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Compile Data Set for Download or QSAR

Found 745 hits Enz. Inhib. hit(s) with Target = 'Endothelial lipase (EL)' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151267
PNG
(US8987314, B63)
Show SMILES COCc1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C20H23N3O6S3/c1-29-12-13-3-5-14(6-4-13)15-7-8-16-17(11-15)30-20(23-16)18(31(2,25)26)19(24)22-9-10-32(21,27)28/h3-8,11,18H,9-10,12H2,1-2H3,(H,22,24)(H2,21,27,28)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151268
PNG
(US8987314, B64)
Show SMILES COCCOC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C22H26N4O8S3/c1-33-10-11-34-22(28)25-16-6-3-14(4-7-16)15-5-8-17-18(13-15)35-21(26-17)19(36(2,29)30)20(27)24-9-12-37(23,31)32/h3-8,13,19H,9-12H2,1-2H3,(H,24,27)(H,25,28)(H2,23,31,32)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151568
PNG
(US8987314, B379)
Show SMILES CC(=O)Nc1cccc(c1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C20H22N4O6S3/c1-12(25)23-15-5-3-4-13(10-15)14-6-7-17-16(11-14)24-20(31-17)18(32(2,27)28)19(26)22-8-9-33(21,29)30/h3-7,10-11,18H,8-9H2,1-2H3,(H,22,26)(H,23,25)(H2,21,29,30)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151498
PNG
(US8987314, B309)
Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2cc(ccc2s1)-c1ccc(F)nc1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C24H20F4N4O6S3/c25-20-8-4-16(12-31-20)15-3-7-19-18(11-15)32-23(39-19)21(22(33)30-9-10-41(29,36)37)40(34,35)13-14-1-5-17(6-2-14)38-24(26,27)28/h1-8,11-12,21H,9-10,13H2,(H,30,33)(H2,29,36,37)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151416
PNG
(US8987314, B227)
Show SMILES NC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C26H23F3N4O7S3/c27-26(28,29)40-19-8-1-15(2-9-19)14-42(36,37)22(24(35)32-11-12-43(31,38)39)25-33-20-10-7-18(13-21(20)41-25)16-3-5-17(6-4-16)23(30)34/h1-10,13,22H,11-12,14H2,(H2,30,34)(H,32,35)(H2,31,38,39)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151415
PNG
(US8987314, B226)
Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccc(cc1)C(=O)NC1CC1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C29H27F3N4O7S3/c30-29(31,32)43-22-10-1-17(2-11-22)16-45(39,40)25(27(38)34-13-14-46(33,41)42)28-36-23-12-7-20(15-24(23)44-28)18-3-5-19(6-4-18)26(37)35-21-8-9-21/h1-7,10-12,15,21,25H,8-9,13-14,16H2,(H,34,38)(H,35,37)(H2,33,41,42)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151387
PNG
(US8987314, B193)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccnc(O)c1F
Show InChI InChI=1/C17H17FN4O6S3/c1-30(25,26)14(16(24)21-6-7-31(19,27)28)17-22-11-3-2-9(8-12(11)29-17)10-4-5-20-15(23)13(10)18/h2-5,8,14H,6-7H2,1H3,(H,20,23)(H,21,24)(H2,19,27,28)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151297
PNG
(US8987314, B93)
Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C22H26N4O7S3/c1-33-11-9-24-20(27)15-5-3-14(4-6-15)16-7-8-18-17(13-16)26-22(34-18)19(35(2,29)30)21(28)25-10-12-36(23,31)32/h3-8,13,19H,9-12H2,1-2H3,(H,24,27)(H,25,28)(H2,23,31,32)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151292
PNG
(US8987314, B88)
Show SMILES COc1cc(ccn1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C18H20N4O6S3/c1-28-15-10-12(5-6-20-15)11-3-4-14-13(9-11)22-18(29-14)16(30(2,24)25)17(23)21-7-8-31(19,26)27/h3-6,9-10,16H,7-8H2,1-2H3,(H,21,23)(H2,19,26,27)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151291
PNG
(US8987314, B87)
