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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Dihydroorotase (DHO)' AND taxid = 83333   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotase (DHO)


(Escherichia coli)
BDBM85254
PNG
(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Show SMILES [O-]C(=O)[C@@H]1CC(=O)CC(=O)N1
Show InChI InChI=1S/C6H7NO4/c8-3-1-4(6(10)11)7-5(9)2-3/h4H,1-2H2,(H,7,9)(H,10,11)/p-1/t4-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
7.60E+7n/an/an/an/an/an/a7.0n/a



Texas A&M University



Assay Description
The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...


Citation and Details
More data for this
Ligand-Target Pair
Dihydroorotase (DHO)


(Escherichia coli)
BDBM85254
PNG
(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Show SMILES [O-]C(=O)[C@@H]1CC(=O)CC(=O)N1
Show InChI InChI=1S/C6H7NO4/c8-3-1-4(6(10)11)7-5(9)2-3/h4H,1-2H2,(H,7,9)(H,10,11)/p-1/t4-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
2.10E+8n/an/an/an/an/an/a8.0n/a



Texas A&M University



Assay Description
The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...


Citation and Details
More data for this
Ligand-Target Pair
Dihydroorotase (DHO)


(Escherichia coli)
BDBM85254
PNG
(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Show SMILES [O-]C(=O)[C@@H]1CC(=O)CC(=O)N1
Show InChI InChI=1S/C6H7NO4/c8-3-1-4(6(10)11)7-5(9)2-3/h4H,1-2H2,(H,7,9)(H,10,11)/p-1/t4-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
4.40E+8n/an/an/an/an/an/a9.0n/a



Texas A&M University



Assay Description
The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...


Citation and Details
More data for this
Ligand-Target Pair