S/C22H26N4O3/c1-22(2)19(26-18-20(23)24-12-25-21(18)29-22)16-9-7-15(8-10-16)14-5-3-13(4-6-14)11-17(27)28/h7-10,12-14H,3-6,11H2,1-2H3,(H,27,28)(H2,23,24,25)/t13-,14-
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n/an/a 3.10E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402756
PNG
(CHEMBL2207805)
Show SMILES O=C(NCc1ccco1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C30H31N3O3/c34-29(31-17-25-2-1-9-35-25)22-3-8-26-27(13-22)33-28(32-26)18-36-24-6-4-23(5-7-24)30-14-19-10-20(15-30)12-21(11-19)16-30/h1-9,13,19-21H,10-12,14-18H2,(H,31,34)(H,32,33)
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n/an/a 4.40E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402753
PNG
(CHEMBL2207808)
Show SMILES O=C(NC[C@H]1CCCO1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C30H35N3O3/c34-29(31-17-25-2-1-9-35-25)22-3-8-26-27(13-22)33-28(32-26)18-36-24-6-4-23(5-7-24)30-14-19-10-20(15-30)12-21(11-19)16-30/h3-8,13,19-21,25H,1-2,9-12,14-18H2,(H,31,34)(H,32,33)/t19?,20?,21?,25-,30?/m1/s1
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n/an/a 8.70E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402748
PNG
(CHEMBL2207794)
Show SMILES CC(C)(C)c1ccc(OCc2nc3ccc(cc3[nH]2)C(=O)NCc2ccco2)cc1
Show InChI InChI=1S/C24H25N3O3/c1-24(2,3)17-7-9-18(10-8-17)30-15-22-26-20-11-6-16(13-21(20)27-22)23(28)25-14-19-5-4-12-29-19/h4-13H,14-15H2,1-3H3,(H,25,28)(H,26,27)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402752
PNG
(CHEMBL2207809)
Show SMILES O=C(NC[C@@H]1CCCO1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C30H35N3O3/c34-29(31-17-25-2-1-9-35-25)22-3-8-26-27(13-22)33-28(32-26)18-36-24-6-4-23(5-7-24)30-14-19-10-20(15-30)12-21(11-19)16-30/h3-8,13,19-21,25H,1-2,9-12,14-18H2,(H,31,34)(H,32,33)/t19?,20?,21?,25-,30?/m0/s1
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n/an/a 9.50E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50208612
PNG
((-)-kurarinone | (2S)-2-(2,4-dihydroxyphenyl)-7-hy...)
Show SMILES COc1cc(O)c(CC(CC=C(C)C)C(C)=C)c2O[C@@H](CC(=O)c12)c1ccc(O)cc1O
Show InChI InChI=1S/C26H30O6/c1-14(2)6-7-16(15(3)4)10-19-21(29)12-24(31-5)25-22(30)13-23(32-26(19)25)18-9-8-17(27)11-20(18)28/h6,8-9,11-12,16,23,27-29H,3,7,10,13H2,1-2,4-5H3/t16?,23-/m0/s1
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n/an/a 1.09E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402762
PNG
(CHEMBL2207799)
Show SMILES O=C(N1CCCC1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C29H33N3O2/c33-28(32-9-1-2-10-32)22-3-8-25-26(14-22)31-27(30-25)18-34-24-6-4-23(5-7-24)29-15-19-11-20(16-29)13-21(12-19)17-29/h3-8,14,19-21H,1-2,9-13,15-18H2,(H,30,31)
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n/an/a 1.13E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402754
PNG
(CHEMBL2207807)
Show SMILES Cc1ccc(CNC(=O)c2ccc3nc(COc4ccc(cc4)C45CC6CC(CC(C6)C4)C5)[nH]c3c2)o1
Show InChI InChI=1S/C31H33N3O3/c1-19-2-6-26(37-19)17-32-30(35)23-3-9-27-28(13-23)34-29(33-27)18-36-25-7-4-24(5-8-25)31-14-20-10-21(15-31)12-22(11-20)16-31/h2-9,13,20-22H,10-12,14-18H2,1H3,(H,32,35)(H,33,34)
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n/an/a 1.14E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402757
PNG
(CHEMBL2207804)
Show SMILES O=C(NCc1ccccn1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C31H32N4O2/c36-30(33-18-25-3-1-2-10-32-25)23-4-9-27-28(14-23)35-29(34-27)19-37-26-7-5-24(6-8-26)31-15-20-11-21(16-31)13-22(12-20)17-31/h1-10,14,20-22H,11-13,15-19H2,(H,33,36)(H,34,35)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402763
PNG
(CHEMBL2207798)
Show SMILES CC(C)NC(=O)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C28H33N3O2/c1-17(2)29-27(32)21-3-8-24-25(12-21)31-26(30-24)16-33-23-6-4-22(5-7-23)28-13-18-9-19(14-28)11-20(10-18)15-28/h3-8,12,17-20H,9-11,13-16H2,1-2H3,(H,29,32)(H,30,31)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402767
PNG
(CHEMBL2205735)
Show SMILES COC(=O)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C26H28N2O3/c1-30-25(29)19-2-7-22-23(11-19)28-24(27-22)15-31-21-5-3-20(4-6-21)26-12-16-8-17(13-26)10-18(9-16)14-26/h2-7,11,16-18H,8-10,12-15H2,1H3,(H,27,28)