Show SMILES COc1ccc(cn1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C18H20N4O6S3/c1-28-15-6-4-12(10-21-15)11-3-5-14-13(9-11)22-18(29-14)16(30(2,24)25)17(23)20-7-8-31(19,26)27/h3-6,9-10,16H,7-8H2,1-2H3,(H,20,23)(H2,19,26,27)
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n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151399
PNG
(US8987314, B210)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(Oc2ccccc2)c1
Show InChI InChI=1/C24H23N3O6S3/c1-35(29,30)22(23(28)26-12-13-36(25,31)32)24-27-20-11-10-17(15-21(20)34-24)16-6-5-9-19(14-16)33-18-7-3-2-4-8-18/h2-11,14-15,22H,12-13H2,1H3,(H,26,28)(H2,25,31,32)
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n/an/a 0.600n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151510
PNG
(US8987314, B321)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccc(cc1)C(=O)N1CC(F)(F)C1
Show InChI InChI=1/C22H22F2N4O6S3/c1-36(31,32)18(19(29)26-8-9-37(25,33)34)20-27-16-10-15(6-7-17(16)35-20)13-2-4-14(5-3-13)21(30)28-11-22(23,24)12-28/h2-7,10,18H,8-9,11-12H2,1H3,(H,26,29)(H2,25,33,34)
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n/an/a 0.600n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151400
PNG
(US8987314, B211)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(cc1)C(=O)NCCCO
Show InChI InChI=1/C22H26N4O7S3/c1-35(30,31)19(21(29)25-10-12-36(23,32)33)22-26-17-8-7-16(13-18(17)34-22)14-3-5-15(6-4-14)20(28)24-9-2-11-27/h3-8,13,19,27H,2,9-12H2,1H3,(H,24,28)(H,25,29)(H2,23,32,33)
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151493
PNG
(US8987314, B304)
Show SMILES CO[C@H]1CCN(C1)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F
Show InChI InChI=1/C26H29F3N4O7S3/c1-40-19-8-11-33(15-19)25(35)17-4-2-16(3-5-17)18-6-7-20-21(14-18)41-24(32-20)22(23(34)31-10-13-43(30,38)39)42(36,37)12-9-26(27,28)29/h2-7,14,19,22H,8-13,15H2,1H3,(H,31,34)(H2,30,38,39)/t19-,22?/s2
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151572
PNG
(US8987314, B383)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1cccnc1F
Show InChI InChI=1/C17H17FN4O5S3/c1-29(24,25)14(16(23)21-7-8-30(19,26)27)17-22-12-9-10(4-5-13(12)28-17)11-3-2-6-20-15(11)18/h2-6,9,14H,7-8H2,1H3,(H,21,23)(H2,19,26,27)
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151567
PNG
(US8987314, B378)
Show SMILES COCc1ccc(cc1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C20H23N3O6S3/c1-29-12-13-3-5-14(6-4-13)15-7-8-17-16(11-15)23-20(30-17)18(31(2,25)26)19(24)22-9-10-32(21,27)28/h3-8,11,18H,9-10,12H2,1-2H3,(H,22,24)(H2,21,27,28)
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151315
PNG
(BDBM151471 | US8987314, B113)
Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C29H29F3N4O8S3/c1-43-14-12-34-26(37)20-6-4-19(5-7-20)21-8-11-23-24(16-21)45-28(36-23)25(27(38)35-13-15-47(33,41)42)46(39,40)17-18-2-9-22(10-3-18)44-29(30,31)32/h2-11,16,25H,12-15,17H2,1H3,(H,34,37)(H,35,38)(H2,33,41,42)
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151519
PNG
(US8987314, B330)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(cc1)C(=O)N1CC(F)C1
Show InChI InChI=1/C22H23FN4O6S3/c1-35(30,31)19(20(28)25-8-9-36(24,32)33)21-26-17-7-6-15(10-18(17)34-21)13-2-4-14(5-3-13)22(29)27-11-16(23)12-27/h2-7,10,16,19H,8-9,11-12H2,1H3,(H,25,28)(H2,24,32,33)
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151480
PNG
(US8987314, B291)
Show SMILES COCCN(C)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC1CC1
Show InChI InChI=1/C26H32N4O7S3/c1-30(12-13-37-2)26(32)19-7-5-18(6-8-19)20-9-10-21-22(15-20)38-25(29-21)23(39(33,34)16-17-3-4-17)24(31)28-11-14-40(27,35)36/h5-10,15,17,23H,3-4,11-14,16H2,1-2H3,(H,28,31)(H2,27,35,36)
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n/an/a 0.700n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151541
PNG
(US8987314, B352)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccccc1F
Show InChI InChI=1/C18H18FN3O5S3/c1-29(24,25)16(17(23)21-8-9-30(20,26)27)18-22-14-10-11(6-7-15(14)28-18)12-4-2-3-5-13(12)19/h2-7,10,16H,8-9H2,1H3,(H,21,23)(H2,20,26,27)
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n/an/a 0.800n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151397
PNG
(US8987314, B208)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(Cl)c1
Show InChI InChI=1/C18H18ClN3O5S3/c1-29(24,25)16(17(23)21-7-8-30(20,26)27)18-22-14-6-5-12(10-15(14)28-18)11-3-2-4-13(19)9-11/h2-6,9-10,16H,7-8H2,1H3,(H,21,23)(H2,20,26,27)
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n/an/a 0.800n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151563
PNG
(US8987314, B374)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ncccn1
Show InChI InChI=1/C16H17N5O5S3/c1-28(23,24)13(15(22)20-7-8-29(17,25)26)16-21-11-9-10(3-4-12(11)27-16)14-18-5-2-6-19-14/h2-6,9,13H,7-8H2,1H3,(H,20,22)(H2,17,25,26)
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n/an/a 0.800n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151316
PNG
(US8987314, B114)
Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC1CC1
Show InChI InChI=1/C25H30N4O7S3/c1-36-12-10-27-23(30)18-6-4-17(5-7-18)19-8-9-20-21(14-19)37-25(29-20)22(38(32,33)15-16-2-3-16)24(31)28-11-13-39(26,34)35/h4-9,14,16,22H,2-3,10-13,15H2,1H3,(H,27,30)(H,28,31)(H2,26,34,35)
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n/an/a 0.800n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151477
PNG
(US8987314, B288)
Show SMILES COCCN(C)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(cc1)C(F)(F)F
Show InChI InChI=1/C30H31F3N4O7S3/c1-37(14-15-44-2)29(39)21-7-5-20(6-8-21)22-9-12-24-25(17-22)45-28(36-24)26(27(38)35-13-16-47(34,42)43)46(40,41)18-19-3-10-23(11-4-19)30(31,32)33/h3-12,17,26H,13-16,18H2,1-2H3,(H,35,38)(H2,34,42,43)
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n/an/a 0.800n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151259
PNG
(BDBM151425 | US8987314, B55)
Show SMILES CC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F
Show InChI InChI=1/C22H23F3N4O6S3/c1-13(30)28-16-5-2-14(3-6-16)15-4-7-17-18(12-15)36-21(29-17)19(20(31)27-9-11-38(26,34)35)37(32,33)10-8-22(23,24)25/h2-7,12,19H,8-11H2,1H3,(H,27,31)(H,28,30)(H2,26,34,35)
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n/an/a 0.800n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151433
PNG
(US8987314, B244)
Show SMILES COC(C)(C)CNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CC1CC1
Show InChI InChI=1/C27H34N4O7S3/c1-27(2,38-3)16-30-24(32)19-8-6-18(7-9-19)20-10-11-21-22(14-20)39-26(31-21)23(40(34,35)15-17-4-5-17)25(33)29-12-13-41(28,36)37/h6-11,14,17,23H,4-5,12-13,15-16H2,1-3H3,(H,29,33)(H,30,32)(H2,28,36,37)
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n/an/a 0.900n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151389
PNG
(US8987314, B195)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccc(O)nc1
