BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)' AND taxid = 401614   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM8726
PNG
(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Show SMILES Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PDB
Article
PubMed
0.0510 -58.7n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36543
PNG
(5-propyl-2-phenoxyphenol | PT02)
Show SMILES CCCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C15H16O2/c1-2-6-12-9-10-15(14(16)11-12)17-13-7-4-3-5-8-13/h3-5,7-11,16H,2,6H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
0.440 -53.4n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM16296
PNG
(5-Pentyl-2-phenoxy-phenol | 5-pentyl-2-phenoxylphe...)
Show SMILES CCCCCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C17H20O2/c1-2-3-5-8-14-11-12-17(16(18)13-14)19-15-9-6-4-7-10-15/h4,6-7,9-13,18H,2-3,5,8H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
1.30 -50.7n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36539
PNG
(5-chloro-2-phenoxylphenol | PT52)
Show SMILES Oc1cc(Cl)ccc1Oc1ccccc1
Show InChI InChI=1S/C12H9ClO2/c13-9-6-7-12(11(14)8-9)15-10-4-2-1-3-5-10/h1-8,14H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1.90 -49.8n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36542
PNG
(5-methyl-2-phenoxylphenol | PT53)
Show SMILES Cc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C13H12O2/c1-10-7-8-13(12(14)9-10)15-11-5-3-2-4-6-11/h2-9,14H,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1.90 -49.8n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM16294
PNG
(2PP | 5-Ethyl-2-phenoxy-phenol | 5-butyl-2-phenoxy...)
Show SMILES CCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C14H14O2/c1-2-11-8-9-14(13(15)10-11)16-12-6-4-3-5-7-12/h3-10,15H,2H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
2.10 -49.5n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM16297
PNG
(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Show SMILES CCCCCCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C18H22O2/c1-2-3-4-6-9-15-12-13-18(17(19)14-15)20-16-10-7-5-8-11-16/h5,7-8,10-14,19H,2-4,6,9H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
2.70 -48.9n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36540
PNG
(5-bromo-2-phenoxylphenol | PT103)
Show SMILES Oc1cc(Br)ccc1Oc1ccccc1
Show InChI InChI=1S/C12H9BrO2/c13-9-6-7-12(11(14)8-9)15-10-4-2-1-3-5-10/h1-8,14H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
7.10 -46.5n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM16298
PNG
(5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphen...)
Show SMILES CCCCCCCCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C20H26O2/c1-2-3-4-5-6-8-11-17-14-15-20(19(21)16-17)22-18-12-9-7-10-13-18/h7,9-10,12-16,21H,2-6,8,11H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
23.6 -43.5n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36540
PNG
(5-bromo-2-phenoxylphenol | PT103)
Show SMILES Oc1cc(Br)ccc1Oc1ccccc1
Show InChI InChI=1S/C12H9BrO2/c13-9-6-7-12(11(14)8-9)15-10-4-2-1-3-5-10/h1-8,14H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
149 -39.0n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM16298
PNG
(5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphen...)
Show SMILES CCCCCCCCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C20H26O2/c1-2-3-4-5-6-8-11-17-14-15-20(19(21)16-17)22-18-12-9-7-10-13-18/h7,9-10,12-16,21H,2-6,8,11H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
192 -38.3n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36542
PNG
(5-methyl-2-phenoxylphenol | PT53)
Show SMILES Cc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C13H12O2/c1-10-7-8-13(12(14)9-10)15-11-5-3-2-4-6-11/h2-9,14H,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
247 -37.7n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36538
PNG
(5-fluoro-2-phenoxylphenol | PT55)
Show SMILES Oc1cc(F)ccc1Oc1ccccc1
Show InChI InChI=1S/C12H9FO2/c13-9-6-7-12(11(14)8-9)15-10-4-2-1-3-5-10/h1-8,14H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem
AffyNet 
Article
PubMed
289 -37.3n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36539
PNG
(5-chloro-2-phenoxylphenol | PT52)
Show SMILES Oc1cc(Cl)ccc1Oc1ccccc1
Show InChI InChI=1S/C12H9ClO2/c13-9-6-7-12(11(14)8-9)15-10-4-2-1-3-5-10/h1-8,14H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
308 -37.2n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM16294
PNG
(2PP | 5-Ethyl-2-phenoxy-phenol | 5-butyl-2-phenoxy...)
Show SMILES CCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C14H14O2/c1-2-11-8-9-14(13(15)10-11)16-12-6-4-3-5-7-12/h3-10,15H,2H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
311 -37.1n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM16297
PNG
(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Show SMILES CCCCCCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C18H22O2/c1-2-3-4-6-9-15-12-13-18(17(19)14-15)20-16-10-7-5-8-11-16/h5,7-8,10-14,19H,2-4,6,9H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
331 -37.0n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36543
PNG
(5-propyl-2-phenoxyphenol | PT02)
Show SMILES CCCc1ccc(Oc2ccccc2)c(O)c1
Show InChI InChI=1S/C15H16O2/c1-2-6-12-9-10-15(14(16)11-12)17-13-7-4-3-5-8-13/h3-5,7-11,16H,2,6H2,1H3
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
696 -35.1n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36541
PNG
(5-nitro-2-phenoxylphenol | PT104)
Show SMILES Oc1cc(ccc1Oc1ccccc1)N(=O)=O
Show InChI InChI=1S/C12H9NO4/c14-11-8-9(13(15)16)6-7-12(11)17-10-4-2-1-3-5-10/h1-8,14H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

AffyNet 
Article
PubMed
789 -34.8n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM36537
PNG
(2-phenoxylphenol | PT51)
Show SMILES Oc1ccccc1Oc1ccccc1
Show InChI InChI=1S/C12H10O2/c13-11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,13H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
2.26E+3 -32.2n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NAD+


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)


(Francisella tularensis)
BDBM8726
PNG
(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Show SMILES Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PDB
Article
PubMed
5.00E+3 -30.3n/an/an/an/an/a8.025



Stony Brook University



Assay Description
Inhibition constant binding to E-NADH


ACS Chem Biol 4: 221-31 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)