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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Equilibrative nucleoside transporter 2' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Equilibrative nucleoside transporter 2


(Rattus norvegicus)
BDBM50036307
PNG
(CHEMBL3353069)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)OCCN1CCN(CCOC(=O)c2cc(OC)c(OC)c(OC)c2)CC1
Show InChI InChI=1S/C28H38N2O10/c1-33-21-15-19(16-22(34-2)25(21)37-5)27(31)39-13-11-29-7-9-30(10-8-29)12-14-40-28(32)20-17-23(35-3)26(38-6)24(18-20)36-4/h15-18H,7-14H2,1-6H3
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Article
PubMed
n/an/a 977n/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Inhibition of rat ENT2 expressed in rat H9c2 cells by cell-based 3H[5-]uridine uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Equilibrative nucleoside transporter 2


(Rattus norvegicus)
BDBM50036308
PNG
(CHEMBL3353071)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)OCCCCN1CCN(CCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)CC1
Show InChI InChI=1S/C32H46N2O10/c1-37-25-19-23(20-26(38-2)29(25)41-5)31(35)43-17-9-7-11-33-13-15-34(16-14-33)12-8-10-18-44-32(36)24-21-27(39-3)30(42-6)28(22-24)40-4/h19-22H,7-18H2,1-6H3
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PubMed
n/an/a 1.08E+3n/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Inhibition of rat ENT2 expressed in rat H9c2 cells by cell-based 3H[5-]uridine uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Equilibrative nucleoside transporter 2


(Rattus norvegicus)
BDBM50036306
PNG
(CHEMBL3353070)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)OCCCN1CCN(CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)CC1
Show InChI InChI=1S/C30H42N2O10/c1-35-23-17-21(18-24(36-2)27(23)39-5)29(33)41-15-7-9-31-11-13-32(14-12-31)10-8-16-42-30(34)22-19-25(37-3)28(40-6)26(20-22)38-4/h17-20H,7-16H2,1-6H3
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PubMed
n/an/a 1.31E+3n/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Inhibition of rat ENT2 expressed in rat H9c2 cells by cell-based 3H[5-]uridine uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Equilibrative nucleoside transporter 2


(Rattus norvegicus)
BDBM50036309
PNG
(CHEMBL3353072)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)OCCCCN1CC(C)N(CCCCOC(=O)c2cc(OC)c(OC)c(OC)c2)CC1C
Show InChI InChI=1/C34H50N2O10/c1-23-21-36(14-10-12-16-46-34(38)26-19-29(41-5)32(44-8)30(20-26)42-6)24(2)22-35(23)13-9-11-15-45-33(37)25-17-27(39-3)31(43-7)28(18-25)40-4/h17-20,23-24H,9-16,21-22H2,1-8H3
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PubMed
n/an/a 1.49E+3n/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Inhibition of rat ENT2 expressed in rat H9c2 cells by cell-based 3H[5-]uridine uptake assay


Citation and Details
More data for this
Ligand-Target Pair
Equilibrative nucleoside transporter 2


(Rattus norvegicus)
BDBM50017691
PNG
(CHEMBL126075 | dilazep)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)OCCCN1CCCN(CCCOC(=O)c2cc(OC)c(OC)c(OC)c2)CC1
Show InChI InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3
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CHEMBL
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 8.80E+3n/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Inhibition of rat ENT2 expressed in rat H9c2 cells by cell-based 3H[5-]uridine uptake assay


Citation and Details
More data for this
Ligand-Target Pair