BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Dihydroorotase' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotase


(Mus musculus)
BDBM50405110
PNG
(CHEMBL306140)
Show SMILES OC(=O)C1CS(=O)CC(=O)N1
Show InChI InChI=1S/C5H7NO4S/c7-4-2-11(10)1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 1.80E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37


J Med Chem 27: 228-32 (1984)

More data for this
Ligand-Target Pair
Dihydroorotase


(Mus musculus)
BDBM50405111
PNG
(CHEMBL73819)
Show SMILES OC(=O)C1CS(=O)(=O)NC(=O)N1
Show InChI InChI=1S/C4H6N2O5S/c7-3(8)2-1-12(10,11)6-4(9)5-2/h2H,1H2,(H,7,8)(H2,5,6,9)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 5.20E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37


J Med Chem 27: 228-32 (1984)

More data for this
Ligand-Target Pair
Dihydroorotase


(Mus musculus)
BDBM50405112
PNG
(CHEMBL308628)
Show SMILES NC(=O)NC(CP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C4H9N2O6P/c5-4(9)6-2(3(7)8)1-13(10,11)12/h2H,1H2,(H,7,8)(H3,5,6,9)(H2,10,11,12)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37


J Med Chem 27: 228-32 (1984)

More data for this
Ligand-Target Pair
Dihydroorotase


(Mus musculus)
BDBM50405109
PNG
(CHEMBL1627199)
Show SMILES CS1(=O)=NC(=O)NC(=C1)C(O)=O
Show InChI InChI=1S/C5H8N2O4S/c1-12(11)2-3(4(8)9)6-5(10)7-12/h2,12H,1H3,(H,8,9)(H2,6,7,10,11)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of dihydroorotase enzyme from mouse Ehrlich ascites at the concentration of 10 uM and at pH 7.37


J Med Chem 27: 228-32 (1984)

More data for this
Ligand-Target Pair