BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 32 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase-IV (DDP-4)' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM50228403
PNG
((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)
Show SMILES CC#CCn1c(nc2n(C)c(=O)n(Cc3nc(C)c4ccccc4n3)c(=O)c12)N1CCC[C@@H](N)C1
Show InChI InChI=1S/C25H28N8O2/c1-4-5-13-32-21-22(29-24(32)31-12-8-9-17(26)14-31)30(3)25(35)33(23(21)34)15-20-27-16(2)18-10-6-7-11-19(18)28-20/h6-7,10-11,17H,8-9,12-15,26H2,1-3H3/t17-/m1/s1
PDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PDB
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM16285
PNG
(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)
Show SMILES Cn1c(=O)cc(N2CCC[C@@H](N)C2)n(Cc2ccccc2C#N)c1=O
Show InChI InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1
PDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PDB
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM11162
PNG
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1
PDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PDB
Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167935
PNG
(1,5-Dimethyl-2-phenyl-4-(6-(phenylsulfonyl)tetrazo...)
Show SMILES Cc1c(-c2c(cnc3nnnn23)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C21H17N7O3S/c1-14-18(20(29)28(26(14)2)15-9-5-3-6-10-15)19-17(13-22-21-23-24-25-27(19)21)32(30,31)16-11-7-4-8-12-16/h3-13H,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167938
PNG
(1',5'-Dimethyl-2'-phenyl-5-(phenylsulf...)
Show SMILES Cc1c(-c2cc(n[nH]2)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C20H18N4O3S/c1-14-19(20(25)24(23(14)2)15-9-5-3-6-10-15)17-13-18(22-21-17)28(26,27)16-11-7-4-8-12-16/h3-13H,1-2H3,(H,21,22)
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM170166
PNG
((R)-40)
Show SMILES CC(C)=CCn1c(nc2n(C)c(=O)n(Cc3ccccc3C#N)c(=O)c12)N1CCC[C@@H](N)C1
Show InChI InChI=1/C24H29N7O2/c1-16(2)10-12-30-20-21(27-23(30)29-11-6-9-19(26)15-29)28(3)24(33)31(22(20)32)14-18-8-5-4-7-17(18)13-25/h4-5,7-8,10,19H,6,9,11-12,14-15,26H2,1-3H3/t19-/s2
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 23.5n/an/an/an/an/an/a



West China Hospital



Assay Description
DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM170168
PNG
((R)-43)
Show SMILES CC(C)=CCn1c(nc2n(C)c(=O)n(Cc3nc4ccccc4s3)c(=O)c12)N1CCC[C@@H](N)C1
Show InChI InChI=1/C24H29N7O2S/c1-15(2)10-12-30-20-21(27-23(30)29-11-6-7-16(25)13-29)28(3)24(33)31(22(20)32)14-19-26-17-8-4-5-9-18(17)34-19/h4-5,8-10,16H,6-7,11-14,25H2,1-3H3/t16-/s2
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 36.2n/an/an/an/an/an/a



West China Hospital



Assay Description
DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM170169
PNG
((S)-43)
Show SMILES CC(C)=CCn1c(nc2n(C)c(=O)n(Cc3nc4ccccc4s3)c(=O)c12)N1CCC[C@H](N)C1
Show InChI InChI=1/C24H29N7O2S/c1-15(2)10-12-30-20-21(27-23(30)29-11-6-7-16(25)13-29)28(3)24(33)31(22(20)32)14-19-26-17-8-4-5-9-18(17)34-19/h4-5,8-10,16H,6-7,11-14,25H2,1-3H3/t16-/s2
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 36.9n/an/an/an/an/an/a