Show InChI InChI=1/C17H18N4O6S3/c1-29(24,25)15(16(23)19-6-7-30(18,26)27)17-21-12-8-10(2-4-13(12)28-17)11-3-5-14(22)20-9-11/h2-5,8-9,15H,6-7H2,1H3,(H,19,23)(H,20,22)(H2,18,26,27)
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n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151534
PNG
(US8987314, B345)
Show SMILES CC(C)(O)CNC(=O)c1cccc(c1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F
Show InChI InChI=1/C25H29F3N4O7S3/c1-24(2,35)14-31-21(33)17-5-3-4-15(12-17)16-6-7-18-19(13-16)40-23(32-18)20(22(34)30-9-11-42(29,38)39)41(36,37)10-8-25(26,27)28/h3-7,12-13,20,35H,8-11,14H2,1-2H3,(H,30,34)(H,31,33)(H2,29,38,39)
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n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151537
PNG
(US8987314, B348)
Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(=O)N1CCCCC1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1/C31H34N4O6S3/c1-21-18-26-27(19-25(21)23-10-12-24(13-11-23)31(37)35-15-6-3-7-16-35)42-30(34-26)28(29(36)33-14-17-44(32,40)41)43(38,39)20-22-8-4-2-5-9-22/h2,4-5,8-13,18-19,28H,3,6-7,14-17,20H2,1H3,(H,33,36)(H2,32,40,41)
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n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151499
PNG
(US8987314, B310)
Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2cc(ccc2s1)-c1ccc(F)nc1)S(=O)(=O)Cc1ccc(F)cc1
Show InChI InChI=1/C23H20F2N4O5S3/c24-17-5-1-14(2-6-17)13-36(31,32)21(22(30)27-9-10-37(26,33)34)23-29-18-11-15(3-7-19(18)35-23)16-4-8-20(25)28-12-16/h1-8,11-12,21H,9-10,13H2,(H,27,30)(H2,26,33,34)
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n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151381
PNG
(US8987314, B186)
Show SMILES CC(C)(O)Cn1cc(ccc1=O)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C21H26N4O7S3/c1-21(2,28)12-25-11-14(5-7-17(25)26)13-4-6-15-16(10-13)33-20(24-15)18(34(3,29)30)19(27)23-8-9-35(22,31)32/h4-7,10-11,18,28H,8-9,12H2,1-3H3,(H,23,27)(H2,22,31,32)
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n/an/a 1.10n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151570
PNG
(US8987314, B381)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccncc1F
Show InChI InChI=1/C17H17FN4O5S3/c1-29(24,25)15(16(23)21-6-7-30(19,26)27)17-22-13-8-10(2-3-14(13)28-17)11-4-5-20-9-12(11)18/h2-5,8-9,15H,6-7H2,1H3,(H,21,23)(H2,19,26,27)
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n/an/a 1.10n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151465
PNG
(US8987314, B276)
Show SMILES CC(C)(C)OC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1/C29H31N3O7S3/c1-29(2,3)39-28(34)21-11-9-20(10-12-21)22-13-14-23-24(17-22)40-27(32-23)25(26(33)31-15-16-42(30,37)38)41(35,36)18-19-7-5-4-6-8-19/h4-14,17,25H,15-16,18H2,1-3H3,(H,31,33)(H2,30,37,38)
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n/an/a 1.10n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151317
PNG
(US8987314, B115)
Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1cccc(c1)C#N
Show InChI InChI=1/C29H29N5O7S3/c1-41-13-11-32-27(35)22-7-5-21(6-8-22)23-9-10-24-25(16-23)42-29(34-24)26(28(36)33-12-14-44(31,39)40)43(37,38)18-20-4-2-3-19(15-20)17-30/h2-10,15-16,26H,11-14,18H2,1H3,(H,32,35)(H,33,36)(H2,31,39,40)
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n/an/a 1.20n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151266
PNG
(US8987314, B62)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)N1CCCC1
