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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase (EL)' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase (EL)


(Rattus norvegicus (Rat))
BDBM141542
PNG
(US8921404, 8)
Show SMILES CCCCCCNC(=O)Nc1noc2ccccc12
Show InChI InChI=1S/C14H19N3O2/c1-2-3-4-7-10-15-14(18)16-13-11-8-5-6-9-12(11)19-17-13/h5-6,8-9H,2-4,7,10H2,1H3,(H2,15,16,17,18)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.46E+4n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The phospholipase-specific substrate 1,2-bis(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-undecanoyl)-sn-glycero-3-phosphocholine, (manu...


US Patent US8921404 (2014)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Rattus norvegicus (Rat))
BDBM141541
PNG
(US8921404, 7)
Show SMILES Cc1ccccc1CNC(=O)Nc1nsc2ccc(cc12)[N+]([O-])=O
Show InChI InChI=1S/C16H14N4O3S/c1-10-4-2-3-5-11(10)9-17-16(21)18-15-13-8-12(20(22)23)6-7-14(13)24-19-15/h2-8H,9H2,1H3,(H2,17,18,19,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 1.46E+4n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The phospholipase-specific substrate 1,2-bis(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-undecanoyl)-sn-glycero-3-phosphocholine, (manu...


US Patent US8921404 (2014)

More data for this
Ligand-Target Pair