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Found 8 hits Enz. Inhib. hit(s) with Target = 'Dihydropteroate synthetase, putative' AND taxid = 5823   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50029764
PNG
(1,1'-sulfonylbis(4-aminobenzene) | 4,4'-Sulfonylbi...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
KEGG

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Article
PubMed
n/an/a 1.24E+4n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50099670
PNG
(2-(4-(4-aminophenylsulfonyl)phenylamino)acetic aci...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)c1ccc(NCC(O)=O)cc1
Show InChI InChI=1S/C14H14N2O4S/c15-10-1-5-12(6-2-10)21(19,20)13-7-3-11(4-8-13)16-9-14(17)18/h1-8,16H,9,15H2,(H,17,18)
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PubMed
n/an/a 1.78E+4n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50391261
PNG
(CHEMBL139596)
Show SMILES CN(C)c1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C14H16N2O2S/c1-16(2)12-5-9-14(10-6-12)19(17,18)13-7-3-11(15)4-8-13/h3-10H,15H2,1-2H3
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Article
PubMed
n/an/a 2.15E+4n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50391254
PNG
(CHEMBL353260)
Show SMILES CNc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C13H14N2O2S/c1-15-11-4-8-13(9-5-11)18(16,17)12-6-2-10(14)3-7-12/h2-9,15H,14H2,1H3
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Article
PubMed
n/an/a 2.67E+4n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50391267
PNG
(CHEMBL1246 | Mono-N-Acetyl Dapsone)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C14H14N2O3S/c1-10(17)16-12-4-8-14(9-5-12)20(18,19)13-6-2-11(15)3-7-13/h2-9H,15H2,1H3,(H,16,17)
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PubMed
n/an/a 3.33E+4n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50391249
PNG
(CHEMBL142844)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C13H13NO2S/c1-10-2-6-12(7-3-10)17(15,16)13-8-4-11(14)5-9-13/h2-9H,14H2,1H3
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CHEMBL
PC cid
PC sid
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Article
PubMed
n/an/a 4.80E+4n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50391266
PNG
(CHEMBL357499)
Show SMILES Nc1ccc(cc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C12H11NO2S/c13-10-6-8-12(9-7-10)16(14,15)11-4-2-1-3-5-11/h1-9H,13H2
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CHEMBL
PC cid
PC sid
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Article
PubMed
n/an/a 1.04E+5n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair
Dihydropteroate synthetase, putative


(Plasmodium berghei str. ANKA)
BDBM50391239
PNG
(CHEMBL140585)
Show SMILES COC(=O)c1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C14H13NO4S/c1-19-14(16)10-2-6-12(7-3-10)20(17,18)13-8-4-11(15)5-9-13/h2-9H,15H2,1H3
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CHEMBL
PC cid
PC sid
UniChem
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Article
PubMed
n/an/a 1.47E+5n/an/an/an/an/an/a



Leibniz Center for Medicine and Biosciences

Curated by ChEMBL


Assay Description
Inhibitory activity against dihydropteroic acid synthase (SYN) from Plasmodium berghei


Citation and Details
More data for this
Ligand-Target Pair