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Compile Data Set for Download or QSAR

Found 132 hits Enz. Inhib. hit(s) with Target = 'Elongation of very long chain fatty acids protein 6' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299971
PNG
(4-Fluoro-N-{[(+)-(4S)-2-oxo-6-(1H-pyrazol-5-yl)-4-...)
Show SMILES Fc1ccc(cc1)C(=O)NC[C@]1(OC(=O)Nc2ccc(cc12)-c1cc[nH]n1)C(F)(F)F
Show InChI InChI=1S/C20H14F4N4O3/c21-13-4-1-11(2-5-13)17(29)25-10-19(20(22,23)24)14-9-12(15-7-8-26-28-15)3-6-16(14)27-18(30)31-19/h1-9H,10H2,(H,25,29)(H,26,28)(H,27,30)/t19-/m1/s1
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n/an/a 2.60n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299964
PNG
(4-Fluoro-N-{[2-oxo-6-(1H-pyrazol-5-yl)-4-(trifluor...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-c1cc[nH]n1)C(F)(F)F
Show InChI InChI=1S/C20H14F4N4O3/c21-13-4-1-11(2-5-13)17(29)25-10-19(20(22,23)24)14-9-12(15-7-8-26-28-15)3-6-16(14)27-18(30)31-19/h1-9H,10H2,(H,25,29)(H,26,28)(H,27,30)
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n/an/a 4n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249891
PNG
(3-[2-(4-methyllphenyl)-5-methyl-3-oxo-2,3-dihydro-...)
Show SMILES Cc1[nH]n(-c2ccc(C)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H26F3N3O3/c1-16-10-12-19(13-11-16)34-24(36)22(17(2)32-34)27(28(29,30)31)23-20(14-26(3,4)15-21(23)35)33(25(27)37)18-8-6-5-7-9-18/h5-13,32H,14-15H2,1-4H3
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n/an/a 8.70n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249892
PNG
(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Show SMILES Cc1[nH]n(-c2ccc(OC(F)(F)F)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H23F6N3O4/c1-15-21(23(39)37(35-15)17-9-11-18(12-10-17)41-28(32,33)34)26(27(29,30)31)22-19(13-25(2,3)14-20(22)38)36(24(26)40)16-7-5-4-6-8-16/h4-12,35H,13-14H2,1-3H3
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n/an/a 8.90n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299963
PNG
(4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-4-yl)-4-(trif...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-c1cn[nH]c1)C(F)(F)F
Show InChI InChI=1S/C20H14F4N4O3/c21-14-4-1-11(2-5-14)17(29)25-10-19(20(22,23)24)15-7-12(13-8-26-27-9-13)3-6-16(15)28-18(30)31-19/h1-9H,10H2,(H,25,29)(H,26,27)(H,28,30)
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n/an/a 10n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249844
PNG
(3-[2-(4-isopropylphenyl)-5-methyl-3-oxo-2,3-dihydr...)
Show SMILES CC(C)c1ccc(cc1)-n1[nH]c(C)c(c1=O)C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C30H30F3N3O3/c1-17(2)19-11-13-21(14-12-19)36-26(38)24(18(3)34-36)29(30(31,32)33)25-22(15-28(4,5)16-23(25)37)35(27(29)39)20-9-7-6-8-10-20/h6-14,17,34H,15-16H2,1-5H3
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n/an/a 10n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249791
PNG
(3-[2-(4-chlorophenyl)-5-methyl-3-oxo-2,3-dihydro-1...)
