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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 9 (DDP9 D301A)' AND taxid = 9606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 9 (DDP9 D301A)


(Homo sapiens (Human))
BDBM213827
PNG
(E67 interacting loop (EIL) | SLRFLFEGQRIADNH)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C80H123N25O23/c1-8-42(6)64(77(126)93-43(7)65(114)98-57(35-63(112)113)76(125)103-56(34-60(83)108)75(124)104-58(78(127)128)33-46-36-88-39-92-46)105-70(119)49(22-16-28-90-80(86)87)95-69(118)51(23-25-59(82)107)94-61(109)37-91-67(116)50(24-26-62(110)111)97-73(122)54(31-44-17-11-9-12-18-44)102-72(121)53(30-41(4)5)100-74(123)55(32-45-19-13-10-14-20-45)101-68(117)48(21-15-27-89-79(84)85)96-71(120)52(29-40(2)3)99-66(115)47(81)38-106/h9-14,17-20,36,39-43,47-58,64,106H,8,15-16,21-35,37-38,81H2,1-7H3,(H2,82,107)(H2,83,108)(H,88,92)(H,91,116)(H,93,126)(H,94,109)(H,95,118)(H,96,120)(H,97,122)(H,98,114)(H,99,115)(H,100,123)(H,101,117)(H,102,121)(H,103,125)(H,104,124)(H,105,119)(H,110,111)(H,112,113)(H,127,128)(H4,84,85,89)(H4,86,87,90)/t42-,43-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,64-/m0/s1
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.39E+4n/an/an/an/an/an/an/an/a



Georg-August-University of Goettingen



Assay Description
All assays were performed in TB supplemented with 0.2% Tween 20. For inhibition assays, recombinant DPP9 (25 nM) purified from insect cells was incub...


J Biol Chem 288: 32787-96 (2013)


Article DOI: 10.1074/jbc.M113.489179
BindingDB Entry DOI: 10.7270/Q2VX0FBJ
More data for this
Ligand-Target Pair