West China Hospital



Assay Description
DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167943
PNG
(3-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1Hpyraz...)
Show SMILES Cc1c(-c2c(C#N)c3nc4ccccc4n3cc2S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C29H21N5O3S/c1-19-26(29(35)34(32(19)2)20-11-5-3-6-12-20)27-22(17-30)28-31-23-15-9-10-16-24(23)33(28)18-25(27)38(36,37)21-13-7-4-8-14-21/h3-16,18H,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a>50n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167944
PNG
(1,5-Dimethyl-4-(3-methyl-1-phenyl-5-(phenylsulfony...)
Show SMILES Cc1nn(-c2ccccc2)c2nc(-c3c(C)n(C)n(-c4ccccc4)c3=O)c(cc12)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C30H25N5O3S/c1-20-25-19-26(39(37,38)24-17-11-6-12-18-24)28(31-29(25)34(32-20)22-13-7-4-8-14-22)27-21(2)33(3)35(30(27)36)23-15-9-5-10-16-23/h4-19H,1-3H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>50n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167936
PNG
(1,5-Dimethyl-2-phenyl-4-(3-(phenylsulfonyl)benzo[4...)
Show SMILES Cc1c(-c2c(cnc3nc4ccccc4n23)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C27H21N5O3S/c1-18-24(26(33)32(30(18)2)19-11-5-3-6-12-19)25-23(36(34,35)20-13-7-4-8-14-20)17-28-27-29-21-15-9-10-16-22(21)31(25)27/h3-17H,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 73n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167932
PNG
(1,5-Dimethyl-2-phenyl-4-(6-(phenylsulfonyl)-[1,2,4...)
Show SMILES Cc1c(-c2c(cnc3ncnn23)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C22H18N6O3S/c1-15-19(21(29)28(26(15)2)16-9-5-3-6-10-16)20-18(13-23-22-24-14-25-27(20)22)32(30,31)17-11-7-4-8-12-17/h3-14H,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 107n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM170167
PNG
((S)-40)
Show SMILES CC(C)=CCn1c(nc2n(C)c(=O)n(Cc3ccccc3C#N)c(=O)c12)N1CCC[C@H](N)C1
Show InChI InChI=1/C24H29N7O2/c1-16(2)10-12-30-20-21(27-23(30)29-11-6-9-19(26)15-29)28(3)24(33)31(22(20)32)14-18-8-5-4-7-17(18)13-25/h4-5,7-8,10,19H,6,9,11-12,14-15,26H2,1-3H3/t19-/s2
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 108n/an/an/an/an/an/a