Show SMILES Cc1[nH]n(-c2ccc(Cl)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C27H23ClF3N3O3/c1-15-21(23(36)34(32-15)18-11-9-16(28)10-12-18)26(27(29,30)31)22-19(13-25(2,3)14-20(22)35)33(24(26)37)17-7-5-4-6-8-17/h4-12,32H,13-14H2,1-3H3
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n/an/a 12n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299965
PNG
(4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-1-yl)-4-(trif...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-n1cccn1)C(F)(F)F
Show InChI InChI=1S/C20H14F4N4O3/c21-13-4-2-12(3-5-13)17(29)25-11-19(20(22,23)24)15-10-14(28-9-1-8-26-28)6-7-16(15)27-18(30)31-19/h1-10H,11H2,(H,25,29)(H,27,30)
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n/an/a 13n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249843
PNG
(3-[2-(4-cyanophenyl)-5-methyl-3-oxo-2,3-dihydro-1H...)
Show SMILES Cc1[nH]n(-c2ccc(cc2)C#N)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H23F3N4O3/c1-16-22(24(37)35(33-16)19-11-9-17(15-32)10-12-19)27(28(29,30)31)23-20(13-26(2,3)14-21(23)36)34(25(27)38)18-7-5-4-6-8-18/h4-12,33H,13-14H2,1-3H3
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n/an/a 14n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299948
PNG
(CHEMBL572158 | N-{[(+)-6-Chloro-2-oxo-4-(trifluoro...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(Cl)cc12)C(F)(F)F
Show InChI InChI=1S/C17H11ClF4N2O3/c18-10-3-6-13-12(7-10)16(17(20,21)22,27-15(26)24-13)8-23-14(25)9-1-4-11(19)5-2-9/h1-7H,8H2,(H,23,25)(H,24,26)
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n/an/a 15n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249815
PNG
(3-[2-(4-methoxyphenyl)-5-methyl-3-oxo-2,3-dihydro-...)
Show SMILES COc1ccc(cc1)-n1[nH]c(C)c(c1=O)C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H26F3N3O4/c1-16-22(24(36)34(32-16)18-10-12-19(38-4)13-11-18)27(28(29,30)31)23-20(14-26(2,3)15-21(23)35)33(25(27)37)17-8-6-5-7-9-17/h5-13,32H,14-15H2,1-4H3
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n/an/a 17n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299946
PNG
(1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...)
Show SMILES Fc1ccc(NC(=O)NCC2(OC(=O)Nc3ccc(Cl)cc23)C(F)(F)F)cc1
Show InChI InChI=1S/C17H12ClF4N3O3/c18-9-1-6-13-12(7-9)16(17(20,21)22,28-15(27)25-13)8-23-14(26)24-11-4-2-10(19)3-5-11/h1-7H,8H2,(H,25,27)(H2,23,24,26)
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n/an/a 19n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299963
PNG
(4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-4-yl)-4-(trif...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-c1cn[nH]c1)C(F)(F)F
Show InChI InChI=1S/C20H14F4N4O3/c21-14-4-1-11(2-5-14)17(29)25-10-19(20(22,23)24)15-7-12(13-8-26-27-9-13)3-6-16(15)28-18(30)31-19/h1-9H,10H2,(H,25,29)(H,26,27)(H,28,30)
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n/an/a 22n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299948
PNG
(CHEMBL572158 | N-{[(+)-6-Chloro-2-oxo-4-(trifluoro...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(Cl)cc12)C(F)(F)F
Show InChI InChI=1S/C17H11ClF4N2O3/c18-10-3-6-13-12(7-10)16(17(20,21)22,27-15(26)24-13)8-23-14(25)9-1-4-11(19)5-2-9/h1-7H,8H2,(H,23,25)(H,24,26)
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n/an/a 26n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299965
PNG
(4-Fluoro-N-{[(+)-2-oxo-6-(1H-pyrazol-1-yl)-4-(trif...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-n1cccn1)C(F)(F)F
Show InChI InChI=1S/C20H14F4N4O3/c21-13-4-2-12(3-5-13)17(29)25-11-19(20(22,23)24)15-10-14(28-9-1-8-26-28)6-7-16(15)27-18(30)31-19/h1-10H,11H2,(H,25,29)(H,27,30)
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n/an/a 26n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50293790
PNG
(CHEMBL550828 | N-(4-Isopropylphenyl)-3-endo-(pheny...)