Show InChI InChI=1/C22H26N4O5S3/c1-33(28,29)20(21(27)24-9-12-34(23,30)31)22-25-18-8-7-16(14-19(18)32-22)15-5-4-6-17(13-15)26-10-2-3-11-26/h4-8,13-14,20H,2-3,9-12H2,1H3,(H,24,27)(H2,23,30,31)
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n/an/a 1.20n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151412
PNG
(US8987314, B223)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(cc1)-c1nnc(N)s1
Show InChI InChI=1/C20H20N6O5S4/c1-34(28,29)16(17(27)23-8-9-35(22,30)31)19-24-14-7-6-13(10-15(14)32-19)11-2-4-12(5-3-11)18-25-26-20(21)33-18/h2-7,10,16H,8-9H2,1H3,(H2,21,26)(H,23,27)(H2,22,30,31)
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n/an/a 1.20n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151401
PNG
(US8987314, B212)
Show SMILES CN(C)C(=O)c1ccc(cc1F)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C21H23FN4O6S3/c1-26(2)21(28)14-6-4-12(10-15(14)22)13-5-7-16-17(11-13)33-20(25-16)18(34(3,29)30)19(27)24-8-9-35(23,31)32/h4-7,10-11,18H,8-9H2,1-3H3,(H,24,27)(H2,23,31,32)
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n/an/a 1.20n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151514
PNG
(US8987314, B325)
Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(O)=O)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1/C26H25N3O7S3/c1-16-13-21-22(14-20(16)18-7-9-19(10-8-18)26(31)32)37-25(29-21)23(24(30)28-11-12-39(27,35)36)38(33,34)15-17-5-3-2-4-6-17/h2-10,13-14,23H,11-12,15H2,1H3,(H,28,30)(H,31,32)(H2,27,35,36)
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n/an/a 1.20n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151497
PNG
(US8987314, B308)
Show SMILES COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccc(F)nc1
Show InChI InChI=1/C19H21FN4O6S3/c1-30-7-9-32(26,27)17(18(25)22-6-8-33(21,28)29)19-24-14-10-12(2-4-15(14)31-19)13-3-5-16(20)23-11-13/h2-5,10-11,17H,6-9H2,1H3,(H,22,25)(H2,21,28,29)
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n/an/a 1.30n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151462
PNG
(US8987314, B273)
Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(=O)OC(C)(C)C)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1/C30H33N3O7S3/c1-19-16-24-25(17-23(19)21-10-12-22(13-11-21)29(35)40-30(2,3)4)41-28(33-24)26(27(34)32-14-15-43(31,38)39)42(36,37)18-20-8-6-5-7-9-20/h5-13,16-17,26H,14-15,18H2,1-4H3,(H,32,34)(H2,31,38,39)
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n/an/a 1.40n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151396
PNG
(US8987314, B207)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(Cl)cc1
Show InChI InChI=1/C18H18ClN3O5S3/c1-29(24,25)16(17(23)21-8-9-30(20,26)27)18-22-14-7-4-12(10-15(14)28-18)11-2-5-13(19)6-3-11/h2-7,10,16H,8-9H2,1H3,(H,21,23)(H2,20,26,27)
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n/an/a 1.40n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151299
PNG
(BDBM151558 | US8987314, B95)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccnc(F)c1
Show InChI InChI=1/C17H17FN4O5S3/c1-29(24,25)15(16(23)21-6-7-30(19,26)27)17-22-12-8-10(2-3-13(12)28-17)11-4-5-20-14(18)9-11/h2-5,8-9,15H,6-7H2,1H3,(H,21,23)(H2,19,26,27)
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n/an/a 1.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151521
PNG
(US8987314, B332)
Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1cccc(c1)C(=O)N1CCC(O)CC1)S(=O)(=O)CCC(F)(F)F
