BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Excitatory Amino Acid EAAT2' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86712
PNG
(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)
Show SMILES N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O
Show InChI InChI=1S/C16H13BrF2N2O4/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24/h1-6,13H,7,20H2,(H,21,22)(H,23,24)/t13-/m0/s1
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
85n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86713
PNG
(WAY 213394 | WAY-213394)
Show SMILES Cc1ccccc1-c1ccc(NC(=O)C[C@H](N)C(O)=O)cc1
Show InChI InChI=1S/C17H18N2O3/c1-11-4-2-3-5-14(11)12-6-8-13(9-7-12)19-16(20)10-15(18)17(21)22/h2-9,15H,10,18H2,1H3,(H,19,20)(H,21,22)/t15-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
145n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86714
PNG
(WAY 212922 | WAY-212922)
Show SMILES N[C@@H](CC(=O)Nc1ccc-2c(Cc3cc(ccc-23)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C18H15F3N2O3/c19-18(20,21)11-1-3-13-9(6-11)5-10-7-12(2-4-14(10)13)23-16(24)8-15(22)17(25)26/h1-4,6-7,15H,5,8,22H2,(H,23,24)(H,25,26)/t15-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
157n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86711
PNG
(3-[3-Methyl-4-(4-chlorophenyl)benzoylamino]alanine...)
Show SMILES Cc1cc(ccc1-c1ccc(Cl)cc1)C(=O)NC[C@H](N)C(O)=O
Show InChI InChI=1S/C17H17ClN2O3/c1-10-8-12(16(21)20-9-15(19)17(22)23)4-7-14(10)11-2-5-13(18)6-3-11/h2-8,15H,9,19H2,1H3,(H,20,21)(H,22,23)/t15-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
190n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86316
PNG
(WAY-855)
Show SMILES N[C@]1([C@H]2C3C[C@@H]1C[C@@H]23)C(O)=O
Show InChI InChI=1S/C8H11NO2/c9-8(7(10)11)3-1-4-5(2-3)6(4)8/h3-6H,1-2,9H2,(H,10,11)/t3-,4+,5?,6+,8+/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.20E+3n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86316
PNG
(WAY-855)
Show SMILES N[C@]1([C@H]2C3C[C@@H]1C[C@@H]23)C(O)=O
Show InChI InChI=1S/C8H11NO2/c9-8(7(10)11)3-1-4-5(2-3)6(4)8/h3-6H,1-2,9H2,(H,10,11)/t3-,4+,5?,6+,8+/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.57E+3n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86317
PNG
(WAY-865)
Show SMILES N[C@]1([C@H]2C3C[C@H]1C[C@@H]23)C(O)=O
Show InChI InChI=1S/C8H11NO2/c9-8(7(10)11)3-1-4-5(2-3)6(4)8/h3-6H,1-2,9H2,(H,10,11)/t3-,4-,5?,6-,8-/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.57E+3n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Excitatory Amino Acid EAAT2


(HUMAN)
BDBM86315
PNG
(WAY-879)
Show SMILES N[C@@]1([C@H]2C3C[C@@H]1C[C@@H]23)C(O)=O
Show InChI InChI=1S/C8H11NO2/c9-8(7(10)11)3-1-4-5(2-3)6(4)8/h3-6H,1-2,9H2,(H,10,11)/t3-,4+,5?,6+,8-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair