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Compile Data Set for Download or QSAR

Found 11 hits Enz. Inhib. hit(s) with Target = 'Ezrin' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ezrin


(Homo sapiens)
BDBM50445461
PNG
(CHEMBL3104731)
Show SMILES Cc1cc(CC=Nc2cc(O)c3cccnc3c2O)cc(C)c1O
Show InChI InChI=1S/C19H18N2O3/c1-11-8-13(9-12(2)18(11)23)5-7-20-15-10-16(22)14-4-3-6-21-17(14)19(15)24/h3-4,6-10,22-24H,5H2,1-2H3
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n/an/an/a 5.00E+3n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445462
PNG
(CHEMBL3104730)
Show SMILES Oc1cc(N=CCc2cc(F)c(O)c(F)c2)c(O)c2ncccc12
Show InChI InChI=1S/C17H12F2N2O3/c18-11-6-9(7-12(19)16(11)23)3-5-20-13-8-14(22)10-2-1-4-21-15(10)17(13)24/h1-2,4-8,22-24H,3H2
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n/an/an/a 4.99E+4n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445463
PNG
(CHEMBL3104729)
Show SMILES Oc1cc(N=CCc2cc(Cl)c(O)c(Cl)c2)c(O)c2ncccc12
Show InChI InChI=1S/C17H12Cl2N2O3/c18-11-6-9(7-12(19)16(11)23)3-5-20-13-8-14(22)10-2-1-4-21-15(10)17(13)24/h1-2,4-8,22-24H,3H2
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n/an/an/a 8.00E+3n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445464
PNG
(CHEMBL3104728)
Show SMILES Oc1cc(N=CCc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)c(O)c2ncccc12
Show InChI InChI=1S/C31H26N2O4/c34-27-19-26(31(35)30-25(27)12-7-16-33-30)32-17-15-22-13-14-28(36-20-23-8-3-1-4-9-23)29(18-22)37-21-24-10-5-2-6-11-24/h1-14,16-19,34-35H,15,20-21H2
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n/an/an/a 2.53E+4n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445465
PNG
(CHEMBL3104725)
Show SMILES Oc1ccc(CC=Nc2cc(O)c3cccnc3c2O)cc1O
Show InChI InChI=1S/C17H14N2O4/c20-13-4-3-10(8-15(13)22)5-7-18-12-9-14(21)11-2-1-6-19-16(11)17(12)23/h1-4,6-9,20-23H,5H2
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n/an/an/a 7.90E+3n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50106508
PNG
(7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...)
Show SMILES Oc1cc(N=CCc2cc(Br)c(O)c(Br)c2)c(O)c2ncccc12
Show InChI InChI=1S/C17H12Br2N2O3/c18-11-6-9(7-12(19)16(11)23)3-5-20-13-8-14(22)10-2-1-4-21-15(10)17(13)24/h1-2,4-8,22-24H,3H2
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n/an/an/a 1.06E+4n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445467
PNG
(CHEMBL3104723)
Show SMILES COc1ccc(CC=Nc2cc(O)c3cccnc3c2O)cc1Br
Show InChI InChI=1S/C18H15BrN2O3/c1-24-16-5-4-11(9-13(16)19)6-8-20-14-10-15(22)12-3-2-7-21-17(12)18(14)23/h2-5,7-10,22-23H,6H2,1H3
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n/an/an/a 2.74E+4n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445468
PNG
(CHEMBL3104722)
Show SMILES COc1ccc(CC=Nc2cc(O)c3cccnc3c2O)cc1Cl
Show InChI InChI=1S/C18H15ClN2O3/c1-24-16-5-4-11(9-13(16)19)6-8-20-14-10-15(22)12-3-2-7-21-17(12)18(14)23/h2-5,7-10,22-23H,6H2,1H3
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n/an/an/a 7.00E+3n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445469
PNG
(CHEMBL3104721)
Show SMILES Oc1cc(N=CCc2cccc(Br)c2)c(O)c2ncccc12
Show InChI InChI=1S/C17H13BrN2O2/c18-12-4-1-3-11(9-12)6-8-19-14-10-15(21)13-5-2-7-20-16(13)17(14)22/h1-5,7-10,21-22H,6H2
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n/an/an/a 9.10E+3n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445470
PNG
(CHEMBL3104716)
Show SMILES Oc1cc(N=CCc2cc(Br)c(O)c(Br)c2)c(O)c2cnccc12
Show InChI InChI=1S/C17H12Br2N2O3/c18-12-5-9(6-13(19)17(12)24)1-4-21-14-7-15(22)10-2-3-20-8-11(10)16(14)23/h2-8,22-24H,1H2
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n/an/an/a 4.01E+4n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair
Ezrin


(Homo sapiens)
BDBM50445466
PNG
(CHEMBL3104724)
Show SMILES Oc1ccc(CC=Nc2cc(O)c3cccnc3c2O)cc1
Show InChI InChI=1S/C17H14N2O3/c20-12-5-3-11(4-6-12)7-9-18-14-10-15(21)13-2-1-8-19-16(13)17(14)22/h1-6,8-10,20-22H,7H2
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n/an/an/a 6.90E+3n/an/an/an/an/a



George Mason University

Curated by ChEMBL


Assay Description
Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometry


Citation and Details
More data for this
Ligand-Target Pair