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n/an/a 2.30E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402755
PNG
(CHEMBL2207806)
Show SMILES Cc1ccoc1CNC(=O)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C31H33N3O3/c1-19-8-9-36-28(19)17-32-30(35)23-2-7-26-27(13-23)34-29(33-26)18-37-25-5-3-24(4-6-25)31-14-20-10-21(15-31)12-22(11-20)16-31/h2-9,13,20-22H,10-12,14-18H2,1H3,(H,32,35)(H,33,34)
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n/an/a 2.54E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402761
PNG
(CHEMBL2207800)
Show SMILES O=C(N1CCCCC1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C30H35N3O2/c34-29(33-10-2-1-3-11-33)23-4-9-26-27(15-23)32-28(31-26)19-35-25-7-5-24(6-8-25)30-16-20-12-21(17-30)14-22(13-20)18-30/h4-9,15,20-22H,1-3,10-14,16-19H2,(H,31,32)
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n/an/a 2.75E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402766
PNG
(CHEMBL2207795)
Show SMILES OC(=O)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C25H26N2O3/c28-24(29)18-1-6-21-22(10-18)27-23(26-21)14-30-20-4-2-19(3-5-20)25-11-15-7-16(12-25)9-17(8-15)13-25/h1-6,10,15-17H,7-9,11-14H2,(H,26,27)(H,28,29)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402765
PNG
(CHEMBL2207796)
Show SMILES NC(=O)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C25H27N3O2/c26-24(29)18-1-6-21-22(10-18)28-23(27-21)14-30-20-4-2-19(3-5-20)25-11-15-7-16(12-25)9-17(8-15)13-25/h1-6,10,15-17H,7-9,11-14H2,(H2,26,29)(H,27,28)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402764
PNG
(CHEMBL2207797)
Show SMILES CN(C)C(=O)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C27H31N3O2/c1-30(2)26(31)20-3-8-23-24(12-20)29-25(28-23)16-32-22-6-4-21(5-7-22)27-13-17-9-18(14-27)11-19(10-17)15-27/h3-8,12,17-19H,9-11,13-16H2,1-2H3,(H,28,29)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402760
PNG
(CHEMBL2207801)
Show SMILES O=C(Nc1ccccc1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C31H31N3O2/c35-30(32-25-4-2-1-3-5-25)23-6-11-27-28(15-23)34-29(33-27)19-36-26-9-7-24(8-10-26)31-16-20-12-21(17-31)14-22(13-20)18-31/h1-11,15,20-22H,12-14,16-19H2,(H,32,35)(H,33,34)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402759
PNG
(CHEMBL2207802)
Show SMILES CC(C)c1cccc(C(C)C)c1NC(=O)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C37H43N3O2/c1-22(2)30-6-5-7-31(23(3)4)35(30)40-36(41)27-8-13-32-33(17-27)39-34(38-32)21-42-29-11-9-28(10-12-29)37-18-24-14-25(19-37)16-26(15-24)20-37/h5-13,17,22-26H,14-16,18-21H2,1-4H3,(H,38,39)(H,40,41)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402758
PNG
(CHEMBL2207803)
Show SMILES O=C(NCc1ccccc1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C32H33N3O2/c36-31(33-19-21-4-2-1-3-5-21)25-6-11-28-29(15-25)35-30(34-28)20-37-27-9-7-26(8-10-27)32-16-22-12-23(17-32)14-24(13-22)18-32/h1-11,15,22-24H,12-14,16-20H2,(H,33,36)(H,34,35)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402751
PNG
(CHEMBL2207810)
Show SMILES O=C(NCc1cccs1)c1ccc2nc(COc3ccc(cc3)C34CC5CC(CC(C5)C3)C4)[nH]c2c1
Show InChI InChI=1S/C30H31N3O2S/c34-29(31-17-25-2-1-9-36-25)22-3-8-26-27(13-22)33-28(32-26)18-35-24-6-4-23(5-7-24)30-14-19-10-20(15-30)12-21(11-19)16-30/h1-9,13,19-21H,10-12,14-18H2,(H,31,34)(H,32,33)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402749
PNG
(CHEMBL2207812)
Show SMILES O=C(NCc1ccco1)c1ccc2nc(COc3ccc(cc3)-c3ccccc3)[nH]c2c1
Show InChI InChI=1S/C26H21N3O3/c30-26(27-16-22-7-4-14-31-22)20-10-13-23-24(15-20)29-25(28-23)17-32-21-11-8-19(9-12-21)18-5-2-1-3-6-18/h1-15H,16-17H2,(H,27,30)(H,28,29)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair
Diacyl Glycerolacyltransferase 1 (DGAT-1)


(Rattus norvegicus (rat))
BDBM50402750
PNG
(CHEMBL2207811)
Show SMILES O=C(NCc1ccco1)c1ccc2nc(COc3ccccc3)[nH]c2c1
Show InChI InChI=1S/C20H17N3O3/c24-20(21-12-16-7-4-10-25-16)14-8-9-17-18(11-14)23-19(22-17)13-26-15-5-2-1-3-6-15/h1-11H,12-13H2,(H,21,24)(H,22,23)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of DGAT in rat liver microsomes


Citation and Details
More data for this
Ligand-Target Pair