Show SMILES CC(C)c1ccc(NC(=O)N2[C@@H]3CC[C@@H]2CC(C3)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C23H28N2O3S/c1-16(2)17-8-10-18(11-9-17)24-23(26)25-19-12-13-20(25)15-22(14-19)29(27,28)21-6-4-3-5-7-21/h3-11,16,19-20,22H,12-15H2,1-2H3,(H,24,26)/t19-,20-/m1/s1
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n/an/a 32n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris SND1168


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299946
PNG
(1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...)
Show SMILES Fc1ccc(NC(=O)NCC2(OC(=O)Nc3ccc(Cl)cc23)C(F)(F)F)cc1
Show InChI InChI=1S/C17H12ClF4N3O3/c18-9-1-6-13-12(7-9)16(17(20,21)22,28-15(27)25-13)8-23-14(26)24-11-4-2-10(19)3-5-11/h1-7H,8H2,(H,25,27)(H2,23,24,26)
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n/an/a 33n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299951
PNG
(CHEMBL582825 | N-{[6-Chloro-2-oxo-4-(trifluorometh...)
Show SMILES Cc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(Cl)cc12)C(F)(F)F
Show InChI InChI=1S/C18H14ClF3N2O3/c1-10-2-4-11(5-3-10)15(25)23-9-17(18(20,21)22)13-8-12(19)6-7-14(13)24-16(26)27-17/h2-8H,9H2,1H3,(H,23,25)(H,24,26)
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n/an/a 38n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299969
PNG
(4-Fluoro-N-{[2-oxo-6-(2-oxopyrrolidin-1-yl)-4-(tri...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)N1CCCC1=O)C(F)(F)F
Show InChI InChI=1S/C21H17F4N3O4/c22-13-5-3-12(4-6-13)18(30)26-11-20(21(23,24)25)15-10-14(28-9-1-2-17(28)29)7-8-16(15)27-19(31)32-20/h3-8,10H,1-2,9,11H2,(H,26,30)(H,27,31)
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n/an/a 39n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249814
PNG
(3-[2-(3-methoxyphenyl)-5-methyl-3-oxo-2,3-dihydro-...)
Show SMILES COc1cccc(c1)-n1[nH]c(C)c(c1=O)C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H26F3N3O4/c1-16-22(24(36)34(32-16)18-11-8-12-19(13-18)38-4)27(28(29,30)31)23-20(14-26(2,3)15-21(23)35)33(25(27)37)17-9-6-5-7-10-17/h5-13,32H,14-15H2,1-4H3
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n/an/a 43n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249842
PNG
(3-[2-(4-fluorophenyl)-5-methyl-3-oxo-2,3-dihydro-1...)
Show SMILES Cc1[nH]n(-c2ccc(F)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C27H23F4N3O3/c1-15-21(23(36)34(32-15)18-11-9-16(28)10-12-18)26(27(29,30)31)22-19(13-25(2,3)14-20(22)35)33(24(26)37)17-7-5-4-6-8-17/h4-12,32H,13-14H2,1-3H3
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n/an/a 44n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249790
PNG
(3-[2-(3-chlorophenyl)-5-methyl-3-oxo-2,3-dihydro-1...)
Show SMILES Cc1[nH]n(-c2cccc(Cl)c2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C27H23ClF3N3O3/c1-15-21(23(36)34(32-15)18-11-7-8-16(28)12-18)26(27(29,30)31)22-19(13-25(2,3)14-20(22)35)33(24(26)37)17-9-5-4-6-10-17/h4-12,32H,13-14H2,1-3H3
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n/an/a 44n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249813
PNG
(3-[2-(2-methoxyphenyl)-5-methyl-3-oxo-2,3-dihydro-...)
