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Found 12 hits Enz. Inhib. hit(s) with Target = 'ERO1-like protein alpha' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ERO1-like protein alpha


(Homo sapiens)
BDBM50336422
PNG
(2-bromo-4-((1-(4-bromophenyl)-3,5-dioxopyrazolidin...)
Show SMILES COc1cc(C=C2C(=O)NN(C2=O)c2ccc(Br)cc2)cc(Br)c1OC(C)=O
Show InChI InChI=1S/C19H14Br2N2O5/c1-10(24)28-17-15(21)8-11(9-16(17)27-2)7-14-18(25)22-23(19(14)26)13-5-3-12(20)4-6-13/h3-9H,1-2H3,(H,22,25)
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n/an/a 3.00E+3n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336424
PNG
(1-(4-chlorophenyl)-4-(3,4-dimethoxybenzylidene)-3-...)
Show SMILES COc1ccc(\C=C2\C(=O)N(N=C2C(F)(F)F)c2ccc(Cl)cc2)cc1OC
Show InChI InChI=1S/C19H14ClF3N2O3/c1-27-15-8-3-11(10-16(15)28-2)9-14-17(19(21,22)23)24-25(18(14)26)13-6-4-12(20)5-7-13/h3-10H,1-2H3/b14-9+
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n/an/a 8.00E+3n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336428
PNG
(2-(4,5-dinitro-1H-imidazol-1-yl)-N-(3-nitro-5-phen...)
Show SMILES O[N+](=O)c1c(ncn1CC(=O)Nc1cc(Oc2ccccc2)cc(c1)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C17H12N6O8/c24-15(9-20-10-18-16(22(27)28)17(20)23(29)30)19-11-6-12(21(25)26)8-14(7-11)31-13-4-2-1-3-5-13/h1-8,10H,9H2,(H-,19,24,29,30)/p+1
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n/an/a 1.00E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336430
PNG
(1-(4-chlorophenyl)-5-(3,4-dihydroxybenzylidene)pyr...)
Show SMILES Oc1ccc(C=C2C(=O)NC(=O)N(C2=O)c2ccc(Cl)cc2)cc1O
Show InChI InChI=1S/C17H11ClN2O5/c18-10-2-4-11(5-3-10)20-16(24)12(15(23)19-17(20)25)7-9-1-6-13(21)14(22)8-9/h1-8,21-22H,(H,19,23,25)
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n/an/a 1.10E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336431
PNG
(5-(3-ethoxy-4-(2-(naphthalen-1-yloxy)ethoxy)benzyl...)
Show SMILES CCOc1cc(C=C2C(=O)NC(=O)N(C2=O)c2ccc(C)cc2)ccc1OCCOc1cccc2ccccc12
Show InChI InChI=1S/C32H28N2O6/c1-3-38-29-20-22(19-26-30(35)33-32(37)34(31(26)36)24-14-11-21(2)12-15-24)13-16-28(29)40-18-17-39-27-10-6-8-23-7-4-5-9-25(23)27/h4-16,19-20H,3,17-18H2,1-2H3,(H,33,35,37)
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n/an/a 1.70E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336432
PNG
(5-(3-methoxy-4-(2-(3-methoxyphenoxy)ethoxy)benzyli...)
Show SMILES COc1ccc(cc1)N1C(=O)NC(=O)C(=Cc2ccc(OCCOc3cccc(OC)c3)c(OC)c2)C1=O
Show InChI InChI=1S/C28H26N2O8/c1-34-20-10-8-19(9-11-20)30-27(32)23(26(31)29-28(30)33)15-18-7-12-24(25(16-18)36-3)38-14-13-37-22-6-4-5-21(17-22)35-2/h4-12,15-17H,13-14H2,1-3H3,(H,29,31,33)
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n/an/a 2.40E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336429
PNG
(3-(4-nitrobenzamido)-9,10-dioxo-9,10-dihydroanthra...)
Show SMILES OC(=O)c1cc2C(=O)c3ccccc3C(=O)c2cc1NC(=O)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C22H12N2O7/c25-19-13-3-1-2-4-14(13)20(26)16-10-18(17(22(28)29)9-15(16)19)23-21(27)11-5-7-12(8-6-11)24(30)31/h1-10H,(H,23,27)(H,28,29)
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n/an/a 3.70E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336423
PNG
(4-(5-chloro-2-hydroxy-3-methoxybenzylidene)-1-(3-c...)
Show SMILES COc1cc(Cl)cc(C=C2C(=O)NN(C2=O)c2ccc(F)c(Cl)c2)c1O
Show InChI InChI=1S/C17H11Cl2FN2O4/c1-26-14-6-9(18)4-8(15(14)23)5-11-16(24)21-22(17(11)25)10-2-3-13(20)12(19)7-10/h2-7,23H,1H3,(H,21,24)
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n/an/a 3.80E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336425
PNG
(2-methoxy-4-((2-(naphthalen-2-yl)-5-oxooxazol-4(5H...)
Show SMILES COc1cc(\C=C2\N=C(OC2=O)c2ccc3ccccc3c2)ccc1OC(C)=O
Show InChI InChI=1S/C23H17NO5/c1-14(25)28-20-10-7-15(12-21(20)27-2)11-19-23(26)29-22(24-19)18-9-8-16-5-3-4-6-17(16)13-18/h3-13H,1-2H3/b19-11+
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n/an/a 5.40E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336426
PNG
(2-(4-bromobenzamido)-5-phenylthiophene-3-carboxyli...)
Show SMILES OC(=O)c1cc(sc1NC(=O)c1ccc(Br)cc1)-c1ccccc1
Show InChI InChI=1S/C18H12BrNO3S/c19-13-8-6-12(7-9-13)16(21)20-17-14(18(22)23)10-15(24-17)11-4-2-1-3-5-11/h1-10H,(H,20,21)(H,22,23)
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n/an/a 6.70E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336433
PNG
(1-(4-chlorophenyl)-5-((3-hydroxyphenylamino)methyl...)
Show SMILES Oc1cccc(c1)N=Cc1c(O)n(-c2ccc(Cl)cc2)c(=O)[nH]c1=O
Show InChI InChI=1S/C17H12ClN3O4/c18-10-4-6-12(7-5-10)21-16(24)14(15(23)20-17(21)25)9-19-11-2-1-3-13(22)8-11/h1-9,22,24H,(H,20,23,25)
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n/an/a 8.00E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair
ERO1-like protein alpha


(Homo sapiens)
BDBM50336427
PNG
(3-hydroxy-N'-(1-(3-nitrobenzyl)-2-oxoindolin-3-yli...)
Show SMILES Oc1cc2ccccc2cc1C(=O)N\N=C1/C(=O)N(Cc2cccc(c2)[N+]([O-])=O)c2ccccc12
Show InChI InChI=1S/C26H18N4O5/c31-23-14-18-8-2-1-7-17(18)13-21(23)25(32)28-27-24-20-10-3-4-11-22(20)29(26(24)33)15-16-6-5-9-19(12-16)30(34)35/h1-14,31H,15H2,(H,28,32)/b27-24-
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n/an/a 1.08E+5n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Citation and Details
More data for this
Ligand-Target Pair