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Found 18 hits Enz. Inhib. hit(s) with Target = 'Dopamine2-like' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine2-like


(HUMAN)
BDBM50005120
PNG
(CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...)
Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C
Show InChI InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1
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15n/an/an/an/an/an/an/an/a



University of Toronto

Curated by PDSP Ki Database




Citation and Details
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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM21397
PNG
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1
Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)
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15n/an/an/an/an/an/an/an/a



University of Toronto

Curated by PDSP Ki Database




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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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60n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM85047
PNG
(SDZ GLC 756)
Show SMILES CN1C[C@H](CSc2ccccn2)C[C@@H]2Cc3c(O)cccc3C[C@@H]12
Show InChI InChI=1S/C20H24N2OS/c1-22-12-14(13-24-20-7-2-3-8-21-20)9-16-10-17-15(11-18(16)22)5-4-6-19(17)23/h2-8,14,16,18,23H,9-13H2,1H3/t14-,16-,18-/m1/s1
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75n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM81993
PNG
(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Show SMILES CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C
Show InChI InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1
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110n/an/an/an/an/an/an/an/a



University of Toronto

Curated by PDSP Ki Database




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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM50001888
PNG
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
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400n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM82479
PNG
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE)
Show SMILES CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1
Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
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800n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM55121
PNG
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Show SMILES NCCc1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2
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880n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM22869
PNG
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3
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2.50E+3n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM35234
PNG
(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)
Show SMILES NCC(O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2
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3.13E+3n/an/an/an/an/an/an/an/a



University of Toronto

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More data for this
Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM50007422
PNG
((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1
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3.20E+3n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM81774
PNG
(CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sul...)
Show SMILES CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O
Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
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3.33E+3n/an/an/an/an/an/an/an/a



University of Toronto

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM50091032
PNG
(6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-a...)
Show SMILES [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1
Show InChI InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/p+1/t8-/m1/s1
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4.20E+3n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
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4.30E+3n/an/an/an/an/an/an/an/a



University of Toronto

Curated by PDSP Ki Database




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More data for this
Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM81775
PNG
(Sulpiride-R | Sulpiride-d | Sulpiride-high,(-) | S...)
Show SMILES CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O
Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1
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4.63E+3n/an/an/an/an/an/an/an/a



University of Toronto

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More data for this
Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM50007422
PNG
((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31
Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair
Dopamine2-like


(HUMAN)
BDBM82247
PNG
(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)
Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1
Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



University of Toronto

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Ligand-Target Pair