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Found 10 hits Enz. Inhib. hit(s) with Target = 'Dihydrodipicolinate synthase' AND taxid = 83333   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM19472
PNG
(2-oxoacetic acid | Glyoxylate | Oxoethanoic acid |...)
Show SMILES OC(=O)C=O
Show InChI InChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5)
PDB
MMDB

KEGG

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Article
PubMed
1.60E+4n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DHDPS


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50160721
PNG
(2-Oxo-heptanedioic acid | 2-oxoheptanedioic acid |...)
Show SMILES OC(=O)CCCCC(=O)C(O)=O
Show InChI InChI=1S/C7H10O5/c8-5(7(11)12)3-1-2-4-6(9)10/h1-4H2,(H,9,10)(H,11,12)
PDB
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CHEMBL
KEGG
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PDB
UniChem

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Article
PubMed
1.70E+5n/an/an/an/an/an/an/an/a



University of Sydney

Curated by ChEMBL


Assay Description
Binding affinity for Escherichia coli dihydrodipicolinate synthase


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50160721
PNG
(2-Oxo-heptanedioic acid | 2-oxoheptanedioic acid |...)
Show SMILES OC(=O)CCCCC(=O)C(O)=O
Show InChI InChI=1S/C7H10O5/c8-5(7(11)12)3-1-2-4-6(9)10/h1-4H2,(H,9,10)(H,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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CHEMBL
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UniChem

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Article
PubMed
1.70E+5n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DHDPS


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50273974
PNG
(3-fluoro-2-oxopropanoate)
Show SMILES [O-]C(=O)C(=O)CF
Show InChI InChI=1S/C3H3FO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)/p-1
PDB
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PubMed
2.20E+5n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DHDPS


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50273976
PNG
(2-oxopentanoate | 2-oxovalerate | alpha-ketovalera...)
Show SMILES CCCC(=O)C([O-])=O
Show InChI InChI=1S/C5H8O3/c1-2-3-4(6)5(7)8/h2-3H2,1H3,(H,7,8)/p-1
PDB
MMDB

KEGG

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PubMed
7.00E+5n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DHDPS


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50273975
PNG
(2-ketobutyrate | 2-oxobutanate | 2-oxobutanoate | ...)
Show SMILES CCC(=O)C([O-])=O
Show InChI InChI=1S/C4H6O3/c1-2-3(5)4(6)7/h2H2,1H3,(H,6,7)/p-1
PDB
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KEGG

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PubMed
8.30E+5n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DHDPS


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50412477
PNG
(CHEMBL456159)
Show SMILES OC(=O)\C=C\C(=O)\C=C\C(O)=O
Show InChI InChI=1S/C7H6O5/c8-5(1-3-6(9)10)2-4-7(11)12/h1-4H,(H,9,10)(H,11,12)/b3-1+,4-2+
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PubMed
1.63E+6n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli recombinant DHDPS overexpressed with DHDPR assessed as residual activity by modified coupled assay


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50412479
PNG
(CHEMBL456197)
Show SMILES CCOC(=O)\C=C\C(=O)\C=C\C(=O)OCC
Show InChI InChI=1S/C11H14O5/c1-3-15-10(13)7-5-9(12)6-8-11(14)16-4-2/h5-8H,3-4H2,1-2H3/b7-5+,8-6+
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PubMed
4.95E+6n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli recombinant DHDPS overexpressed with DHDPR assessed as residual activity by modified coupled assay


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50412478
PNG
(CHEMBL178492)
Show SMILES CCOC(=O)CCC(=O)C=CC(=O)OCC
Show InChI InChI=1S/C11H16O5/c1-3-15-10(13)7-5-9(12)6-8-11(14)16-4-2/h5,7H,3-4,6,8H2,1-2H3
PDB
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KEGG

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CHEMBL
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UniChem
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Article
PubMed
1.09E+7n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli recombinant DHDPS overexpressed with DHDPR assessed as residual activity by modified coupled assay


Citation and Details
More data for this
Ligand-Target Pair
Dihydrodipicolinate synthase


(Escherichia coli (strain K12))
BDBM50412480
PNG
(CHEMBL458071)
Show SMILES OC(=O)CCC(=O)C=CC(O)=O
Show InChI InChI=1S/C7H8O5/c8-5(1-3-6(9)10)2-4-7(11)12/h1,3H,2,4H2,(H,9,10)(H,11,12)
PDB
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CHEMBL
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PC sid
UniChem
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Article
PubMed
3.24E+7n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli recombinant DHDPS overexpressed with DHDPR assessed as residual activity by modified coupled assay


Citation and Details
More data for this
Ligand-Target Pair