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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Enolase 1 (ENO1)' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Enolase 1 (ENO1)


(Homo sapiens (Human))
BDBM204924
PNG
(SF2312)
Show SMILES O[C@H]1C[C@@H](C(=O)N1O)P(O)(O)=O
Show InChI InChI=1/C4H8NO6P/c6-3-1-2(12(9,10)11)4(7)5(3)8/h2-3,6,8H,1H2,(H2,9,10,11)/t2-,3-/s2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PDB
UniChem
AffyNet 
Article
PubMed
n/an/a 37.9n/an/an/an/an/an/a



University of Texas MD Anderson Cancer Center



Assay Description
Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...


Citation and Details
More data for this
Ligand-Target Pair
Enolase 1 (ENO1)


(Homo sapiens (Human))
BDBM204923
PNG
(phosphonoacetohydroxamate (PhAH))
Show SMILES ONC(=O)CP(O)(O)=O
Show InChI InChI=1S/C2H6NO5P/c4-2(3-5)1-9(6,7)8/h5H,1H2,(H,3,4)(H2,6,7,8)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

DrugBank
PDB
UniChem
AffyNet 
Article
PubMed
n/an/a 53.2n/an/an/an/an/an/a



University of Texas MD Anderson Cancer Center



Assay Description
Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...


Citation and Details
More data for this
Ligand-Target Pair
Enolase 1 (ENO1)


(Homo sapiens (Human))
BDBM50103566
PNG
(CHEMBL3335790)
Show SMILES NCCOCCOCCNC(=O)Cc1ccc(Nc2nc(NCC3CCCCC3)nc(NCc3ccc(F)cc3)n2)cc1
Show InChI InChI=1S/C31H43FN8O3/c32-26-10-6-25(7-11-26)22-36-30-38-29(35-21-24-4-2-1-3-5-24)39-31(40-30)37-27-12-8-23(9-13-27)20-28(41)34-15-17-43-19-18-42-16-14-33/h6-13,24H,1-5,14-22,33H2,(H,34,41)(H3,35,36,37,38,39,40)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 576n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of ENO1 (unknown origin)


Bioorg Med Chem Lett 24: 4915-25 (2014)

More data for this
Ligand-Target Pair