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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Excitatory amino acid transporter 1' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Excitatory amino acid transporter 1


(Rattus norvegicus)
BDBM50292997
PNG
(2-Amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5...)
Show SMILES COc1ccc(cc1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1cccc2ccccc12
Show InChI InChI=1S/C27H22N2O3/c1-31-19-11-9-17(10-12-19)25-22(15-28)27(29)32-24-14-18(13-23(30)26(24)25)21-8-4-6-16-5-2-3-7-20(16)21/h2-12,18,22,25,29H,13-14H2,1H3
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PC cid
PC sid
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Similars

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Article
PubMed
n/an/a 970n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Activity at rat EAAT1 expressed in TSA201 cells assessed as inhibition of Glu-induced fluorescent response by FLIPR membrane potential blue assay


Citation and Details
More data for this
Ligand-Target Pair