Show SMILES COc1ccccc1-n1[nH]c(C)c(c1=O)C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H26F3N3O4/c1-16-22(24(36)34(32-16)18-12-8-9-13-21(18)38-4)27(28(29,30)31)23-19(14-26(2,3)15-20(23)35)33(25(27)37)17-10-6-5-7-11-17/h5-13,32H,14-15H2,1-4H3
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n/an/a 58n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298994
PNG
((1R*,4S*,6R*)-(+/-)-N-[4-(Propan-2-yloxy)phenyl]-2...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2ccsc2)cc1
Show InChI InChI=1S/C21H26N2O4S2/c1-14(2)27-17-6-4-16(5-7-17)22-21(24)19-11-15-3-8-20(19)23(12-15)29(25,26)18-9-10-28-13-18/h4-7,9-10,13-15,19-20H,3,8,11-12H2,1-2H3,(H,22,24)/t15-,19+,20-/m0/s1
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n/an/a 67n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299970
PNG
(4-Fluoro-N-{[2-oxo-6-(2-oxo-1,3-oxazolidin-3-yl)-4...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)N1CCOC1=O)C(F)(F)F
Show InChI InChI=1S/C20H15F4N3O5/c21-12-3-1-11(2-4-12)16(28)25-10-19(20(22,23)24)14-9-13(27-7-8-31-18(27)30)5-6-15(14)26-17(29)32-19/h1-6,9H,7-8,10H2,(H,25,28)(H,26,29)
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n/an/a 67n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298985
PNG
((1R*,4S*,6R*)-(+/-)-2-(Phenylsulfonyl)-N-[4-(propa...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C23H28N2O4S/c1-16(2)29-19-11-9-18(10-12-19)24-23(26)21-14-17-8-13-22(21)25(15-17)30(27,28)20-6-4-3-5-7-20/h3-7,9-12,16-17,21-22H,8,13-15H2,1-2H3,(H,24,26)/t17-,21+,22-/m0/s1
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n/an/a 70n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50378036
PNG
(CHEMBL1163008)
Show SMILES CC(=Nc1ccc(cc1)C(C)(C)C)N1C2CCC1CC(C2)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H32N2O2S/c1-18(26-20-12-10-19(11-13-20)25(2,3)4)27-21-14-15-22(27)17-24(16-21)30(28,29)23-8-6-5-7-9-23/h5-13,21-22,24H,14-17H2,1-4H3
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n/an/a 78n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris SND1168


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50293789
PNG
(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2[C@@H]3CC[C@@H]2CC(C3)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C20H20F3N3O3S/c21-20(22,23)13-4-6-14(7-5-13)25-19(27)26-15-8-9-16(26)12-17(11-15)30(28,29)18-3-1-2-10-24-18/h1-7,10,15-17H,8-9,11-12H2,(H,25,27)/t15-,16-/m1/s1
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n/an/a 79n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris SND1168


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298967
PNG
((1R*,4S*,6R*)-(+/-)-N-[4-(Propan-2-yloxy)phenyl]-2...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2cccnc2)cc1
Show InChI InChI=1S/C22H27N3O4S/c1-15(2)29-18-8-6-17(7-9-18)24-22(26)20-12-16-5-10-21(20)25(14-16)30(27,28)19-4-3-11-23-13-19/h3-4,6-9,11,13,15-16,20-21H,5,10,12,14H2,1-2H3,(H,24,26)/t16-,20+,21-/m0/s1
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n/an/a 80n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299959
PNG
(4-Fluoro-N-{[2-oxo-4-(trifluoromethyl)-1,4-dihydro...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccccc12)C(F)(F)F
Show InChI InChI=1S/C17H12F4N2O3/c18-11-7-5-10(6-8-11)14(24)22-9-16(17(19,20)21)12-3-1-2-4-13(12)23-15(25)26-16/h1-8H,9H2,(H,22,24)(H,23,25)
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n/an/a 95n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299966
PNG
(4-Fluoro-N-{[2-oxo-6-(1H-1,2,4-triazol-5-yl)-4-(tr...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-c1nnc[nH]1)C(F)(F)F
Show InChI InChI=1S/C19H13F4N5O3/c20-12-4-1-10(2-5-12)16(29)24-8-18(19(21,22)23)13-7-11(15-25-9-26-28-15)3-6-14(13)27-17(30)31-18/h1-7,9H,8H2,(H,24,29)(H,27,30)(H,25,26,28)
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n/an/a 97n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249713
PNG
(3-(5-ethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4...)
