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Found 8 hits Enz. Inhib. hit(s) with Target = 'Disulfide bond formation protein B (DsbB)' AND taxid = 83333   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM81417
PNG
(Fragment 1)
Show SMILES CC1=C2CC(CCC2(C)CCC1=O)C(C)(C)O
Show InChI InChI=1S/C15H24O2/c1-10-12-9-11(14(2,3)17)5-7-15(12,4)8-6-13(10)16/h11,17H,5-9H2,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.00E+3n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM41732
PNG
(1-benzyl-2,5-dimethyl-pyrrole-3-carboxylic acid | ...)
Show SMILES Cc1cc(C(O)=O)c(C)n1Cc1ccccc1
Show InChI InChI=1S/C14H15NO2/c1-10-8-13(14(16)17)11(2)15(10)9-12-6-4-3-5-7-12/h3-8H,9H2,1-2H3,(H,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.30E+4n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM50042278
PNG
(7-Chloro-1H-quinoline-2,4-dione | CHEMBL112809 | F...)
Show SMILES Oc1cc(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C9H6ClNO2/c10-5-1-2-6-7(3-5)11-9(13)4-8(6)12/h1-4H,(H2,11,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.60E+4n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM81420
PNG
(Fragment 6)
Show SMILES OC(=O)C1CCN(CC1)C(=O)c1scc2OCCOc12
Show InChI InChI=1S/C13H15NO5S/c15-12(14-3-1-8(2-4-14)13(16)17)11-10-9(7-20-11)18-5-6-19-10/h7-8H,1-6H2,(H,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.00E+4n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM81418
PNG
(Fragment 2)
Show SMILES CCC(=O)C1C(=O)CC(C)(C)C(C1=O)c1ccccc1
Show InChI InChI=1S/C17H20O3/c1-4-12(18)14-13(19)10-17(2,3)15(16(14)20)11-8-6-5-7-9-11/h5-9,14-15H,4,10H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.00E+5n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM81421
PNG
(Fragment 7)
Show SMILES Cc1ccc2scc(CC(O)=O)c2c1
Show InChI InChI=1S/C11H10O2S/c1-7-2-3-10-9(4-7)8(6-14-10)5-11(12)13/h2-4,6H,5H2,1H3,(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1.15E+5n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM42347
PNG
((2,2-dimethyl-4-oxo-3,4-dihydro-1,5-benzothiazepin...)
Show SMILES CC1(C)CC(=O)N(CC(O)=O)c2ccccc2S1
Show InChI InChI=1S/C13H15NO3S/c1-13(2)7-11(15)14(8-12(16)17)9-5-3-4-6-10(9)18-13/h3-6H,7-8H2,1-2H3,(H,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.68E+5n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair
Disulfide bond formation protein B (DsbB)


(Escherichia coli)
BDBM81419
PNG
(Fragment 3)
Show SMILES Oc1ccc(NC(=O)COc2ccccc2)cc1
Show InChI InChI=1S/C14H13NO3/c16-12-8-6-11(7-9-12)15-14(17)10-18-13-4-2-1-3-5-13/h1-9,16H,10H2,(H,15,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
n/an/a 1.93E+5n/an/an/an/a6.230



Leiden University



Assay Description
13 fragments with strong inhibition in the single concentration point assay were chose from the micelle screen for further analysis using a biochemic...


Citation and Details
More data for this
Ligand-Target Pair