Show InChI InChI=1/C26H29F3N4O7S3/c27-26(28,29)8-12-42(37,38)22(23(35)31-9-13-43(30,39)40)24-32-20-5-4-17(15-21(20)41-24)16-2-1-3-18(14-16)25(36)33-10-6-19(34)7-11-33/h1-5,14-15,19,22,34H,6-13H2,(H,31,35)(H2,30,39,40)
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n/an/a 1.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM205048
PNG
(US9249096, 65)
Show SMILES CC(C)OCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O
Show InChI InChI=1S/C19H24Cl2N2O4/c1-12(2)27-9-8-23-11-14(17(24)19(23)26)18(25)22-7-3-4-13-5-6-15(20)16(21)10-13/h5-6,10,12,24H,3-4,7-9,11H2,1-2H3,(H,22,25)
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n/an/a 1.60n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 uL of assay buffer (50 mM HEPES pH 8.0, 50 mM N...


US Patent US9249096 (2016)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151515
PNG
(US8987314, B326)
Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(O)=O)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C20H21N3O7S3/c1-11-9-15-16(10-14(11)12-3-5-13(6-4-12)20(25)26)31-19(23-15)17(32(2,27)28)18(24)22-7-8-33(21,29)30/h3-6,9-10,17H,7-8H2,1-2H3,(H,22,24)(H,25,26)(H2,21,29,30)
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n/an/a 1.60n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151403
PNG
(US8987314, B214)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(cc1)C(N)=O
Show InChI InChI=1/C19H20N4O6S3/c1-31(26,27)16(18(25)22-8-9-32(21,28)29)19-23-14-7-6-13(10-15(14)30-19)11-2-4-12(5-3-11)17(20)24/h2-7,10,16H,8-9H2,1H3,(H2,20,24)(H,22,25)(H2,21,28,29)
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n/an/a 1.60n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151463
PNG
(US8987314, B274)
Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(=O)OC(C)(C)C)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C24H29N3O7S3/c1-14-12-18-19(13-17(14)15-6-8-16(9-7-15)23(29)34-24(2,3)4)35-22(27-18)20(36(5,30)31)21(28)26-10-11-37(25,32)33/h6-9,12-13,20H,10-11H2,1-5H3,(H,26,28)(H2,25,32,33)
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n/an/a 1.70n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151407
PNG
(US8987314, B218)
Show SMILES COc1c(F)cc(cc1F)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C19H19F2N3O6S3/c1-30-16-12(20)7-11(8-13(16)21)10-3-4-14-15(9-10)31-19(24-14)17(32(2,26)27)18(25)23-5-6-33(22,28)29/h3-4,7-9,17H,5-6H2,1-2H3,(H,23,25)(H2,22,28,29)
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n/an/a 1.70n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151507
PNG
(US8987314, B318)
Show SMILES CC1(O)CN(C1)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C23H26N4O7S3/c1-23(30)12-27(13-23)22(29)15-5-3-14(4-6-15)16-7-8-17-18(11-16)35-21(26-17)19(36(2,31)32)20(28)25-9-10-37(24,33)34/h3-8,11,19,30H,9-10,12-13H2,1-2H3,(H,25,28)(H2,24,33,34)
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n/an/a 1.80n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151559
PNG
(US8987314, B370)
Show SMILES COCCOc1ccc(cc1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C21H25N3O7S3/c1-30-10-11-31-16-6-3-14(4-7-16)15-5-8-18-17(13-15)24-21(32-18)19(33(2,26)27)20(25)23-9-12-34(22,28)29/h3-8,13,19H,9-12H2,1-2H3,(H,23,25)(H2,22,28,29)
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n/an/a 1.80n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
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