Show SMILES CCc1[nH]n(-c2ccccc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H26F3N3O3/c1-4-19-22(24(36)34(32-19)18-13-9-6-10-14-18)27(28(29,30)31)23-20(15-26(2,3)16-21(23)35)33(25(27)37)17-11-7-5-8-12-17/h5-14,32H,4,15-16H2,1-3H3
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n/an/a 99n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299961
PNG
(4-Fluoro-N-{[2-oxo-6-(2-oxopyridin-1(2H)-yl)-4-(tr...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-n1ccccc1=O)C(F)(F)F
Show InChI InChI=1S/C22H15F4N3O4/c23-14-6-4-13(5-7-14)19(31)27-12-21(22(24,25)26)16-11-15(29-10-2-1-3-18(29)30)8-9-17(16)28-20(32)33-21/h1-11H,12H2,(H,27,31)(H,28,32)
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n/an/a 106n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298991
PNG
((1R*,4S*,6R*)-(+/-)-2-[(3-Fluorophenyl)sulfonyl]-N...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2cccc(F)c2)cc1
Show InChI InChI=1S/C23H27FN2O4S/c1-15(2)30-19-9-7-18(8-10-19)25-23(27)21-12-16-6-11-22(21)26(14-16)31(28,29)20-5-3-4-17(24)13-20/h3-5,7-10,13,15-16,21-22H,6,11-12,14H2,1-2H3,(H,25,27)/t16-,21+,22-/m0/s1
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n/an/a 110n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298971
PNG
((1R*,4S*,6R*)-(+/-)-2-(Butylsulfonyl)-N-[4-(propan...)
Show SMILES CCCCS(=O)(=O)N1C[C@H]2CC[C@H]1[C@@H](C2)C(=O)Nc1ccc(OC(C)C)cc1
Show InChI InChI=1S/C21H32N2O4S/c1-4-5-12-28(25,26)23-14-16-6-11-20(23)19(13-16)21(24)22-17-7-9-18(10-8-17)27-15(2)3/h7-10,15-16,19-20H,4-6,11-14H2,1-3H3,(H,22,24)/t16-,19+,20-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298969
PNG
((1R*,4S*,6R*)-(+/-)-N-[4-(Propan-2-yloxy)phenyl]-2...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C22H27N3O4S/c1-15(2)29-18-9-7-17(8-10-18)24-22(26)19-13-16-6-11-20(19)25(14-16)30(27,28)21-5-3-4-12-23-21/h3-5,7-10,12,15-16,19-20H,6,11,13-14H2,1-2H3,(H,24,26)/t16-,19+,20-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299962
PNG
(4-Fluoro-N-{[6-(isoxazol-4-yl)-2-oxo-4-(trifluorom...)
Show SMILES Fc1ccc(cc1)C(=O)NCC1(OC(=O)Nc2ccc(cc12)-c1ccon1)C(F)(F)F
Show InChI InChI=1S/C20H13F4N3O4/c21-13-4-1-11(2-5-13)17(28)25-10-19(20(22,23)24)14-9-12(15-7-8-30-27-15)3-6-16(14)26-18(29)31-19/h1-9H,10H2,(H,25,28)(H,26,29)
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n/an/a 121n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249764
PNG
(3'-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol...)
Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC1(CCC1)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C28H24F3N3O3/c1-17-22(24(36)34(32-17)19-11-6-3-7-12-19)27(28(29,30)31)23-20(15-26(13-8-14-26)16-21(23)35)33(25(27)37)18-9-4-2-5-10-18/h2-7,9-12,32H,8,13-16H2,1H3
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n/an/a 123n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298992
PNG
((1R*,4S*,6R*)-(+/-)-2-[(2-Fluorophenyl)sulfonyl]-N...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2ccccc2F)cc1
Show InChI InChI=1S/C23H27FN2O4S/c1-15(2)30-18-10-8-17(9-11-18)25-23(27)19-13-16-7-12-21(19)26(14-16)31(28,29)22-6-4-3-5-20(22)24/h3-6,8-11,15-16,19,21H,7,12-14H2,1-2H3,(H,25,27)/t16-,19+,21-/m0/s1
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n/an/a 130n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50299940
PNG
(CHEMBL578605 | [6-Chloro-2-oxo-4-(trifluoromethyl)...)
Show SMILES Fc1ccc(NC(=O)OCC2(OC(=O)Nc3ccc(Cl)cc23)C(F)(F)F)cc1
Show InChI InChI=1S/C17H11ClF4N2O4/c18-9-1-6-13-12(7-9)16(17(20,21)22,28-15(26)24-13)8-27-14(25)23-11-4-2-10(19)3-5-11/h1-7H,8H2,(H,23,25)(H,24,26)
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n/an/a 142n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249562
PNG
(1-cyclopropyl-6,6-dimethyl-3-(5-methyl-3-oxo-2-phe...)
Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C1(C(=O)N(C2CC2)C2=C1C(=O)CC(C)(C)C2)C(F)(F)F
Show InChI InChI=1S/C24H24F3N3O3/c1-13-18(20(32)30(28-13)15-7-5-4-6-8-15)23(24(25,26)27)19-16(11-22(2,3)12-17(19)31)29(21(23)33)14-9-10-14/h4-8,14,28H,9-12H2,1-3H3
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n/an/a 144n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249560
PNG
(6,6-dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydr...)
Show SMILES CCCN1C2=C(C(=O)CC(C)(C)C2)C(C1=O)(c1c(C)[nH]n(-c2ccccc2)c1=O)C(F)(F)F
Show InChI InChI=1S/C24H26F3N3O3/c1-5-11-29-16-12-22(3,4)13-17(31)19(16)23(21(29)33,24(25,26)27)18-14(2)28-30(20(18)32)15-9-7-6-8-10-15/h6-10,28H,5,11-13H2,1-4H3
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n/an/a 185n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298990
PNG
((1R*,4S*,6R*)-(+/-)-2-[(4-Fluorophenyl)sulfonyl]-N...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C23H27FN2O4S/c1-15(2)30-19-8-6-18(7-9-19)25-23(27)21-13-16-3-12-22(21)26(14-16)31(28,29)20-10-4-17(24)5-11-20/h4-11,15-16,21-22H,3,12-14H2,1-2H3,(H,25,27)/t16-,21+,22-/m0/s1
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n/an/a 190n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249893
PNG
(6,6-dimethyl-3-[5-methyl-3-oxo-2-(4-phenoxyphenyl)...)
Show SMILES Cc1[nH]n(-c2ccc(Oc3ccccc3)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C33H28F3N3O4/c1-20-27(29(41)39(37-20)22-14-16-24(17-15-22)43-23-12-8-5-9-13-23)32(33(34,35)36)28-25(18-31(2,3)19-26(28)40)38(30(32)42)21-10-6-4-7-11-21/h4-17,37H,18-19H2,1-3H3
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n/an/a 196n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249641
PNG
(1-cyclohexyl-6,6-dimethyl-3-(5-methyl-3-oxo-2-phen...)
Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C1(C(=O)N(C2CCCCC2)C2=C1C(=O)CC(C)(C)C2)C(F)(F)F
Show InChI InChI=1S/C27H30F3N3O3/c1-16-21(23(35)33(31-16)18-12-8-5-9-13-18)26(27(28,29)30)22-19(14-25(2,3)15-20(22)34)32(24(26)36)17-10-6-4-7-11-17/h5,8-9,12-13,17,31H,4,6-7,10-11,14-15H2,1-3H3
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n/an/a 210n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298983
PNG
((1R*,4S*,6R*)-(+/-)-N-[4-(Propan-2-yloxy)phenyl]-2...)
Show SMILES CCCS(=O)(=O)N1C[C@H]2CC[C@H]1[C@@H](C2)C(=O)Nc1ccc(OC(C)C)cc1
Show InChI InChI=1S/C20H30N2O4S/c1-4-11-27(24,25)22-13-15-5-10-19(22)18(12-15)20(23)21-16-6-8-17(9-7-16)26-14(2)3/h6-9,14-15,18-19H,4-5,10-13H2,1-3H3,(H,21,23)/t15-,18+,19-/m0/s1
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n/an/a 210n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298968
PNG
((1R*,4S*,6R*)-(+/-)-2-[(1-Methyl-1H-imidazol-4-yl)...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2cn(C)cn2)cc1
Show InChI InChI=1S/C21H28N4O4S/c1-14(2)29-17-7-5-16(6-8-17)23-21(26)18-10-15-4-9-19(18)25(11-15)30(27,28)20-12-24(3)13-22-20/h5-8,12-15,18-19H,4,9-11H2,1-3H3,(H,23,26)/t15-,18+,19-/m0/s1
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n/an/a 220n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249665
PNG
(1-(3-methoxyphenyl)-6,6-dimethyl-3-(5-methyl-3-oxo...)
Show SMILES COc1cccc(c1)N1C2=C(C(=O)CC(C)(C)C2)C(C1=O)(c1c(C)[nH]n(-c2ccccc2)c1=O)C(F)(F)F
Show InChI InChI=1S/C28H26F3N3O4/c1-16-22(24(36)34(32-16)17-9-6-5-7-10-17)27(28(29,30)31)23-20(14-26(2,3)15-21(23)35)33(25(27)37)18-11-8-12-19(13-18)38-4/h5-13,32H,14-15H2,1-4H3
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n/an/a 226n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50298968
PNG
((1R*,4S*,6R*)-(+/-)-2-[(1-Methyl-1H-imidazol-4-yl)...)
Show SMILES CC(C)Oc1ccc(NC(=O)[C@@H]2C[C@@H]3CC[C@@H]2N(C3)S(=O)(=O)c2cn(C)cn2)cc1
Show InChI InChI=1S/C21H28N4O4S/c1-14(2)29-17-7-5-16(6-8-17)23-21(26)18-10-15-4-9-19(18)25(11-15)30(27,28)20-12-24(3)13-22-20/h5-8,12-15,18-19H,4,9-11H2,1-3H3,(H,23,26)/t15-,18+,19-/m0/s1
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n/an/a 230n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of C-terminal V5-epitope-tagged human ELOVL6 expressed in african green monkey COS7 cells


Citation and Details
More data for this
Ligand-Target Pair
Elongation of very long chain fatty acids protein 6


(Homo sapiens)
BDBM50249711
PNG
(1-(3-chlorophenyl)-6,6-dimethyl-3-(5-methyl-3-oxo-...)
Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1cccc(Cl)c1)C(F)(F)F
Show InChI InChI=1S/C27H23ClF3N3O3/c1-15-21(23(36)34(32-15)17-9-5-4-6-10-17)26(27(29,30)31)22-19(13-25(2,3)14-20(22)35)33(24(26)37)18-11-7-8-16(28)12-18/h4-12,32H,13-14H2,1-3H3
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n/an/a 245n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongation


Citation and Details
More data for this
Ligand-Target Pair
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