West China Hospital



Assay Description
DPP-IV inhibition was measured by DPP-IV inhibitor screening assay kit (Cayman Chemical Company, Item No. 700210) following the manufacturer's in...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167933
PNG
(7-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyra...)
Show SMILES Cc1c(-c2c(cnc3c(cnn23)C#N)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C24H18N6O3S/c1-16-21(24(31)30(28(16)2)18-9-5-3-6-10-18)22-20(34(32,33)19-11-7-4-8-12-19)15-26-23-17(13-25)14-27-29(22)23/h3-12,14-15H,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 112n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166622
PNG
((2-(2,4-Dichlorophenyl)imidazo[1,2-a]pyridin-3-yl)...)
Show SMILES NCc1c(nc2ccccn12)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C14H11Cl2N3/c15-9-4-5-10(11(16)7-9)14-12(8-17)19-6-2-1-3-13(19)18-14/h1-7H,8,17H2
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166624
PNG
((2-(o-Tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine...)
Show SMILES Cc1ccccc1-c1nc2ccccn2c1CN
Show InChI InChI=1S/C15H15N3/c1-11-6-2-3-7-12(11)15-13(10-16)18-9-5-4-8-14(18)17-15/h2-9H,10,16H2,1H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 290n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167934
PNG
(1,5-Dimethyl-2-phenyl-4-(2-phenyl-6-(phenylsulfony...)
Show SMILES Cc1c(-c2c(cnc3cc(nn23)-c2ccccc2)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C29H23N5O3S/c1-20-27(29(35)34(32(20)2)22-14-8-4-9-15-22)28-25(38(36,37)23-16-10-5-11-17-23)19-30-26-18-24(31-33(26)28)21-12-6-3-7-13-21/h3-19H,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 313n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166623
PNG
((2-(2,5-Dichlorophenyl)imidazo[1,2-a]pyridin-3-yl)...)
Show SMILES NCc1c(nc2ccccn12)-c1cc(Cl)ccc1Cl
Show InChI InChI=1S/C14H11Cl2N3/c15-9-4-5-11(16)10(7-9)14-12(8-17)19-6-2-1-3-13(19)18-14/h1-7H,8,17H2
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 650n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166627
PNG
((7-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...)
Show SMILES Cc1ccc(cc1)-c1nc2cc(C)ccn2c1CN
Show InChI InChI=1S/C16H17N3/c1-11-3-5-13(6-4-11)16-14(10-17)19-8-7-12(2)9-15(19)18-16/h3-9H,10,17H2,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 840n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166625
PNG
((2-(4-Bromophenyl)imidazo[1,2-a]pyridin-3-yl)metha...)
Show SMILES NCc1c(nc2ccccn12)-c1ccc(Br)cc1
Show InChI InChI=1S/C14H12BrN3/c15-11-6-4-10(5-7-11)14-12(9-16)18-8-2-1-3-13(18)17-14/h1-8H,9,16H2
PDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 940n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167939
PNG
(1',5'-Dimethyl-2,2'-diphenyl-5-(phenyl...)
Show SMILES Cc1c(-c2cc(nn2-c2ccccc2)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C26H22N4O3S/c1-19-25(26(31)30(28(19)2)21-14-8-4-9-15-21)23-18-24(27-29(23)20-12-6-3-7-13-20)34(32,33)22-16-10-5-11-17-22/h3-18H,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.64E+3n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166621
PNG
((2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl)meth...)
Show SMILES NCc1c(nc2ccccn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C14H12ClN3/c15-11-6-4-10(5-7-11)14-12(9-16)18-8-2-1-3-13(18)17-14/h1-8H,9,16H2
PDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6.46E+3n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166626
PNG
((6-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...)
Show SMILES Cc1ccc(cc1)-c1nc2ccc(C)cn2c1CN
Show InChI InChI=1S/C16H17N3/c1-11-3-6-13(7-4-11)16-14(9-17)19-10-12(2)5-8-15(19)18-16/h3-8,10H,9,17H2,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.46E+3n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167931
PNG
(1,5-dimethyl-2-phenyl-4-(2-(phenylsulfonyl)acetyl)...)
Show SMILES Cc1c(C(=O)CS(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C19H18N2O4S/c1-14-18(17(22)13-26(24,25)16-11-7-4-8-12-16)19(23)21(20(14)2)15-9-5-3-6-10-15/h3-12H,13H2,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.01E+4n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166619
PNG
((2-Phenylimidazo[1,2-a]pyridin-3-yl)methanamine hy...)
Show SMILES NCc1c(nc2ccccn12)-c1ccccc1
Show InChI InChI=1S/C14H13N3/c15-10-12-14(11-6-2-1-3-7-11)16-13-8-4-5-9-17(12)13/h1-9H,10,15H2
PDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.37E+4n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167937
PNG
(4-(8,10-Dimethyl-3-(phenylsulfonyl)pyrido[2',3...)
Show SMILES Cc1c(-c2c(cnc3c4c(C)cc(C)nc4nn23)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C28H24N6O3S/c1-17-15-18(2)30-26-23(17)27-29-16-22(38(36,37)21-13-9-6-10-14-21)25(33(27)31-26)24-19(3)32(4)34(28(24)35)20-11-7-5-8-12-20/h5-16H,1-4H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.45E+4n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167940
PNG
(6-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1Hpyraz...)
Show SMILES Cc1c(-c2[nH]c(=O)c(cc2S(=O)(=O)c2ccccc2)C#N)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C23H18N4O4S/c1-15-20(23(29)27(26(15)2)17-9-5-3-6-10-17)21-19(13-16(14-24)22(28)25-21)32(30,31)18-11-7-4-8-12-18/h3-13H,1-2H3,(H,25,28)
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.73E+4n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167941
PNG
(Ethyl 6-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1...)
Show SMILES CCOC(=O)c1cc(c(nc1C)-c1c(C)n(C)n(-c2ccccc2)c1=O)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H25N3O5S/c1-5-34-26(31)21-16-22(35(32,33)20-14-10-7-11-15-20)24(27-17(21)2)23-18(3)28(4)29(25(23)30)19-12-8-6-9-13-19/h6-16H,5H2,1-4H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.76E+4n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM167942
PNG
(Ethyl 6-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1...)
Show SMILES CCOC(=O)c1cc(c(nc1-c1ccccc1)-c1c(C)n(C)n(-c2ccccc2)c1=O)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C31H27N3O5S/c1-4-39-31(36)25-20-26(40(37,38)24-18-12-7-13-19-24)29(32-28(25)22-14-8-5-9-15-22)27-21(2)33(3)34(30(27)35)23-16-10-6-11-17-23/h5-20H,4H2,1-3H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.83E+4n/an/an/an/an/an/a



Cairo University



Assay Description
A 200-無 reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166628
PNG
((8-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...)
Show SMILES Cc1ccc(cc1)-c1nc2c(C)cccn2c1CN
Show InChI InChI=1S/C16H17N3/c1-11-5-7-13(8-6-11)15-14(10-17)19-9-3-4-12(2)16(19)18-15/h3-9H,10,17H2,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166620
PNG
((2-(3-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl)meth...)
Show SMILES NCc1c(nc2ccccn12)-c1cccc(Cl)c1
Show InChI InChI=1S/C14H12ClN3/c15-11-5-3-4-10(8-11)14-12(9-16)18-7-2-1-6-13(18)17-14/h1-8H,9,16H2
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166629
PNG
(Methyl 3-(aminomethyl)-2-(p-tolyl)imidazo[1,2-a]py...)
Show SMILES COC(=O)c1ccc2nc(c(CN)n2c1)-c1ccc(C)cc1
Show InChI InChI=1S/C17H17N3O2/c1-11-3-5-12(6-4-11)16-14(9-18)20-10-13(17(21)22-2)7-8-15(20)19-16/h3-8,10H,9,18H2,1-2H3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Citation and Details
More data for this
Ligand-Target Pair